Association Between Rheumatoid Arthritis and Clonal Hematopoiesis: A Mendelian Randomization Study
Jie Zhang,
Chun Zhou,
Shaoxing Guan
Abstract:Immunity activation and inflammation are the main characteristics of rheumatoid arthritis and clonal hematopoiesis. However, it remains unclear whether rheumatoid arthritis increase the risk of clonal hematopoiesis. Here, a Mendelian randomization (MR) analysis was conduct to explore the causal effects of rheumatoid arthritis on clonal hematopoiesis. Summary statistics data of rheumatoid arthritis (13,838 cases and 33,742 controls) and clonal hematopoiesis (10,203 cases and 173,918 controls) derived from a gen… Show more
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