Association between physical activity dimensions and the risk of hypertension among middle and older adults: A cross-sectional study in China

Zhou, Linlin; Feng, Wei; Xiang, Na; Cheng, Ya; Ya, Xudong; Wang, Mingxia; Wang, Xingqi; Liu, Yujia

doi:10.3389/fpubh.2022.995755

Cited by 2 publications

(1 citation statement)

References 39 publications

(37 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many researches have demonstrated that several risks are linked to hypertension, including obesity, consumption of alcoholic beverages, sodium, homocysteine and vitamin intake (6)(7)(8). Homocysteine, an amino acid containing sulfur, is produced via the metabolic pathways of methionine, an essential amino acid obtained from dietary proteins (9).…”

Section: Introductionmentioning

confidence: 99%

Association between homocysteine and blood pressure in the NHANES 2003–2006: the mediating role of Vitamin C

Wu,

Ma,

Yang

et al. 2024

Front. Nutr.

View full text Add to dashboard Cite

BackgroundThe yearly escalation in hypertension prevalence signifies a noteworthy public health challenge. Adhering to a nutritious diet is crucial for enhancing the quality of life among individuals managing hypertension. However, the relationship between vitamin C and hypertension, as well as homocysteine, remains unclear.ObjectiveThe primary aim of this investigation was to scrutinize the potential mediating role of Vitamin C in the association between homocysteine levels and blood pressure, utilizing data extracted from the National Health and Nutrition Examination Survey (NHANES) database.MethodsA total of 7,327 participants from the NHANES 2003–2006 were enrolled in this cross-sectional survey. The main information was obtained using homocysteine, Vitamin C, systolic blood pressure (SBP) and diastolic blood pressure (DBP). Correlation analysis was used to assess the correlation between homocysteine, SBP, DBP and vitamin C. Linear regression analysis was utilized to determine the β value (β) along with its 95% confidence intervals (CIs). Mediation analysis was performed to investigate whether the relationship between homocysteine and blood pressure was mediated by Vitamin C, and to quantify the extent to which Vitamin C contributed to this association.ResultsThe results manifested that the homocysteine was positively associated with SBP (r = 0.24, p < 0.001) and DBP (r = 0.03, p < 0.05), while negatively correlated with Vitamin C (r = −0.008, p < 0.001). Vitamin C was found to be negatively associated with SBP (r = −0.03, p < 0.05) and DBP (r = 0.11, p < 0.001). Mediation effect analysis revealed that a partial mediation (indirect effect: 0.0247[0.0108–0.0455], p < 0.001) role accounting for 11.5% of total effect, among homocysteine and SBP. However, the mediating effect of Vitamin C between homocysteine and DBP was not statistically significant.ConclusionHypertension patients should pay attention to homocysteine and Vitamin C level. What is more, hypertension patients ought to formulate interventions for Vitamin C supplementation as well as homocysteine reduce strategies to lower blood pressure.

show abstract

Section: Introductionmentioning

confidence: 99%

Association between homocysteine and blood pressure in the NHANES 2003–2006: the mediating role of Vitamin C

Wu,

Ma,

Yang

et al. 2024

Front. Nutr.

View full text Add to dashboard Cite

show abstract

Enhanced body shape change coupled with PA is the key to hypertension management for urban residents

Wang,

Zhang,

Wang

et al. 2024

Public Health Nursing

View full text Add to dashboard Cite

The present study aimed to assess the relationship between body shape, physical activity (PA), and systolic blood pressure (SBP) and diastolic blood pressure (DBP). A novel visualization method was used to examine the effects of body shape combined with physical activity on hypertension. Data from 54,303 participants were obtained from the China Health and Nutrition Survey (CHNS) and analyzed using logistic regression models and standardized regression coefficients of linear models. These models were used to explore factors and effects of body shape indices and other parameters on SBP and DBP. The logistic regression model revealed that compared to transport‐related PA, the aggregated variables (weight and waist) were associated with a 2.44‐fold and 1.65‐fold increase in the risk of hypertension, respectively (p < .05). The average aggregated standardized coefficient of the linear model, based on 1000 bootstrap resamples, indicated that the Base Shape group had the strongest explanatory power for hypertension, followed by the Habits group. However, the explanatory power of the PA group was around 10 and 22 times lower than that of the Base Shape group for DBP and SBP, respectively (p < .05). These results demonstrate that increasing physical activity, with emphasizing a healthy body shape, and adopting positive lifestyle habits can effectively contribute to the prevention and control of hypertension.

show abstract

Association between physical activity dimensions and the risk of hypertension among middle and older adults: A cross-sectional study in China

Cited by 2 publications

References 39 publications

Association between homocysteine and blood pressure in the NHANES 2003–2006: the mediating role of Vitamin C

Association between homocysteine and blood pressure in the NHANES 2003–2006: the mediating role of Vitamin C

Enhanced body shape change coupled with PA is the key to hypertension management for urban residents

Contact Info

Product

Resources

About