Association between lower urinary tract symptoms (LUTS) and obsessive‐compulsive disorders (OCD) in women: A study based on urodynamic findings and micturition problem

Abstract

This study focused on women with chronic lower urinary tract symptoms (LUTS) who simultaneously suffered from obsessive-compulsive disorder (OCD) to evaluate the association between micturition abnormality and OCD.Methods: A cohort case study was conducted on 128 women with chronic LUTS who visited the academic clinic from 2012 to 2018. The participants with a history of OCD were grouped together, whereas the other group consisted of those with no psychiatric issues. Data were analyzed using the Kolmogorov-Smirnov test and also the nonparametric Kruskal-Wallis and χ 2 tests. Results:The participants with OCD had a lower mean age (41.7 vs. 48.8 years) and longer symptom duration than the control group. Moreover, voiding phase problems were more prevalent among OCD patients (mean voiding score: 9.3 vs. 6.9). Urge urinary incontinence (UUI) was the most common type of urinary incontinence in OCD patients, and the most important urodynamic study finding was bladder outlet obstruction (45% and 17% in the OCD and control groups, respectively). Voiding disorders resulted in chronic renal failure in two patients (3.12%). It was shown that bladder outlet obstruction (odds ratio (OR) 4.43, 95% confidence interval [CI] 1.53-12.78, p = 0.006] was the strongest predictor of OCD and stress urinary incontinence (OR 0.20, 95% CI 0.07-0.53, p < 0.001) was the best protector against OCD. Conclusion:The findings revealed that chronic LUTS was related to voiding dysfunction and urodynamic abnormality in OCD patients. These disorders may be categorized as somatoform disorder that requires appropriate treatments.

The cumulative effect of unmet social needs on noncancerous genitourinary conditions and severity of lower urinary tract symptoms

“…For example, obsessive compulsive disorder (OCD) has been associated with LUTS, including urge symptoms and voiding dysfunction, suggesting a psychosocial contribution to LUTS. 19 Similarly, OAB patients report higher anxiety as compared with age-matched controls, as well as more problems with sleep, fatigue, and depression, and this effect is likely bidirectional in nature. 20 The interplay between LUTS and genitourinary conditions, unmet social needs, and psychosocial burden is an area to consider for further investigation in the future.…”

“…Additionally, increased psychosocial burden has been associated with LUTS. For example, obsessive compulsive disorder (OCD) has been associated with LUTS, including urge symptoms and voiding dysfunction, suggesting a psychosocial contribution to LUTS 19 . Similarly, OAB patients report higher anxiety as compared with age‐matched controls, as well as more problems with sleep, fatigue, and depression, and this effect is likely bidirectional in nature 20 .…”

The design and evaluation of a quick checklist for urodynamic quality control: A prospective single‐center small sample study

“…Previous studies have shown that acute and chronic psychological stress leads to changes in micturition frequency, interval, and volume. [30][31][32] Patients with interstitial cystitis were not suggested to undergo UDS. Normal urination process requires the coordination of physiological, environmental, and psychological factors.…”

Obsessive‐compulsive disorder and men's health. Part 1: Recognition and diagnosis

“…It is known to commonly manifest with OCD, in which case the primary OCD symptom usually involves the obsession that the bladder feels full and may be associated with an obsessive fear of ‘accidentally wetting oneself’ ( ie harm). Associated compulsions include mental checking for the ‘full bladder’ sensation and frequent visits to the toilet to attempt to urinate, often at night (as per OAB) 18 . One study investigating the association between OAB and OCD reported that female patients with OAB were more likely to have OCD traits than the non‐OAB control group participants (odds ratio 5.47; p =0.001).…”

“…Associated compulsions include mental checking for the 'full bladder' sensation and frequent visits to the toilet to attempt to urinate, often at night (as per OAB). 18 One study investigating the association between OAB and OCD reported that female patients with OAB were more likely to have OCD traits than the non-OAB control group participants (odds ratio 5.47; p=0.001). Checking compulsions were the commonest associated OCD symptoms.…”