Association Between MRI‐Assessed Patterns of Connectome Gradient and Gene‐Expression Profiles in Two Independent Patient Cohorts With Hepatitis B Virus‐Related Cirrhosis
Abstract:BackgroundPatients with hepatitis B virus‐related cirrhosis (HBV‐RC) exhibit progressive neurologic dysfunction from primary sensorimotor to high‐order cognition, as their disease advances. However, the exact neurobiologic mechanisms and the potential association with gene‐expression profiles are not fully understood.PurposeTo explore the hierarchical disorganization in the large‐scale functional connectomes in HBV‐RC patients and to investigate its potential underlying molecular basis.Study TypeProspective.Po… Show more
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