2020
DOI: 10.1136/postgradmedj-2019-137357
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Association between pulse pressure and ischaemic stroke in elderly patients with hypertension

Abstract: BackgroundThe association between pulse pressure (PP) and the risk of first ischaemic stroke (IS) is inconsistent. Therefore, we evaluated the association between PP and the risk of first IS among elderly hypertensive population in China.MethodsThis was a retrospective cohort study. Patients with hypertension and aged ≥60 years were recruited. Multivariate Cox regression was performed to evaluate the association between PP and the risk of IS. We further stratified the regression models into subgroups and test … Show more

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Cited by 5 publications
(3 citation statements)
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“…Higher pulse pressure was associated with first ischemic stroke (aHR per SD, 1.17 [95% CI, 1.05–1.40]) in a study of hypertensive adults ≥60 years of age who annually attended physical examination in the community health care center in Guangdong, China. 47…”
Section: Stroke Risk Factorsmentioning
confidence: 99%
“…Higher pulse pressure was associated with first ischemic stroke (aHR per SD, 1.17 [95% CI, 1.05–1.40]) in a study of hypertensive adults ≥60 years of age who annually attended physical examination in the community health care center in Guangdong, China. 47…”
Section: Stroke Risk Factorsmentioning
confidence: 99%
“…Higher pulse pressure was associated with first ischemic stroke (aHR per SD, 1.17 [95% CI, 1.05–1.40]) in a study of hypertensive adults ≥60 years of age who annually attended physical examination in the community health care center in Guangdong, China. 18…”
Section: Stroke (Cerebrovascular Diseases)mentioning
confidence: 99%
“…The effect of BP on stroke had a dose-response relationship, and there was no threshold ( 37 ). For each 1 mmHg increase in SBP or DBP, the risk of stroke increased by 1.05–1.40 times ( 38 ). HTN can damage the intima of blood vessels and activate the blood coagulation system, which in turn, can cause blood vessel stenosis and eventually lead to stroke ( 39 ).…”
Section: Discussionmentioning
confidence: 99%