Association between stress hyperglycemia on admission and unfavorable neurological outcome in OHCA patients receiving ECPR

Taira, Takuya; Inoue, Akihiko; Nishimura, Takeshi; Takahashi, Ryo; Isobe, Maho; Maemura, Saki; Suga, Michihiro; Ijuin, Shinichi; Masano, Tomoya; Matsuyama, Shogo; Ishihara, Satoshi; Kuroda, Yasuhiro; Nakayama, Shinichi

doi:10.1007/s00392-022-02057-4

Cited by 5 publications

(2 citation statements)

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“…We, therefore, feel that neglecting hypoglycemia in the present research significantly limits the conclusions that can be drawn from the presented dataset [ 1 ]. Clinicians are ill-advised using the suggested cutoff of blood glucose < 200 mg/dL as surrogate for poor prognosis in ECPR.…”

Section: Sirsmentioning

confidence: 99%

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Reply to: association between stress hyperglycemia on admission and unfavorable neurological outcome in OHCA patients receiving ECPR (https://doi.org/10.1007/s00392-022-02057-4)

2022

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With interest we read the article by Takuya Taira and coauthors on blood glucose levels and outcome in patients undergoing extracorporeal resuscitation (ECPR) [1]. The authors have to be complimented for their efforts in ECPR research. In their retrospective analysis of more than one hundred patients, the authors show a correlation between admission blood glucose levels and neurological outcome. The authors conclude that blood glucose of 200-300 mg/ dL (stress hyperglycemia) at admission is associated with favorable neurological outcome after cardiac arrest compared to blood glucose under 200 mg/dL. But association does not prove causality. A plausible

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Section: Sirsmentioning

confidence: 99%

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confidence: 99%