Association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and metaanalysis

Cheong, Alex Jia Yang; Ho, Owen Tsung Wen; Wang, Sean Kang Xuan; Woon, Chang Yi; Yap, Ki Han; Ng, Kevin Joo Yang; Xu, Flora Wen Xin; See, Anna; Ng, Adele Chin Wei; Loh, Shaun; Chee, Soon-Phaik; Toh, Song Tar

doi:10.1016/j.survophthal.2022.11.006

Cited by 6 publications

(7 citation statements)

References 48 publications

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“…In mehreren Metaanalysen zeigte sich eine Assoziation zwischen OSAS und einem Glaukom 36 , 37 , 38 , 39 . Diese Assoziation konnte durch die Adjustierung für kardiovaskuläre und metabolische Risikofaktoren erklärt werden 40 .…”

Section: Obstruktive Schlafapnoeunclassified

“…Diese Assoziation konnte durch die Adjustierung für kardiovaskuläre und metabolische Risikofaktoren erklärt werden 40 . Cheong et al haben darüber hinaus in einer Metaanalyse Patienten mit und ohne OSAS hinsichtlich ihrer Gesichtsfeldveränderung, ihres Augeninnendrucks und ihrer retinalen Nervenfaserdicke untersucht: Hierbei zeigten sich bei OSAS-Patienten glaukomtypische Veränderungen des klinischen Befundes 38 . Der Anteil von OSAS-Patienten mit Glaukom war deutlich erhöht in der Subgruppe von Patienten mit Floppy-Eyelid-Syndrom (5,3% vs. 23,1%) 41 .…”

Section: Obstruktive Schlafapnoeunclassified

“…Several meta-analyses have shown an association between OSAS and glaucoma 36 , 37 , 38 , 39 . This association could be explained by the adjustment for cardiovascular and metabolic risk factors 40 .…”

Section: Obstructive Sleep Apneamentioning

confidence: 99%

“…This association could be explained by the adjustment for cardiovascular and metabolic risk factors 40 . Furthermore, in a meta-analysis, Cheong et al examined patients with and without OSAS with regard to their intraocular pressure, retinal nerve fiber thickness, and changes to their field of vision: here, patients with OSAS showed changes typical of glaucoma in their clinical findings 38 . The proportion of OSAS patients with glaucoma was significantly increased in the subgroup of patients with floppy eyelid syndromes (5.3% vs. 23.1%) 41 .…”

Section: Obstructive Sleep Apneamentioning

confidence: 99%

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Internistische Erkrankungen und Zusammenhang mit dem primären Offenwinkelglaukom

Voigt,

Grabitz,

Hoffmann

et al. 2024

Klin Monbl Augenheilkd

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ZusammenfassungDas primäre Offenwinkelglaukom (POWG) stellt eine neurodegenerative Erkrankung dar, in dessen Verlauf es zu einer glaukomatösen Optikusatrophie mit korrespondierenden Gesichtsfelddefekten kommt. In dieser Literaturübersicht werden Zusammenhänge zu internistischen Erkrankungen berichtet und die zugrunde liegende Pathophysiologie diskutiert. Hierbei wird die arterielle Hypertonie und Hypotonie, Diabetes mellitus, Dyslipidämien, obstruktive Schlafapnoe, chronischer Nierenerkrankung und Migräne diskutiert sowie Zusammenhänge mit der Einnahme von Medikamenten bei systemischen Erkrankungen näher betrachten.

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Section: Obstruktive Schlafapnoeunclassified

Section: Obstructive Sleep Apneamentioning

confidence: 99%

Section: Obstructive Sleep Apneamentioning

confidence: 99%

See 2 more Smart Citations

Internistische Erkrankungen und Zusammenhang mit dem primären Offenwinkelglaukom

Voigt,

Grabitz,

Hoffmann

et al. 2024

Klin Monbl Augenheilkd

View full text Add to dashboard Cite

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“…Up to 75% of patients with OSA have been found to have FES. [12][13][14] However, FES is often under-diagnosed due to nonspecific signs and symptoms such as pain, redness, and epiphora. 15,16 Aponeurotic ptosis may occur in patients with OSA, with or without concurrent FES.…”

mentioning

confidence: 99%

Obstructive Sleep Apnea Associated With Increased Failure Rate of Ptosis Repair

Nirmalan,

Tran,

Tailor

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: This study investigates how Obstructive sleep apnea (OSA) affects the outcomes of ptosis repair. We hypothesized that patients with OSA have an increased rate of reoperation after ptosis repair. Methods: This retrospective cohort study included patients age >18 from the Mayo Clinic who underwent ptosis repair by levator advancement or Müller muscle-conjunctiva resection between 2018 and 2021. Outcomes were measured at 1 to 3 months of follow-up with surgical failure defined as asymmetry or unsatisfactory eyelid height requiring revision surgery within 1 year. Results: A total of 577 patients met the inclusion criteria. There was a statistically significant difference in surgical failure between patients with OSA and those without (20.5% vs. 13.1%, p = 0.02). Patients with OSA showed a statistically significant difference in risk of revision by a factor of 1.70 (95% CI: 1.06–2.07). Revisions were attributed to unsatisfactory eyelid height in 72.6% of patients and eyelid asymmetry in 21.1%. All patients who had revision surgery had satisfactory outcomes. On logistic regression analysis, when adjusting for age and sex, OSA was significantly associated with ptosis revision (p = 0.007). Conclusions: OSA increases risk of surgical failure and need for revision surgery in patients undergoing blepharoptosis repair but is not a sole risk factor.

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Observations on the association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and meta-analysis

Chan,

Lee,

Tweedie

et al. 2024

Survey of Ophthalmology

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Association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and metaanalysis

Cited by 6 publications

References 48 publications

Internistische Erkrankungen und Zusammenhang mit dem primären Offenwinkelglaukom

Internistische Erkrankungen und Zusammenhang mit dem primären Offenwinkelglaukom

Obstructive Sleep Apnea Associated With Increased Failure Rate of Ptosis Repair

Observations on the association between obstructive sleep apnea and floppy eyelid syndrome: A systematic review and meta-analysis

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