Association between the expression of epithelial–mesenchymal transition (EMT)-related markers and oncologic outcomes of colorectal cancer
Mona Hany Emile,
Sameh Hany Emile,
Amr Awad El-Karef
et al.
Abstract:Background
Epithelial–mesenchymal transition (EMT) is a key step in the development of colorectal cancer (CRC) that confers metastatic capabilities to cancer cells. The present study aimed to assess the immunohistochemical (IHC) expression and impact of EMT markers, including E-cadherin, Vimentin, β-catenin, and SMAD4, on the oncologic outcomes of CRC.
Methods
This was a retrospective review of 118 CRC patients. Tissue slides were retrieved from the slide … Show more
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