Association between maternal exposure to particulate matter and premature birth

Abstract

The objective of this time-series study carried out in São José dos Campos, a southeastern Brazilian city, between 01. 01.2005 and 31.12.2009, was to estimate the role of maternal exposure to air pollutants and preterm births. Preterm newborns of mothers aged between 18 and 34 years, with at least eight years of schooling, singleton pregnancies and whose delivery was vaginal were included in the study. Logistic regression was used to estimate the role of particulate matter, ozone and sulfur dioxide on preterm delivery with lags of zero up to 30 days. Exposure to particulate matter was associated significantly with preterm newborns in lags of 0, 1 and 3 days; but no association was found between cumulative maternal exposure in lags of 7, 15 and 30 days and the outcome. Maternal exposure to particulate matter therefore has an acute effect on preterm births in a medium-sized Brazilian town. Associação entre a exposição materna ao material particulado e parto prematuro RESUMOO objetivo deste estudo de séries temporais desenvolvido em São José dos Campos, localizada sudeste do Brasil, entre 01.01.2005 e 31.12.2009, foi estimar o papel da exposição materna aos poluentes do ar e partos prematuros. Recém-nascidos prematuros de mães com idade entre 18 e 34 anos, com pelo menos oito anos de escolaridade, gestações únicas e cujo parto foi vaginal foram incluídos no estudo. A regressão logística foi utilizada para estimar o papel da exposição ao material particulado, ozônio e dióxido de enxofre em trabalho de parto prematuro com defasagens de zero até 30 dias. Exposição ao material particulado esteve associada significativamente com partos prematuros em lag 0, 1 e 3, mas não houve associação entre a exposição materna acumulada sete, 15 e 30 dias antes do parto e o desfecho. Assim, a exposição materna ao material particulado tem um efeito agudo em recém-nascidos prematuros em uma cidade de brasileira de porte médio.Palavras-chave: poluentes do ar, parto prematuro, regressão logística, material particulado, poluição do ar. 28Thaiza Agostini Córdoba de Lima et al.Rev. Ambient. Água vol. 9 n.

Maternal exposure to benzene and toluene and preterm birth. A longitudinal study

“…18 Other comparisons with the Brazilian literature are very difficult, given the scarcity of studies on the effect of maternal exposure to air pollutants and occurrence of premature delivery. In a single study conducted by Lima et al, 19 a significant association between premature delivery and exposure to PM 10 was found on the day of delivery (lag 0), the day before delivery (lag 1) and three days prior to delivery. However, a different approach was used in their study.…”