Value-based health care has become a prime strategy in the US health care landscape to improve quality while controlling rising health care costs. Payors, including Medicare, have implemented alternative payment models (APMs) that tie quality and cost targets to reimbursement, but there is growing concern about how APMs affect vulnerable populations and the safety-net providers that care for them.The Centers for Medicare & Medicaid Services (CMS) recently released a radiation oncology (RO)-specific APM to disincentivize the use of highly compensated radiation modalities (prolonged fractionations, higher degree of complexity) over the use of equally effective, shorter, and simpler radiation treatments. The mandatory RO model randomizes practices into the APM by zip code and includes prospective 90-day episode-based payments for 16 cancer types. 1 Owing to implementation challenges and the uncertain effects of COVID-19, its launch was recently delayed to January 1, 2022. In the context of delays and a pandemic that has disproportionately taken the lives of poor people and racial minorities, we consider how the RO model can be improved to protect vulnerable populations from widening disparities.There are 3 main concerns about how the RO model may negatively affect vulnerable populations. First, analyses of similar APMs that incentivize value over volume suggest that they disproportionately penalize clinicians who take care of socially high-risk populations. For example, under