Association between prenatal exposure to PM2.5 and the increased risk of specified infant mortality in South Korea

Jung, Eun Mi; Kim, Kyoung Nam; Park, Hyesook; Shin, Hwashin Hyun; Kim, Hae Soon; Cho, Su Jin; Kim, Soon Tae; Ha, Eun Hee

doi:10.1016/j.envint.2020.105997

Cited by 25 publications

(16 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some studies have found that exposure to higher levels of post-birth air pollution increases the risk of infant death but increased prenatal air pollution exposure does not [ 3 , 4 ]. In contrast, other studies have found that higher levels of prenatal air pollution exposure increases the risk of infant death, but post-birth air pollution exposure does not [ 5 , 6 ]. Furthermore, some studies have also suggested that both prenatal and post-birth air pollution exposure may increase the risk of infant mortality [ 7 , 8 ].…”

Section: Introductionmentioning

confidence: 96%

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Khadka

Canning

2021

IJERPH

View full text Add to dashboard Cite

We studied the relationship of prenatal and post-birth exposure to particulate matter < 2.5 μm in diameter (PM2.5) with infant mortality for all births between 2011 and 2013 in the conterminous United States. Prenatal exposure was defined separately for each trimester, post-birth exposure was defined in the 12 months following the prenatal period, and infant mortality was defined as death in the first year of life. For the analysis, we merged over 10 million cohort-linked live birth–infant death records with daily, county-level PM2.5 concentration data and then fit a Structural Equation Model controlling for several individual- and county-level confounders. We estimated direct paths from the two exposures to infant death as well as indirect paths from the prenatal exposure to the outcome through preterm birth and low birth weight. Prenatal PM2.5 exposure was positively associated with infant death across all trimesters, although the relationship was strongest in the third trimester. The direct pathway from the prenatal exposure to the outcome accounted for most of this association. Estimates for the post-birth PM2.5–infant death relationship were less precise. The results from our study add to a growing literature that provides evidence in favor of the potential harmful effects on human health of low levels of air pollution.

show abstract

Section: Introductionmentioning

confidence: 96%

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Khadka

Canning

2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…Moreover, previous studies often used disease classification codes when collecting data about congenital anomalies. 21 22 However, the present study included data on specific types of congenital anomalies for 1,624 infants by having clinicians cross review EMRs and radiologic findings, in addition to disease classification codes. This also enhanced the accuracy of the data.…”

Section: Discussionmentioning

confidence: 99%

Correlation between Exposure to Fine Particulate Matter (PM_2.5) during Pregnancy and Congenital Anomalies: Its Surgical Perspectives

et al. 2021

View full text Add to dashboard Cite

Background Fine particulate matter (PM 2.5 ) can easily penetrate blood vessels and tissues through the human respiratory tract and cause various health problems. Some studies reported that particular matter (PM) exposure during pregnancy is associated with low birth weight or congenital cardiovascular anomalies. This study aimed to investigate the correlation between the degree of exposure to PM ≤ 2.5 μm (PM 2.5 ) during pregnancy and congenital anomalies relevant to the field of pediatric surgery. Methods Mother-infant dyads with registered addresses in the Metropolitan City were selected during 3 years. The electronic medical records of mothers and neonates were retrospectively analyzed, with a focus on maternal age at delivery, date of delivery, gestation week, presence of diabetes mellitus (DM) or hypertension, parity, the residence of the mother and infant, infant sex, birth weight, Apgar score, and presence of congenital anomaly. The monthly PM 2.5 concentration from the first month of pregnancy to the delivery was computed based on the mothers' residences. Results PM 2.5 exposure concentration in the second trimester was higher in the congenital anomaly group than in the non-congenital anomaly group (24.82 ± 4.78 µg/m 3 , P = 0.023). PM 2.5 exposure concentration did not affect the incidence of nervous, cardiovascular, and gastrointestinal anomalies. While statistically insignificant, the groups with nervous, cardiovascular, gastrointestinal, musculoskeletal, and other congenital anomalies were exposed to higher PM 2.5 concentrations in the first trimester compared with their respective counterparts. The effect of PM 2.5 concentration on the incidence of congenital anomalies was significant even after adjusting for the mother's age, presence of DM, hypertension, and parity. The incidence of congenital anomalies increased by 26.0% (95% confidence interval of 4.3% and 49.2%) per 7.23 µg/m 3 elevation of PM 2.5 interquartile range in the second trimester. Conclusions The congenital anomaly group was exposed to a higher PM 2.5 concentration in the second trimester than the non-congenital anomaly group. The PM 2.5 exposure concentration level in the first trimester tended to be higher in groups with anomalies than those without anomalies. This suggests that continuous exposure to a high PM 2.5 concentration during pregnancy influences the incidence of neonatal anomalies in surgical respects.

show abstract

“…Our results showed that the RR was statistically signi cant only for PM 2.5 in infants (RR =0.90, 95%CI 0.82-0.99). And a study ndings suggested that parental exposure to PM 2.5 could increase infant mortality differently by the timing of exposure and gender, which suggested a relation to fetal development in South Korea [29] . Zwozdziak et al reported a decrease in lung function parameters with increasing exposure of indoor PM 1 in school children [30] .…”

Section: Discussionmentioning

confidence: 99%

Acute Effects of Ambient Air Pollution on Lower Respiratory Infections in Guangzhou Children of China

Hua-wen¹,

Yang

Wang

et al. 2021

Preprint

View full text Add to dashboard Cite

Daily concentrations of air pollution are associated with lower respiratory diseases. We investigated the short-term association of ambient air pollution with daily hospital admissions due to pneumonia among children aged 0−17 in Guangzhou city of China. Ambient air pollutants were all positively associated with children hospital admissions due to pneumonia of all ages. Significant associations were found for air pollutants except for inhalable particulate matter (PM) \(\le\)10 µm in aerodynamic diameter (PM10) in children of all ages. Increments of an interquartile range (IQR) (279.10µg/m3 and 28.42µg/m3, respectively) in the 7-day-average level of carbon monoxide (CO) and nitrogen dioxide (NO2) were associated with a 26.17% (95% confidence interval (CI) 1.40%-56.98%) and 25.09% (95%CI 0.54%-55.64%) increase in pneumonia hospitalizations for children aged 6−17, respectively. An IQR increase in CO concentrations was associated with a 15.15% (95%CI 4.34%-27.08%) increase in pneumonia hospitalizations for children aged 1−5. Daily cases of microbial detection for pneumonia were positively associated with daily NO2 concentration. The pneumonia hospitalizations due to Mycoplasma pneumonia, Flu A virus and Flu B virus, the predominant pathogenic microorganisms detected in children aged 0−5 are apparently associated with levels of PMs, CO, NO2 and O3.

show abstract

Association between prenatal exposure to PM2.5 and the increased risk of specified infant mortality in South Korea

Cited by 25 publications

References 53 publications

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Correlation between Exposure to Fine Particulate Matter (PM_2.5) during Pregnancy and Congenital Anomalies: Its Surgical Perspectives

Acute Effects of Ambient Air Pollution on Lower Respiratory Infections in Guangzhou Children of China

Contact Info

Product

Resources

About

Association between prenatal exposure to PM2.5 and the increased risk of specified infant mortality in South Korea

Cited by 25 publications

References 53 publications

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Understanding the Pathways from Prenatal and Post-Birth PM2.5 Exposure to Infant Death: An Observational Analysis Using US Vital Records (2011–2013)

Correlation between Exposure to Fine Particulate Matter (PM2.5) during Pregnancy and Congenital Anomalies: Its Surgical Perspectives

Acute Effects of Ambient Air Pollution on Lower Respiratory Infections in Guangzhou Children of China

Contact Info

Product

Resources

About

Correlation between Exposure to Fine Particulate Matter (PM_2.5) during Pregnancy and Congenital Anomalies: Its Surgical Perspectives