Association between malnutrition and stages of sarcopenia in geriatric rehabilitation inpatients: RESORT

Verstraeten, Laure M G; Wijngaarden, J.P. van; Pacifico, Jacob; Reijnierse, Esmee M.; Meskers, Carel G.M.; Maier, Andrea B.

doi:10.1016/j.clnu.2021.02.007

Cited by 41 publications

(33 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, GNRI was independently and significantly related to quadriceps thickness in this study. Considering malnutrition is closely related to sarcopenia [ 35 , 36 ], this result supported these previous results.…”

Section: Discussionsupporting

confidence: 89%

Relationship between muscle mass and fraction of intramuscular adipose tissue of the quadriceps in older inpatients

et al. 2022

View full text Add to dashboard Cite

Background In 2021, the International Society of Physical and Rehabilitation Medicine (ISPRM) special interest group on sarcopenia included the quadriceps thickness assessed with ultrasound image as an indicator of muscle mass in the diagnosis criteria of sarcopenia. If quadriceps echo intensity of older inpatients is to be a strong predictor of quadriceps thickness, muscle quality of the quadriceps may be estimated by the muscle mass when diagnosing sarcopenia using the criteria of ISPRM. Objective This study aimed to examine the association between muscle mass and fraction of intramuscular adipose tissue of the quadriceps in older inpatients. Methods This cross-sectional study included 399 inpatients aged ≥ 65 years. Primary outcomes were muscle mass and fraction of intramuscular adipose tissue of the quadriceps. Images were acquired using a B-mode ultrasound. Muscle mass and fraction of intramuscular adipose tissue of the quadriceps were assessed based on the muscle thickness and echo intensity, respectively. A multiple regression analysis (forced entry method) was performed to confirm whether quadriceps echo intensity was related to quadriceps thickness even after adjusting for other factors. Results In the multiple regression analyses for both male and female models, quadriceps echo intensity (male: β = − 0.537, p < 0.001; female: β = − 0.438, p < 0.001), Geriatric Nutritional Risk Index (male: β = 0.236, p < 0.001; female: β = 0.213, p < 0.001), and subcutaneous fat thickness of the thigh (male: β = 0.197, p < 0.001; female: β = 0.248, p < 0.001) were independently and significantly associated with quadriceps thickness. Conclusions Our results show that there is a negative and significant association between muscle mass and fraction of intramuscular adipose tissue in older inpatients. Muscle quality of the quadriceps in older inpatients may be estimated to some extent by the muscle mass.

show abstract

Section: Discussionsupporting

confidence: 89%

Relationship between muscle mass and fraction of intramuscular adipose tissue of the quadriceps in older inpatients

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The prevalence of the Co-MS in our study was higher than that in a Spanish study conducted on a post-acute geriatric rehabilitation unit with a smaller sample size and used the EWGSOP criteria for sarcopenia and ESPEN diagnosis criteria for malnutrition (n = 88, 14.8%) [13]. However, the prevalence in our study was nearly identical to an Australian study which investigated the geriatric rehabilitation of inpatients (n = 506, 23%), and employed EWGSOP2 criteria and GLIM criteria for sarcopenia and malnutrition, respectively [14]. Since the EWGSOP2 criteria uses the same criteria (low SMI and low handgrip strength) as the AWGS 2019 criteria, the results of the Australian study can be comparable to ours.…”

Section: Prevalence Of the Coexistence Of Malnutrition And Sarcopeniacontrasting

confidence: 61%

“…The aetiology of sarcopenia is associated with disease burden, inappropriate nutritional intake, and inactivity in addition to ageing, and it shares the same feature as malnutrition, which is a loss of muscle mass [2]. Consequently, the coexistence of malnutrition and sarcopenia (Co-MS) is prevalent and is receiving growing interest [11][12][13][14]. In an acute care setting, 4.9% of the patients had Co-MS, and it was associated with higher mortality in hospitalised older patients than malnutrition or sarcopenia alone [12].…”

Section: Introductionmentioning

confidence: 99%

“…In an acute care setting, 4.9% of the patients had Co-MS, and it was associated with higher mortality in hospitalised older patients than malnutrition or sarcopenia alone [12]. Additionally, only two studies investigated the prevalence of Co-MS in geriatric rehabilitation patients [13,14]. A Spanish study conducted in a post-acute care unit showed that 14.8% of older patients had Co-MS [13].…”

Section: Introductionmentioning

confidence: 99%

“…A Spanish study conducted in a post-acute care unit showed that 14.8% of older patients had Co-MS [13]. Another study that examined Australian geriatric rehabilitation inpatients indicated that 23%, 1.3% and 13% of the malnourished patients had probable sarcopenia, non-severe sarcopenia, and severe sarcopenia, respectively [14]. Increasing awareness of Co-MS should be prioritised, because these two conditions are often overlooked and undertreated in clinical practice and have aforementioned adverse effects on mortality [12,15,16].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and Associated Factors of Coexistence of Malnutrition and Sarcopenia in Geriatric Rehabilitation

Nishioka¹,

Matsushita²,

Yamanouchi³

et al. 2021

Nutrients

View full text Add to dashboard Cite

Malnutrition and sarcopenia often coexist in rehabilitation patients, although they are often overlooked and undertreated in clinical practice. This cross-sectional study aimed to clarify the prevalence of the coexistence of malnutrition and sarcopenia (Co-MS) and its associated factors in convalescent rehabilitation wards in Japan. Consecutive patients aged ≥ 65 years in convalescent rehabilitation wards between November 2018 and October 2020 were included. Malnutrition and sarcopenia were determined by the Global Leadership Initiative on Malnutrition (GLIM) criteria and the Asian Working Group for Sarcopenia (AWGS 2019) criteria, respectively. Patients who presented both with malnutrition and sarcopenia were classified as Co-MS. Potentially associated factors included age, sex, days from onset to admission of rehabilitation wards, reason for admission, pre-morbid functional dependency, comorbidity, activities of daily living, swallowing ability, and oral function and hygiene. The prevalence of malnutrition, sarcopenia, and Co-MS was calculated. Binary logistic regression analyses were performed to compute odds ratios (ORs) and the 95% confidence interval (CI) of possible associated factors for each condition. Overall, 601 patients were eligible for the analysis (median 80 years old, 355 female patients, 70% cerebrovascular disease). Co-MS, malnutrition, and sarcopenia were found in 23.5%, 29.0%, and 62.4% of the enrolled patients, respectively. After adjustment, onset–admission interval (OR = 1.04; 95%CI = 1.02 to 1.06), hospital-associated deconditioning (OR = 4.62; 95%CI = 1.13 to 18.8), and swallowing ability (Food Intake LEVEL Scale) (OR = 0.83; 95%CI = 0.73 to 0.93) were identified as independent explanatory factors of Co-MS. In conclusion, Co-MS was prevalent in geriatric rehabilitation patients; thus, healthcare professionals should be aware of the associated factors to detect the geriatric rehabilitation patients who are at risk of both malnutrition and sarcopenia, and to provide appropriate treatments.

show abstract

Sarcopenia and frailty in inflammatory bowel disease: Emerging concepts and evidence

Neelam,

Sharma,

Sharma

2024

JGH Open

View full text Add to dashboard Cite

Sarcopenia is a condition marked by progressive loss of skeletal muscle mass and function while frailty is a multidimensional concept characterized by diminished physiological reserve and increased vulnerability to stressors. Both of these were previously considered as related to aging and shown to impact the quality of life and carry prognostic significance. Emerging data show that both sarcopenia and frailty carry similar relevance in chronic illness. Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract and malnourishment, both of which contribute to the development of sarcopenia by increasing protein breakdown and reducing protein synthesis. The coexistence of frailty further compounds the clinical complexity of IBD patients. Published evidence suggests a bidirectional association with IBD contributing to muscle wasting, while the resultant sarcopenia and frailty could further exacerbate the disease course. Sarcopenia and frailty are independently associated with adverse outcomes, including hospitalizations, increased surgical interventions, and surgical complications. As therapeutic strategies for IBD evolve, understanding the nuanced relationship between inflammatory bowel disease, sarcopenia, and frailty is crucial for devising holistic management. Comprehensive care should encompass not only disease‐modifying therapies but also interventions targeting frailty and sarcopenia, as they have been shown to have a significant impact not only on the disease course but also on the quality of life. Future research could focus on further elucidating underlying mechanisms, simple screening strategies, and developing targeted interventions to improve the overall quality of life for individuals grappling with the complex interplay of IBD, sarcopenia, and frailty.

show abstract

Association between malnutrition and stages of sarcopenia in geriatric rehabilitation inpatients: RESORT

Cited by 41 publications

References 60 publications

Relationship between muscle mass and fraction of intramuscular adipose tissue of the quadriceps in older inpatients

Relationship between muscle mass and fraction of intramuscular adipose tissue of the quadriceps in older inpatients

Prevalence and Associated Factors of Coexistence of Malnutrition and Sarcopenia in Geriatric Rehabilitation

Sarcopenia and frailty in inflammatory bowel disease: Emerging concepts and evidence

Contact Info

Product

Resources

About