Association Between Organic Dietary Choice During Pregnancy and Hypospadias in Offspring: A Study of Mothers of 306 Boys Operated on for Hypospadias

Christensen, Johnny; Asklund, Camilla; Skakkebæk, Niels E.; Jørgensen, Niels; Andersen, Helle Raun; Jørgensen, Troels Munch; Olsen, Lars Henning; Høyer, Anette Pernille; Moesgaard, J; Thorup, Jørgen; Jensen, Tina Kold

doi:10.1016/j.juro.2012.09.116

Cited by 42 publications

(37 citation statements)

References 25 publications

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“…No associations were seen for other organic food groups. The authors suggested as an explanation www.annualreviews.org • Exposure and Health Implicationsthat conventionally produced butter and cheese may contain more traces of pesticide residues than the organic equivalents, but they did not have measurements to support this (23).…”

Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

“…The studies included end points ranging from atopy, eczema, and/or respiratory disease (3,4,60,98,104) to reproductive anomalies in boys, (19,23), preeclampsia (106), sperm quality (1,54,57,62), cancer (15), and risk factors for cardiovascular disease (30). All except one study were observational.…”

Section: Health Benefits Linked To Organic Food Consumptionmentioning

confidence: 99%

“…One case-control study (23) and one prospective study (19) examined associations between organic food consumption and male reproductive development. The case-control study in Denmark comprised 306 mothers of boys who were operated on for hypospadias and 306 mothers of healthy boys.…”

Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

“…The case-control study in Denmark comprised 306 mothers of boys who were operated on for hypospadias and 306 mothers of healthy boys. This study suggested a protective association between hypospadias in the offspring and mother choosing the organic alternatives for butter and cheese (23). The mothers were asked to recall their intake of fruits, vegetables, milk, dairy products, eggs, and meat during pregnancy, and they were further asked whether organic alternatives were used often/sometimes or rarely/never.…”

Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

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Organic Food in the Diet: Exposure and Health Implications

Brantsæter

Ydersbond

Hoppin

et al. 2017

Annu. Rev. Public Health

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The market for organic food products is growing rapidly worldwide. Such foods meet certified organic standards for production, handling, processing, and marketing. Most notably, the use of synthetic fertilizers, pesticides, and genetic modification is not allowed. One major reason for the increased demand is the perception that organic food is more environmentally friendly and healthier than conventionally produced food. This review provides an update on market data and consumer preferences for organic food and summarizes the scientific evidence for compositional differences and health benefits of organic compared with conventionally produced food. Studies indicate some differences in favor of organic food, including indications of beneficial health effects. Organic foods convey lower pesticide residue exposure than do conventionally produced foods, but the impact of this on human health is not clear. Comparisons are complicated by organic food consumption being strongly correlated with several indicators of a healthy lifestyle and by conventional agriculture "best practices" often being quite close to those of organic.

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Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

Section: Health Benefits Linked To Organic Food Consumptionmentioning

confidence: 99%

Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

Section: Reproductive Anomalies In Boysmentioning

confidence: 99%

See 2 more Smart Citations

Organic Food in the Diet: Exposure and Health Implications

Brantsæter

Ydersbond

Hoppin

et al. 2017

Annu. Rev. Public Health

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“…Few studies have examined diet as a potential source of exposure to Endocrine disruptive chemicals (EDCs). Maternal choice of an organic alternative to food items during pregnancy was not associated with a decreased risk of hypospadias in the offspring [80].…”

Section: Diet and Pesticidesmentioning

confidence: 86%

Genetic and environmental factors in the aetiology of hypospadias

et al. 2015

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This article reviews the current evidence and knowledge of the aetiology of hypospadias. Hypospadias remains a fascinating anomaly of the male phallus. It may be an isolated occurrence or part of a syndrome or field defect. The increasing use of assisted reproductive techniques and hormonal manipulation during pregnancy may have been associated with an apparent rise in the incidence of hypospadias. Genetic studies and gene analysis have suggested some defects that could result in hypospadias. New light has also been thrown on environmental factors that could modulate candidate genes, causing altered development of the male external genitalia.

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Maternal Smoking, Alcohol, and Caffeine Exposures and Risk of Hypospadias

Carmichael

Shaw

2017

Birth Defects Research

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Maternal exposure to cigarette smoke was associated with reduced risk, and women who smoked, drank, and had low caffeine intake were at lowest risk. We do not interpret these results to suggest that these exposures have overall benefit to a pregnant woman or developing fetus. They may, however, offer clues to help us understand mechanisms that lead to hypospadias. Birth Defects Research 109:1127-1133, 2017. © 2017 Wiley Periodicals, Inc.

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Association Between Organic Dietary Choice During Pregnancy and Hypospadias in Offspring: A Study of Mothers of 306 Boys Operated on for Hypospadias

Cited by 42 publications

References 25 publications

Organic Food in the Diet: Exposure and Health Implications

Organic Food in the Diet: Exposure and Health Implications

Genetic and environmental factors in the aetiology of hypospadias

Maternal Smoking, Alcohol, and Caffeine Exposures and Risk of Hypospadias

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