Association between Pre-Existing Coronary Artery Disease and 5-Year Mortality in Stroke Patients with High-Grade Carotid Artery Stenosis

Wu, Ching-I; Wu, Chia-Lun; Su, Feng-Chieh; Lin, Shun-Wen; Huang, Wen‐Yi

doi:10.1159/000512407

Cited by 1 publication

(2 citation statements)

References 23 publications

(31 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[16,17] preexisting CAD is associated with poor outcomes in stroke rehabilitation as well as an increased risk of short-term and long-term mortality. [11,18] Our findings are in accordance with those of previous studies in that patients with CAD showed poorer motor outcomes in the lower extremities and gait ability 6 months after the onset of stroke when compared to patients without CAD. Notably, these poorer outcomes in motor recovery were only observed in the lower extremities.…”

Section: Discussionsupporting

confidence: 92%

“…[ 6 , 7 ] In addition, previous studies have identified that preexisting HF is associated with increased mortality in stroke patients as well as unfavorable functional outcomes at discharge. [ 8 – 10 ] Similarly, coronary artery disease (CAD) is independently associated with increased mortality in patients with stroke, [ 11 ] and is the most common etiology of HF. [ 12 ] However, most studies have evaluated the functional status of patients using only modified Ranking Scale score, a seven-point scale ranging from 0 (no symptoms) to 6 (death), rather than directly evaluating motor function, and did not control for factors that can affect motor recovery after stroke other than age and stroke severity represented by National Institutes of Health Stroke Scale scores.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The effect of preexisting heart failure and coronary artery disease on motor function recovery in cerebral infarct patients: A retrospective observational study

Kwak,

Chang

2023

Medicine

View full text Add to dashboard Cite

Less is known about the impact of heart failure (HF) and coronary artery disease (CAD) on motor recovery after cerebral infarction although previous studies have reported that preexisting HF and CAD were associated with increased mortality in stroke patients as well as unfavorable functional outcomes. In this study, we aimed to accurately evaluate the impact of HF and CAD on motor recovery after cerebral infarction by including only patients with corona radiata using diffusion tensor tractography. A total of 110 patients were recruited, and diffusion tensor tractography was performed within 7 to 30 days of infarct onset. Motor function on the affected side was evaluated for each patient using the upper myocardial infarction (MI), lower MI, modified Brunnstrom classification, and the functional ambulation category at the onset of stroke and 6 months after the onset of stroke. The influence of preexisting HF and CAD on the recovery of motor function were analyzed, adjusting for critical factors for motor recovery after stroke, namely the corticospinal tract condition, lesion location, age, and upper and lower MIs at the onset of stroke. No significant difference was found in motor outcomes according to the presence of HF, while poorer outcomes in motor function of the lower extremities and gait ability were observed in patients with CAD compared to patients without CAD. Motor function of the lower extremities and gait ability in cerebral infarct patients with CAD is more impaired than those without CAD.

show abstract