Association Between Postoperative Acute Kidney Injury and Duration of Cardiopulmonary Bypass: A Meta-Analysis

Kumar, Avinash B.; Suneja, Manish; Bayman, Emine O.; Weide, Garry D.; Tarasi, Michele

doi:10.1053/j.jvca.2011.07.007

Cited by 104 publications

(78 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, a meta-analysis found that this period represents an independent risk factor for acute kidney injury. (18) In this sense, the present study found a statistically significant relationship (p = 0.01) between the type of surgery and cardiopulmonary bypass time.…”

Section: Discussionsupporting

confidence: 59%

“…(16) Despite the scientific and technological advances in the health field, the approach of acute kidney injury is complex and challenging due to lack of criteria for its classification of complexity and early identification. (17,18) Thus, implementing the KDIGO classification system enabled the recognition and stratification of acute kidney injury in the intensive care setting.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Lesão renal aguda no pós-operatório de cirurgia cardíaca

Nascimento

Aguiar²,

Silva

et al. 2015

Acta paul. enferm.

View full text Add to dashboard Cite

Objective: To identify the occurrence of acute kidney injury (AKI) in the postoperative period of cardiac surgery. Methods: A prospective cohort study including 51 patients exposed to coronary artery bypass surgery, valve replacement, or combined surgery (bypass surgery and valve replacement) without history of kidney disease and kidney transplant, and who were followed from the preoperative period until 72 hours after surgery. Acute renal failure was defined as baseline creatinine increase of 0.3 mg/dL in 48 hours or less, or its increase from 1.5 to 1.9-fold, or a reduction in urine flow <0.5mL/kg/h for 6 hours. The Kidney Disease: Improving Global Outcomes (KDIGO) classification was used. Results: The KDIGO classification showed that 92.2% of patients had renal impairment. The urinary flow criterion of this classification alone showed that 31.4% of patients had renal dysfunction in stage of risk, 33.3% in stage of renal injury, and 21.6% in stage of renal failure. By the serum creatinine criterion, 27.5% were identified in the stage of risk, 3.9% in stage of injury and another 3.9% in stage of kidney failure. Conclusion: A high percentage of patients in the postoperative period of cardiac surgery (coronary artery bypass surgery and valve replacement) progressed to acute kidney injury. ResumoObjetivo: Identificar a ocorrência de lesão renal aguda em pós-operatório de cirurgia cardíaca. Métodos: Estudo de coorte prospectivo que incluiu 51 pacientes expostos a cirurgia de revascularização do miocárdio, troca valvar ou cirurgia combinada (revascularização do miocárdio e troca valvar), sem antecedentes de doença renal e de transplante renal e que foram acompanhados desde o pré-operatório até 72 horas de pós-operatório. Foi definido como lesão renal aguda o aumento de 0,3mg/dL em tempo menor ou igual a 48 horas ou aumento de 1,5 a 1,9 vez da creatinina basal, ou ainda redução do fluxo urinário <0,5mL/kg/h por 6 horas. Foi utilizada a classificação Kidney Disease: Improving Global Outcomes (KDIGO). Resultados: A classificação KDIGO sinalizou 92,2% dos pacientes com disfunção renal. O critério fluxo urinário dessa classificação isoladamente mostrou que 31,4% dos pacientes apresentaram disfunção renal no estágio de risco, 33,3% no estágio de lesão renal, e 21,6% no estágio de falência renal. Pelo critério creatinina sérica, foram identificados 27,5% no estágio de risco e, nos estágios de lesão e falência renal, foram identificados 3,9% pacientes em cada. Conclusão: Um percentual elevado de pacientes em pós-operatório de cirurgia cardíaca (revascularização miocárdica e troca valvar) progrediu com lesão renal aguda.

show abstract

Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Lesão renal aguda no pós-operatório de cirurgia cardíaca

Nascimento

Aguiar²,

Silva

et al. 2015

Acta paul. enferm.

View full text Add to dashboard Cite

show abstract

“…A metaanalysis in 2009 showed that mean CPB time and mean cross clamp time were significantly longer in patients who developed AKI. No safe time limit has been reported, however [99] .…”

Section: Intraoperative Risk Factorsmentioning

confidence: 99%

Serum creatinine role in predicting outcome after cardiac surgery beyond acute kidney injury

Najafi

2014

WJC

View full text Add to dashboard Cite

Serum creatinine is still the most important determinant in the assessment of perioperative renal function and in the prediction of adverse outcome in cardiac surgery. Many biomarkers have been studied to date; still, there is no surrogate for serum creatinine measurement in clinical practice because it is feasible and inexpensive. High levels of serum creatinine and its equivalents have been the most important preoperative risk factor for postoperative renal injury. Moreover, creatinine is the mainstay in predicting risk models and risk factor reduction has enhanced its importance in outcome prediction. The future perspective is the development of new definitions and novel tools for the early diagnosis of acute kidney injury largely based on serum creatinine and a panel of novel biomarkers.

show abstract

“…Более длительное время ИК связано с более высоким риском развития AKI, которое, в свою очередь, оказывает существенное влияние на общий уровень смертности (по данным отдель-ных исследований) [6]. основные результаты.…”

Section: Qing Chai Jin Liuunclassified

Prevention of Complications After Surgery With Cardiopulmonary Bypass

Радивилко¹

2016

Kompleks. probl. serdečno-sosud. zabol.

View full text Add to dashboard Cite

А. С. РАДИВИЛКО Федеральное государственное бюджетное научное учреждение «НИИ комплексных проблем сердечно-сосудистых заболеваний». Кемерово, РоссияИскусственное кровообращение является причиной системного воспалительного ответа. Существующие стратегии предупреж-дения постперфузионного системного воспаления не являются достаточно эффективными. Улучшение результатов лечения связано с изменением хирургической техники (коронарное шунтирование на работающем сердце), модификацией искусственного кровообра-щения и медикаментозной терапией. Настоящий дайджест по материалам современных систематических обзоров и метаанализов выполнен с целью обобщения основных ключевых моментов исследований по предотвращению постперфузионных осложнений.Ключевые слова: кардиохирургия, искусственное кровообращение, осложнения, систематический обзор, метаанализ. PREVENTION OF COMPLICATIONS AFTER SURGERY WITH CARDIOPULMONARY BYPASS А. S. RADIVILKO Federal State Budgetary Scientific Institution Research Institute for Complex Issues of Cardiovascular Diseases. Kemerovo, RussiaCardiopulmonary bypass is known to cause a systemic inflammatory response. Strategies to curb systemic inflammation have been previously described. However, none of them is adequate. Improved patient outcomes are strongly associated with surgical technique (offpump coronary artery bypass), cardiopulmonary bypass modalities or drug strategies. the aim of the present digest of modern systematic reviews and meta-analysis is to discuss the main key points about the main principles in cardiopulmonary bypass curbing inflammation.

show abstract

Association Between Postoperative Acute Kidney Injury and Duration of Cardiopulmonary Bypass: A Meta-Analysis

Cited by 104 publications

References 21 publications

Lesão renal aguda no pós-operatório de cirurgia cardíaca

Lesão renal aguda no pós-operatório de cirurgia cardíaca

Serum creatinine role in predicting outcome after cardiac surgery beyond acute kidney injury

Prevention of Complications After Surgery With Cardiopulmonary Bypass

Contact Info

Product

Resources

About