Association Between Substance Use Diagnoses and Psychiatric Disorders in an Adolescent and Young Adult Clinic-Based Population

Welsh, Justine W.; Knight, John R.; Hou, Sherry Shu-Yeu; Malowney, Monica; Schram, Patricia; Sherritt, Lon; Boyd, J. Wesley

doi:10.1016/j.jadohealth.2016.12.018

Cited by 63 publications

(44 citation statements)

References 25 publications

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“…We performed polynomial regression to determine whether a significant change in type of substance used occurred with age. To establish an association between specific types of substance use and a psychiatric diagnosis, we dichotomized use problems, abuse and dependence into a single category to ensure greater power of analysis and performed multivariate analyses using logistic regression models to determine odds ratios (ORs) and 95% confidence intervals (95% CIs) after adjusting for covariates, including gender, age, and years of education. We defined the statistical significance threshold as an adjusted p ‐value of less than 0.05 after using a false discovery rate (FDR) correction for multiple comparisons.…”

Section: Methodsmentioning

confidence: 99%

Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults

Tejeda-Romero¹,

Kobashi-Margáin

Álvarez-Arellano

et al. 2018

American J Addict

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Background and Objectives Substance use disorders (SUDs) have high comorbidities with psychiatric disorders. Childhood and adolescence are particularly vulnerable developmental periods for the onset of SUDs. The objective of this study was to explore the differences, if any, between Mexican adolescents and young adults with respect to the prevalences of groups of psychiatric disorders, the types of substances used and the social factors involved. Methods This cross‐sectional study included 781 patients evaluated at the Youth Integration Center in Mexico City. The diagnostic criteria for SUDs and psychiatric disorders were defined according to the DSM‐IV and ICD‐10. Associations between SUDs and psychiatric disorders were evaluated via multivariate analysis using logistic regression models. Results The adolescents were more frequently substance abusers, whereas the adults had legal problems more often than the adolescents. We showed that adolescents using inhalants or cocaine were 1.62 more likely to have attention deficit hyperactivity disorder (ADHD). Moreover, adults using inhalants were 3.33 times more likely to meet the criteria for a psychotic disorder. Discussion and Conclusions We found that adolescents diagnosed with ADHD were more likely to have problems with use or abuse of or dependence on inhalants, and an elevated prevalence of parental SUDs was found in both the adolescent and adult groups. Scientific Significance Our findings indicate that earlier diagnosis and intervention are necessary in adolescents with ADHD and/or parental SUDs to prevent more advanced psychiatric diseases and adverse social consequences during adulthood. (Am J Addict 2018;XX:1–7)

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Section: Methodsmentioning

confidence: 99%

Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults

Tejeda-Romero¹,

Kobashi-Margáin

Álvarez-Arellano

et al. 2018

American J Addict

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“…Another study showed that individuals who met criteria for an OUD were more than twice as likely to have any anxiety-related diagnosis and more than 3 times as likely to have generalized anxiety disorder compared with adolescents who used primarily nonopioid substances. 37 Adolescents who have experienced trauma (eg, physical abuse, sexual abuse, neglect, family violence) have an increased risk of SUDs. In a study of adolescents aged 11e24 years receiving treatment in a SUDs clinic, 6% of participants reported posttraumatic stress disorder with increased risk for all categories of SUD with the exception of benzodiazepines.…”

Section: Social and Economic Risk Factors To Adolescent Opioid Misusementioning

confidence: 99%

Personal and Socioeconomic Determinants in Medication-assisted Treatment of Opioid Use Disorder in Adolescents and Young Adults

Grubb

2019

Clinical Therapeutics

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Opioid use disorder (OUD) is a pediatric and adolescent problem as most young adults (aged <25 years) in treatment programs report initiating use before 25 years of age, and there are lifelong impacts from early substance use necessitating early screening for opioid use and subsequent treatment. Medicationassisted treatment (MAT) is a highly effective intervention for OUD, and there is strong evidence for its use with adolescents; however, most adolescents with OUD are unable to access MAT or remain in MAT long term to achieve substantial recovery. Using case examples drawn from a pediatric and adolescent physician's experiences proving MAT to adolescents and young adults (ages 16e24 years), this article explores the personal and socioeconomic determinants in MAT of OUD in adolescents and young adults and provides suggestions for advocacy areas and resources to improve MAT with this population. (Clin Ther. 2019;41:1669e1680)

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“…Evidence suggests that internalizing symptoms may be related to the use of alcohol and illegal drugs (3,6,8,10,11). Depressive symptoms seem to be positively associated with certain beliefs that promote substance use.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Substance Use and Depressive Symptoms among Colombian Adolescents

Romero-Acosta¹,

Gómez-de-Regil²,

Lowe³

et al. 2018

West Indian Med J

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Objective: To explore the relationship between substance use and depressive symptomatology among adolescents in Colombia. Methods: Adolescents aged 13-19 years from a rural city in Colombia completed the Spanish version of the Alcohol,. Results: Regression analyses indicated that gender, having used cannabis, having used sedatives, and having a family member who used illegal drugs were predictive of higher symptom levels of depression according to KADS-6. Conclusion: The results of this study suggested that substance use was associated with depressive symptoms in this sample of Colombian adolescents. RESUMENObjetivo: Explorar la relación entre el uso de sustancias y la sintomatología depresiva entre adolescentes en Colombia. Métodos: Los adolescentes de 13 a 19 años de una ciudad rural en Colombia completaron la versión en español de la Prueba de Detección de Alcohol, Tabaco y Sustancias (ASSIST, en inglés) y la Escala de Depresión pasa Adolescentes de Kutcher-6 (KADS-6, en inglés). Resultados: Los análisis de regresión indicaron que tanto el género, como el haber consumido cannabis, usado sedantes, y tener un miembro de la familia que usó drogas ilegales, fueron predictores de niveles más altos de síntomas depresivos de acuerdo con la escala KADS-6. Conclusión: Los resultados de este estudio sugirieron que el uso de sustancias estaba asociado con síntomas depresivos en esta muestra de adolescentes colombianos.

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Association Between Substance Use Diagnoses and Psychiatric Disorders in an Adolescent and Young Adult Clinic-Based Population

Cited by 63 publications

References 25 publications

Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults

Differences in substance use, psychiatric disorders and social factors between Mexican adolescents and young adults

Personal and Socioeconomic Determinants in Medication-assisted Treatment of Opioid Use Disorder in Adolescents and Young Adults

The Relationship between Substance Use and Depressive Symptoms among Colombian Adolescents

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