Association between relative bone mass and vitamin D receptor gene polymorphism

The divergence of genetic complexes in anthropologically related populations with different types of management of natural resources

“…4, pp. 99 110 ñîêîé äîëåé ãåòåðîçèãîò CT*Fok1, äëÿ êîòîðûõ ïîêàçàí áîëüøèé âêëàä êîñòíîé òêàíè â îáùóþ ìàññó òåëà ïî ñðàâíåíèþ ñ ãîìîçèãîòàìè TT [Kozlov et al, 2017].…”

“…Ðÿä èññëåäîâàíèé óêàçûâàåò òàêaeå íà âëèÿíèå íà ìåòàáîëèçì êîñòíîé òêàíè ïîëèìîðôèçìà ãåíà BsmI. Â ñåâåðíûõ åâðîïåîèäíûõ ãðóïïàõ íîñèòåëüñòâî ãîìîçèãîòíîãî âàðèàíòà T/T*BsmI àññîöèèðîâàíî ñî ñíèaeåíèåì ýôôåêòèâíîñòè àáñîðáöèè êàëüöèÿ ïî ñðàâíåíèþ ñ ãîìîçèãîòàìè *C/C è îñîáåííî ãåòåðîçèãîòàìè *C/T [Kozlov et al, 2017].…”

Anthropological and ecological specificity of polymorphism in genes related to bone tissue metabolism (as exemplified by the Shors people)

“…Âûáîðêà øîðöåâ õàðàêòåðèçóåòñÿ î÷åíü âûñîêèì íîñèòåëüñòâîì àëëåëÿ C*Fok1 (66,2%) è ãåíîòèïîâ CC*Fok1 è CT*Fok1 (òàáë. 1, 2), çíà÷èìî ïðåâîñõîäÿ îáñëåäîâàííûõ ðàíåå êîìè è óðîaeåíöåâ Åâðîïåéñêîé ÷àñòè ÐÔ [Kozlov et al, 2014;Kozlov, Vershubskaya, Negasheva, 2017].…”

“…Èìåþòñÿ òàêaeå ñâåäåíèÿ î âëèÿíèè íà ìåòàáîëèçì êîñòíîé òêàíè ïîëèìîðôèçìà ãåíà VDR BsmI (rs1544410).  ñåâåðíûõ åâðîïåîèäíûõ ãðóïïàõ (ðóññêèå, êîìè) íîñèòåëüñòâî ãîìîçèãîòíîãî âàðèàíòà AA*BsmI àññîöèèðîâàíî ñî ñíèaeåíèåì ýôôåêòèâíîñòè àáñîðáöèè êàëüöèÿ ïî ñðàâíåíèþ ñ ãîìîçèãîòàìè *GG è îñîáåííî ãåòåðîçèãîòàìè *GA [Kozlov et al, 2014;Kozlov, Vershubskaya, Negasheva, 2017]. Ýòè íàáëþäåíèÿ ñîãëàñóþòñÿ ñ äàííûìè, ïîëó÷åííûìè â äðóãèõ âûáîðêàõ Ñåâåðíîé Åâðîïû [Dawson-Hughes et al 1995;Ferrara et al, 2002;Grundberg et al, 2004].…”

Gene pool reflects traditional diet peculiarities of ethnic groups practicing taiga-forest type of economy

“…Èìåþòñÿ òàêaeå ñâåäåíèÿ î âëèÿíèè íà ìåòàáîëèçì êîñòíîé òêàíè ïîëèìîðôèçìà ãåíà VDR BsmI (rs1544410). Â ñåâåðíûõ åâðîïåîèäíûõ ãðóïïàõ íîñèòåëüñòâî ãîìîçèãîòíîãî âàðèàíòà TT*BsmI àññîöèèðîâàíî ñî ñíèaeåíèåì ýôôåêòèâíîñòè àáñîðáöèè êàëüöèÿ ïî ñðàâíåíèþ ñ ãîìîçèãîòàìè *CC è îñîáåííî ãåòåðîçèãîòàìè *CT [Grundberg et al, 2004;Kozlov et al, 2014;Kozlov et al, 2017].…”