Association between Reproductive Span and Sarcopenia

Park, Eun Young; Han, Kyoung Hee; Chung, Tae-Ha; Kim, Nam Yun; Lee, Ji Min; Choi, Seong Jin; Kim, Jong Koo

doi:10.3390/ijerph18010154

Cited by 10 publications

(9 citation statements)

References 38 publications

(56 reference statements)

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“…Sampling weights were used to determine the annual prevalence of OC use. The sampling weights were estimated by the following three factors: the sample selection probability, the adjustment for non-response, and the post-stratification factor [ 14 ]. Sampling weights calculated by the Korea Centers for Disease Control and Prevention were used in this study.…”

Section: Methodsmentioning

confidence: 99%

Trends and Factors Associated with Oral Contraceptive Use among Korean Women

Park

Kim

2021

Healthcare

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Although oral contraceptives (OC) are widely used, few national-level epidemiologic studies have evaluated the prevalence of OC use and factors related to their use in Korea. We performed a population-based cross-sectional study on OC use by premenopausal women aged 20–59 years residing in Korea. We used secondary data from the 2010–2019 National Health and Nutrition Examination Survey to examine trends in the annual prevalence of OC use between 2010 and 2019, and factors influencing OC use. Based on data from 14,386 premenopausal women, the average annual prevalence of OC use was 8.2–10.7% between 2010 and 2014; it increased to 12.6–14.4% during 2015–2019. The prevalence of OC use was significantly higher in women with higher (≥5) than lower gravidity (<5). In addition, among sociodemographic factors, education level, household income, cigarette smoking, and alcohol drinking were significantly associated with OC use in Korean women. As OC use is affected by sociodemographic factors, a contraceptive plan that considers sociodemographic factors is needed to establish an effective family planning policy.

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Section: Methodsmentioning

confidence: 99%

Trends and Factors Associated with Oral Contraceptive Use among Korean Women

Park

Kim

2021

Healthcare

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“…Participants (n = 37,702) with age <20 years were excluded. Other participants were excluded due to lack of sociodemographic status (n = 98), questionnaire (n = 7451), physical examination (10,683) and laboratory data (n = 1,903). Individuals with diabetes onset age <30 years (n = 311) was also excluded to minimize the confounding from type 1 diabetes mellitus.…”

Section: Study Populationmentioning

confidence: 99%

“…Sarcopenia was defined as ASM BMI <0.512 for females and <0.789 for males. The cut-off values were based on the Foundation for the National Institutes of Health (FNIH) sarcopenia project criteria (10). Participants with weigh over 450 pounds or height over 192.5 cm were not measured by DXA.…”

Section: Study Variables Outcomesmentioning

confidence: 99%

“…Sarcopenia, defined as a syndrome caused by the continuous loss of skeletal muscle mass, strength, and function, has become a serious concern, especially in the elderly (1). Aging, reduction of activity, neuromuscular dysfunction, and changes in aging-related hormones (insulin, growth hormone, sex hormone, glucocorticoid) are all involved in the development 10.3389/fnut.2023.1109824 of sarcopenia (2). Although sarcopenia is considered an inevitable manifestation of aging, the severity is variable depending on various factors affecting muscle metabolism (3).…”

Section: Introductionmentioning

confidence: 99%

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Prediabetes is associated with loss of appendicular skeletal muscle mass and sarcopenia

Mao

Zhou

2023

Front. Nutr.

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BackgroundDecreasing mass and metabolism in skeletal muscle are associated with increasing insulin resistance (IR) and type 2 diabetes mellitus (T2DM). The causal relation between sarcopenia and abnormal glucose metabolism may be bidirectional. This investigation is aimed to explore the detailed correlation between pre-diabetes and sarcopenia in United States (US) adults.MethodsA total of 22,482 adults aged ≥20 years in the National Health and Nutrition Examination Survey (NHANES) were included. Generalized linear models were conducted to examine associations between diabetes status, serum glucose, glycohemoglobin (HbA1c), and sarcopenia. Generalized additive models and smooth fitting curves were used to examine the non-linear relationship between HbA1c and ASMBMI. Sarcopenia was defined as ASMBMI (appendicular skeletal muscle mass/body mass index) < 0.789 for males, and <0.512 for females based on the cut-off values of the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project.ResultsAfter fully adjusting for multiple covariates, sarcopenia was directly correlated with pre-diabetes [OR (95%CI) = 1.230 (1.057, 1.431), p = 0.008] and T2DM [OR (95%CI) = 2.106 (1.625, 2.729), p < 0.001]. In non-T2DM population, HbA1c was negatively correlated with ASMBMI [β (95%CI) = −0.009 (−0.013, −0.005), p < 0.001]. The correlations only persisted in males. Furthermore, in male non-T2DM population, the association of HbA1c and ASMBMI presents an inverted U-shape curve with an inflection point of HbA1c 5.2%.ConclusionPre-diabetes is associated with increased risk of sarcopenia. HbA1c is an independent risk factor for loss of appendicular skeletal muscle mass and sarcopenia when HbA1c greater than 5.2% in the male non-T2DM population.

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“…In addition, only one study has investigated the relationship between the reproductive period and sarcopenia, which found that the longer the reproductive period, the lesser the sarcopenia, based on the Foundation for the National Institutes of Health sarcopenia project criteria: appendicular skeletal muscle mass/body mass index (BMI) < 0.512. 8 Consensus groups now recommend screening for sarcopenia by first checking handgrip strength (HGS), which is a simple and reliable test that measures muscle quality, strength, and mass by assessing voluntary maximum hand strength. 9 However, to the best of our knowledge, no study has investigated the relationship between HGS and the reproductive period.…”

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confidence: 99%

The association between reproductive period and handgrip strength in postmenopausal women: a nationwide cross-sectional study

Lee,

Cho,

Park

et al. 2023

Menopause

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Objective Menarche and menopause are associated with muscle loss and strength in women. Handgrip strength (HGS) is a reliable measurement method of muscle strength. However, it is unclear whether the entire reproductive period, which encompasses both menarche and menopause, is associated with HGS in postmenopausal women. Methods A total of 2,354 postmenopausal women aged 45-75 years were included for statistical analysis. The reproductive period was divided into tertiles, and HGS was divided into four quartiles. HGS was measured to evaluate muscle strength. Binary logistic regression analysis was used to identify significant predictors with the first quartile HGS, derived from quartile data. Multiple logistic regression analysis was used to assess the relationship between the reproductive period (exposure) and low HGS (outcome). Results We found that the more extended the reproductive period, the lower the risk of low absolute HGS. This trend persisted even after controlling for other variables. Specifically, the odds ratio for low absolute HGS was 0.752 (95% confidence interval [CI], 0.563-1.000) for the second tertile reproductive period and 0.683 (95% CI, 0.513-0.900) for the third tertile reproductive period, with the first tertile reproductive period as the reference. The odds ratio for low relative HGS was 0.761 (95% CI, 0.551-1.052) for the second tertile reproductive period and 0.732 (95% CI, 0.533-0.972) for the third tertile reproductive period, using first tertile reproductive period as the reference, after covariate adjustment. Conclusions A longer reproductive period is associated with a decreased risk of low HGS in postmenopausal women.

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Association between Reproductive Span and Sarcopenia

Cited by 10 publications

References 38 publications

Trends and Factors Associated with Oral Contraceptive Use among Korean Women

Trends and Factors Associated with Oral Contraceptive Use among Korean Women

Prediabetes is associated with loss of appendicular skeletal muscle mass and sarcopenia

The association between reproductive period and handgrip strength in postmenopausal women: a nationwide cross-sectional study

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