Association Between Sleep Duration and Sleep Disorder Data from the National Health and Nutrition Examination Survey and Stroke Among Adults in the United States

Abstract

Background We aimed to explore the association between sleep duration and sleep disorder variables obtained from the National Health and Nutrition Examination Survey (NHANES) and stroke. Material/Methods This cross-sectional study enrolled 10 442 participants from the United States. The outcome variable was stroke diagnosed by a doctor. Sleep disorder variables were assessed via self-report questionnaires and included sleep duration, the time required to fall asleep, frequency of sleep deprivation, frequency of early morning wakefulness, and frequency of middle of the night wakefulness. The odds ratio (OR) and 95% confidence intervals (CIs) were calculated by multivariate logistic regression models. Results Compared with participants with 6 to 7 h of sleep duration, participants with less than 6 h of sleep duration had an increased risk of stroke of 0.97 times (OR=1.97, 95% CI: 1.19–3.29). Participants with a sleep disorder had 0.71 times (OR=1.71, 95% CI: 1.04–2.82) the risk of stroke than those without a sleep disorder. Stroke was significantly associated with sleep deprivation 16 to 30 times a month (OR=1.99, 95% CI: 1.14–3.46), early morning wakefulness 16 to 30 times a month (OR=1.97, 95% CI: 1.20–3.25), and middle of the night wakefulness 16 to 30 times a month (OR=1.81, 95% CI: 1.05–3.09), compared with no sleep deprivation, early-morning wakefulness, or middle of the night wakefulness. Conclusions Short sleep duration and sleep disorder were associated with an increased risk of stroke, suggesting healthy sleep behaviors may reduce the risk of stroke. However, further studies are needed to confirm the causality and underlying mechanism.

The relationship between sleep quality, snoring symptoms, night shift and risk of stroke in Chinese over 40 years old

“…Stroke patients are prone to sleep disorders and may relapse several years after stroke (Jönsson et al, 2006 ). One research found that participants who slept for <6 h had a 0.97 times increased risk of stroke compared to those who slept for 6–7 h and participants with sleep disorders had 0.71 times the risk of stroke compared with those without sleep disorders (Wang and Ren, 2022 ). Our study found that people with a history of stroke and who were assessed to be at high risk of stroke had lower sleep quality.…”

Use of machine learning to identify risk factors for insomnia

“…Sleep is critical to a person's physical and mental health [1][2][3][4][5][6]. However, the prevalence of diagnosed sleep disorders among American patients has significantly increased over the past decade [1,5,[7][8][9][10].…”

“…Sleep is critical to a person's physical and mental health [1][2][3][4][5][6]. However, the prevalence of diagnosed sleep disorders among American patients has significantly increased over the past decade [1,5,[7][8][9][10]. Sleep disorders are a broad categorization of disorders that encompass conditions that lead to difficulty falling asleep, poor sleep quality, early waking, circadian rhythm disorders, parasomnias, sleep-related movement disorders, and sleep-related breathing disorders [11][12][13].…”

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