Association between Particulate Matter Exposure and Short-term Prognosis in Patients with Pneumonia

Chen, Chien-Chih; Huang, Jyun-Bin; Cheng, Shih-Yu; Wu, Keng‐Liang; Cheng, Fu-Jen

doi:10.4209/aaqr.2019.06.0293

Cited by 7 publications

(7 citation statements)

References 36 publications

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“…A report by WHO suggested approximately half of the populations of the 765 investigated cities in 67 countries were exposed to long-term PM 2.5 concentrations of at least 2.5 times higher than that of the WHO's air quality standard level, which may cause additional health risks [13]. A number of studies that focused on China's situation found that the incidence of mortality from COVID-19 is consistent with the previous findings in other infectious diseases including SARS-CoV-1, and there is a positive correlation with the exposure to a high concentration of pollutants exposure [14,15]. Research studies from other countries show similar findings in the relationship between COVID-19 and short-term PM 2.5 exposure [16][17][18].…”

Section: Introductionmentioning

confidence: 58%

“…This means that the countries with a larger population density and severe PM 2.5 pollution are more vulnerable to COVID-19 pandemic. Moreover, the concentrations of PM 2.5 used in this study were based on 2016 data, indicating possible effects of long-term exposure, which can impair lung function and increase the risk of viral infection [12][13][14][15]. Governments and health authorities of these regions should take more interventions to control the COVID-19 pandemic.…”

Section: Discussionmentioning

confidence: 99%

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COVID-19 Infection and Mortality: Association with PM2.5 Concentration and Population Density—An Exploratory Study

Wong

Kwan

et al. 2021

IJGI

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The novel coronavirus disease (COVID-19) has become a public health problem at a global scale because of its high infection and mortality rate. It has affected most countries in the world, and the number of confirmed cases and death toll is still growing rapidly. Susceptibility studies have been conducted in specific countries, where COVID-19 infection and mortality rates were highly related to demographics and air pollution, especially PM2.5, but there are few studies on a global scale. This paper is an exploratory study of the relationship between confirmed COVID-19 cases and death toll per million population, population density, and PM2.5 concentration on a worldwide basis. A multivariate linear regression based on Moran eigenvector spatial filtering model and Geographically weighted regression model were undertaken to analyze the relationship between population density, PM2.5 concentration, and COVID-19 infection and mortality rate, and a geostatistical method with bivariate local spatial association analysis was adopted to explore their spatial correlations. The results show that there is a statistically significant positive relationship between COVID-19 confirmed cases and death toll per million population, population density, and PM2.5 concentration, but the relationship displays obvious spatial heterogeneity. While some adjacent countries are likely to have similar characteristics, it suggests that the countries with close contacts/sharing borders and similar spatial pattern of population density and PM2.5 concentration tend to have similar patterns of COVID-19 risk. The analysis provides an interpretation of the statistical and spatial association of COVID-19 with population density and PM2.5 concentration, which has implications for the control and abatement of COVID-19 in terms of both infection and mortality.

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Section: Introductionmentioning

confidence: 58%

Section: Discussionmentioning

confidence: 99%

COVID-19 Infection and Mortality: Association with PM2.5 Concentration and Population Density—An Exploratory Study

Wong

Kwan

et al. 2021

IJGI

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“…The air pollution can increase the onset risk of pneumonia, including both hospitalization [ 9 , 10 ] and outpatient visit [ 11 ]. In addition, particulate matter (PM) can worsen the prognosis of pneumonia patients; according to Chen et al [ 12 ], it was associated with increased risk of invasive respiratory and/or vasopressor support and in-hospital mortality.…”

Section: Introductionmentioning

confidence: 99%

Short-term exposure to air pollution and hospital admission for pneumonia: a systematic review and meta-analysis

et al. 2021

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Background Air pollution is a major issue that poses a health threat worldwide. Although several studies investigated the adverse effects of air pollution on various diseases, few have directly demonstrated the effects on pneumonia. Therefore, we performed a systematic review and meta-analysis on the associations between short-term exposure of air pollutants and hospital admission or emergency room (ER) visit for pneumonia. Methods A literature search was performed using PubMed, Embase, and Web of Science up to April 10, 2020. Pooled estimates were calculated as % increase with 95% confidence intervals using a random-effects model. A sensitivity analysis using the leave-one-out method and subgroup analysis by region were performed. Results A total of 21 studies were included in the analysis. Every 10 μg/m3 increment in PM2.5 and PM10 resulted in a 1.0% (95% CI: 0.5–1.5) and 0.4% (95% CI: 0.2–0.6) increase in hospital admission or ER visit for pneumonia, respectively. Every 1 ppm increase of CO and 10 ppb increase of NO2, SO2, and O3 was associated with 4.2% (95% CI: 0.6–7.9), 3.2% (95% CI: 1.3–5.1), 2.4% (95% CI: − 2.0-7.1), and 0.4% (95% CI: 0–0.8) increase in pneumonia-specific hospital admission or ER visit, respectively. Except for CO, the sensitivity analyses yielded similar results, demonstrating the robustness of the results. In a subgroup analysis by region, PM2.5 increased hospital admission or ER visit for pneumonia in East Asia but not in North America. Conclusion By combining the inconsistent findings of several studies, this study revealed the associations between short-term exposure of air pollutants and pneumonia-specific hospital admission or ER visit, especially for PM and NO2. Based on the results, stricter intervention policies regarding air pollution and programs for protecting human respiratory health should be implemented.

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“…It is a challenge, especially in highly urbanized and industrialized territories. The influence of air pollution on the manifestation and exacerbation of respiratory diseases and mortality is well-documented [2][3][4][5][6]. Data from RACE PARIS registry suggest that even in such a healthy group as long-distance runners, air pollution may trigger major cardiac events during the race [2].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Short-Term Outdoor Air Pollution on Clinical Status and Prognosis of Hospitalized Patients with Coronary Artery Disease Treated with Percutaneous Coronary Intervention

Desperak

Szyguła‐Jurkiewicz

et al. 2022

JCM

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Background: The aim of this study was to determine the influence of acute exposure to air pollutants on patients’ profile, short- and mid-term outcomes of hospitalized patients with coronary artery disease (CAD) treated with coronary angioplasty. Methods: Out of 19,582 patients of the TERCET Registry, 7521 patients living in the Upper Silesia and Zaglebie Metropolis were included. The study population was divided into two groups according to the diagnosis of chronic (CCS) or acute coronary syndromes (ACS). Data on 24-h average concentrations of particulate matter with aerodynamic diameter <10 μm (PM10), sulfur dioxide (SO2), nitrogen monoxide (NO), nitrogen dioxide (NO2), and ozone (O3) were obtained from eight environmental monitoring stations. Results: No significant association between pollutants’ concentration with baseline characteristic and in-hospital outcomes was observed. In the ACS group at 30 days, exceeding the 3rd quartile of PM10 was associated with almost 2-fold increased risk of adverse events and more than 3-fold increased risk of death. Exceeding the 3rd quartile of SO2 was connected with more than 8-fold increased risk of death at 30 days. In the CCS group, exceeding the 3rd quartile of SO2 was linked to almost 2,5-fold increased risk of 12-month death. Conclusions: The acute increase in air pollutants’ concentrations affect short- and mid-term prognosis in patients with CAD.

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Association between Particulate Matter Exposure and Short-term Prognosis in Patients with Pneumonia

Cited by 7 publications

References 36 publications

COVID-19 Infection and Mortality: Association with PM2.5 Concentration and Population Density—An Exploratory Study

COVID-19 Infection and Mortality: Association with PM2.5 Concentration and Population Density—An Exploratory Study

Short-term exposure to air pollution and hospital admission for pneumonia: a systematic review and meta-analysis

The Impact of Short-Term Outdoor Air Pollution on Clinical Status and Prognosis of Hospitalized Patients with Coronary Artery Disease Treated with Percutaneous Coronary Intervention

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