Association between short-term exposure to ambient air pollution and biomarkers of coagulation: A systematic review and meta-analysis

Wang, Kai; Wang, Wanzhou; Lei, Lei; Yang, Lan; Liu, Qisijing; Ren, Lihua; Wu, Shaowei

doi:10.1016/j.envres.2022.114210

Cited by 6 publications

(2 citation statements)

References 89 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the expression of inflammatory cytokines was demonstrated using the univariate analysis, after controlling for confounding variables (such as waist-to-hip ratio, education level, knowledge of indoor air pollution, use of air purifiers, smoking by family members in the house, exposure to incense burning, total duration of exercise, and PM 2.5 and NO 2 levels), only IL-1 β , IL-17A, and PAI-1 showed significant differences; there were no differences in EBC. The PAI-1 in our analysis was significant, which was consistent with the findings of Wang et al, who reported that short-term exposure to air pollutants, including PM 2.5 and NO 2 , is positively associated with PAI-1 (Wang et al 2022 ). Green et al ( 2016 ) reported that PAI-1 levels were related to long-term exposure to PM 2.5 in middle-aged women.…”

Section: Discussionsupporting

confidence: 92%

Exposure to incense burning, biomarkers, and the physical health of temple workers in Taiwan

Guo,

Ratner,

Tseng

et al. 2023

Environ Sci Pollut Res

View full text Add to dashboard Cite

Incense burning releases heavy particulate matter (PM) and nitrogen dioxide (NO2), known to have adverse effects on human health. Long-term exposure to PM and NO2 increases inflammatory cytokine levels and can induce respiratory diseases. This study examined the association between incense burning exposure and the health status, especially inflammatory biomarkers, of temple workers and volunteers in Taiwan. The longitudinal observational study compared adult temple workers and volunteers, with long-term incense burning exposure, to residents from outpatient clinics in the Chiayi area. Forced expiratory volume in 1 s (FEV1) and serum and exhaled breath condensate (EBC) cytokines were assessed. Nonparametric Mann-Whitney U tests were used to compare cytokine levels of the exposure and control groups during the cold and hot weather seasons. FEV1 was significantly more diminished in the exposed group than in the control group during the cold season. Exposure status was associated with greater hot-cold seasonal differences in serum interleukins (IL)-1β (regression coefficient (B) = 6.6, 95% confidence interval (CI) = 5.0 to 8.3, p < .001), IL17-A (B = 2.4, 95% CI = 0.3 to 4.5, p = .03), and plasminogen activator inhibitor [PAI]-1 (B = 5.4, 95% CI = 1.5 to 9.3, p = .009). After adjusting for confounders, the groups’ serum levels of IL-1β, IL-17A, and PAI-1 significantly differed. EBC cytokines did not show significant differences. Elevated levels of IL-1β, IL17-A, and PAI-1 have been associated with various autoinflammatory syndromes and diseases. Given the cultural significance of incense burning, culturally sensitive interventions, including education, policy development, and program implementation, are crucial to protect individuals’ health, especially temple workers, from the adverse effects of exposure, addressing the manufacture, importation, and sale of incense.

show abstract

Section: Discussionsupporting

confidence: 92%

Exposure to incense burning, biomarkers, and the physical health of temple workers in Taiwan

Guo,

Ratner,

Tseng

et al. 2023

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…Associations between both gaseous and particulate matter pollutants and acute thromboembolic cardiovascular events have been described before [ 7 , 8 , 9 , 10 , 11 , 12 ]. Several mechanisms by which air pollution induces an activated coagulation state are suggested, including induction of endothelial dysfunction and inflammatory responses, as well as generation of reactive species and alteration of coagulation factors [ 43 , 44 , 45 , 46 , 47 , 48 ].…”

Section: Discussionmentioning

confidence: 99%

Exploring the Effects of Local Air Pollution on Popliteal Artery Aneurysms

Leinweber,

Meisenbacher,

Schmandra

et al. 2024

JCM

View full text Add to dashboard Cite

Objectives: A growing body of evidence highlights the effects of air pollution on chronic and acute cardiovascular diseases, such as associations between PM10 and several cardiovascular events. However, evidence of the impact of fine air pollutants on the development and progression of peripheral arterial aneurysms is not available. Methods: Data were obtained from the multicenter PAA outcome registry POPART and the German Environment Agency. Means of the mean daily concentration of PM10, PM2.5, NO2, and O3 concentrations were calculated for 2, 10, and 3650 days prior to surgery for each patient. Additionally, weighted ten-year averages were analyzed. Correlation was assessed by calculating Pearson correlation coefficients, and regression analyses were conducted as multiple linear or multiple logistic regression, depending on the dependent variable. Results: For 1193 patients from the POPART registry, paired air pollution data were available. Most patients were male (95.6%) and received open surgical repair (89.9%). On a regional level, the arithmetic means of the daily means of PM10 between 2000 and 2022 were neither associated with average diameters nor runoff vessels. Negative correlations for mean PAA diameter and mean NO2, as well as a positive correlation with mean O3, were found; however, they were not statistically significant. On patient level, no evidence for an association of mean PM10 exposure over ten years prior to inclusion in the registry and PAA diameter or the number of runoff vessels was found. Weighted PM10, NO2, and O3 exposure over ten years also did not result in significant associations with aneurysm diameter or runoff vessels. Short-term air pollutant concentrations were not associated with symptomatic PAAs or with perioperative complications. Conclusions: We found no indication that long-term air pollutant concentrations are associated with PAA size or severity, neither on a regional nor individual level. Additionally, short-term air pollution showed no association with clinical presentation or treatment outcomes.

show abstract

Long-term exposure to air pollution on cardio-respiratory, and lung cancer mortality: a systematic review and meta-analysis

Karimi,

Samadi

2024

J Environ Health Sci Engineer

View full text Add to dashboard Cite

Association between short-term exposure to ambient air pollution and biomarkers of coagulation: A systematic review and meta-analysis

Cited by 6 publications

References 89 publications

Exposure to incense burning, biomarkers, and the physical health of temple workers in Taiwan

Exposure to incense burning, biomarkers, and the physical health of temple workers in Taiwan

Exploring the Effects of Local Air Pollution on Popliteal Artery Aneurysms

Long-term exposure to air pollution on cardio-respiratory, and lung cancer mortality: a systematic review and meta-analysis

Contact Info

Product

Resources

About