Association between malnutrition, clinical parameters and health-related quality of life in elderly hospitalized patients with Parkinson’s disease: A cross-sectional study

Abstract

This study aimed to explore the association between malnutrition, clinical parameters, and health-related quality of life in elderly hospitalized patients with Parkinson's disease (PD). MethodsCross-sectional study of 92 hospitalized elderly patients with PD (mean age 73.6 ± 6.7 years) without dementia. The Mini Nutritional Assessment (MNA) was used to evaluate nutritional status. Motor impairment and non-motor symptoms burden (Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale [MDS-UPDRS], Non-Motor Symptoms Questionnaire, and Hoehn & Yahr staging), depression (Becks Depression Inventory-II), and health-related quality of life (PD quality of life Questionnaire-39) were assessed. ResultsEvery second patient was malnourished or at risk of malnutrition. In the multivariable analysis, male gender, longer disease duration, higher Hoehn & Yahr and depression were associated with total MNA score. Besides non-motor symptoms and motor impairment, malnutrition was an independent predictor of poor health-related quality of life. In the multivariate analysis, malnutrition had a statistically significant effect on emotional well-being, mobility, social support, stigmatization, and cognition. The strongest association was found between malnutrition and emotional well-being. ConclusionElderly male persons with longer PD duration and higher disease stages are more likely to be malnourished or at risk for malnutrition. Malnutrition was mainly associated with poor emotional well-being, suggesting that treatment of depression and anxiety beside diet and physical activity can help improving nutrition status in these subjects. The MNA should not

Prevalence of Malnutrition in Patients with Parkinson’s Disease: A Systematic Review

“…Mini Nutritional Assessment is used for assessing the nutritional status of patients. There were 22 studies included in which MNA assessments were conducted [ 10 , 11 , 12 , 16 , 17 , 18 , 19 , 21 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 ]. There was a total of 2713 participants, of which 39.2% were female and 60.8% were male.…”

“…We took into consideration 49 studies [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ] in which BMI was assessed, resulting in 5727 patients, 57.3% of whom were men and 40.9% of whom were women. The lowest reported mean BMI was 17.84 kg/m 2 [ ...…”

Cannabis in Parkinson’s Disease — the patient’s perspective versus clinical trials: a systematic literature review

“…One potentially positive aspect of marijuana treatment may be an increase in weight [31]. Although generally seen as a drawback, this may actually benefit advanced PD patients with malnutrition, something which is observed in 50% of PD patients [45].…”

Stockpiling and food worries: Changing habits and choices in the midst of COVID-19 pandemic

“…COVID-19 is noted to have continuous effect on food security, destabilizing agriculture value chains, and these problems are predicted to be severe in low-income countries that already face food insecurity [ 12 ]. In such countries, food insecurity that may result from the COVID-19 may compound wide spread of malnutrition [ 12 ] and wide spread of incidence of chronic diseases [ 13 , 14 ].…”