Association between muscle strength and the cardiopulmonary status of individuals living with HIV/AIDS

Abstract

OBJECTIVE:The purpose of this study was to compare aerobic function [anaerobic threshold (%V˙O2-AT), respiratory compensation point (%V˙O2-RCP) and peak oxygen uptake (V˙O2peak)] between physically active patients with HIV/AIDS and matched controls and to examine associations between disease status, poor muscle strength, depression (as estimated by the profile of mood states questionnaire) and the aerobic performance of patients.METHODS:Progressive treadmill test data for %V˙O2-AT (V-slope method), RCP and (V˙O2peak) were compared between 39 male patients with HIV/AIDS (age 40.6±1.4 years) and 28 male controls (age 44.4±2.1 years) drawn from the same community and matched for habitual physical activity. Within-patient data were also examined in relation to CD4+ counts (nadir and current data) and peak isokinetic knee torque.RESULTS:AT, RCP and (V˙O2peak) values were generally similar for patients and controls. Within the patient sample, binary classification suggested that AT, RCP and (V˙O2peak) values were not associated with either the nadir or current CD4+ count, but treadmill test variables were positively associated with peak isokinetic knee torque.CONCLUSION:The aerobic performance of physically active patients with HIV/AIDS is generally well conserved. Nevertheless, poor muscle strength is observed in some HIV/AIDS patients, which is associated with lower anaerobic power and (V˙O2peak), suggesting the possibility of enhancing the aerobic performance of patients with weak muscles through appropriate muscle-strengthening activities.

Cardiorespiratory fitness levels and moderators in people with HIV: A systematic review and meta-analysis

“…After screening titles and application of the eligibility criteria, 21 studies (Baigis et al, 2002;Cade et al, 2003;Cade et al, 2013;Cutrono et al, 2015;Dolan et al, 2006;Ezema et al, 2014;Hand et al, 2008;Jaggers et al, 2014;MacArthur et al, 1993;Mangona et al, 2015;Mapstone et al, 2014;Mutimura et al, 2008;Neto et al, 2016;Oursler et al, 2009;Perna et al, 1999;Ramírez-Marrero et al, 2014;Raso et al, 2013;Smith et al, 2001;Sullivan et al, 2014;Terry et al, 2006;Thoni et al, 2002) were eligible for inclusion in the meta-analysis. (n=31) and sub-maximal (n=5) exercise tests.…”

Physical activity correlates in people living with HIV/AIDS: a systematic review of 45 studies

“…Out of 84 potentially eligible studies, 45 were included in this review [37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80]. The search strategy and reasons for exclusion are shown in Figure 1.…”

Physical activity levels and perceived benefits and barriers to physical activity in HIV-infected women living in the deep south of the United States†

“…Similar to our results, physical complaints such as being tired or having low energy levels were identified as barriers to PA (Roos et al, 2015). Reduced VO2peak associated with poor muscle strength has been reported in PLWH and may account for this finding (Raso et al, 2013). Past exercise experiences with exercise (e.g.…”