Association between Low Fruit and Vegetable Consumption and Colorectal Polyps in Thailand

Supachai, Kannika; Siripongpreeda, Bunchorn; Soonklang, Kamonwan; O-Pad, Napatsawan; Krohkaew, Kanlayanee; Suebwongdit, Chanisara; Panaiem, Suchada

doi:10.31557/apjcp.2020.21.9.2733

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…Red meat is classified by the IARC as “probably carcinogenic” to humans. In addition, vegetable consumption was significantly higher in controls than in cases with multiple polyps, which also agrees with previous studies ( 46 , 47 ). For example, two studies, one cohort and one case-control, found that the risk of colorectal polyps is increased with lower consumption of cooked green vegetables ( 39 ) and fruits and vegetables ( 40 ), respectively.…”

Section: Discussionsupporting

confidence: 92%

Adherence to Mediterranean diet and its association with multiple colonic polyps of unknown origin: a case-control study

Bujanda-Miguel,

Martínez-Roca,

García-Heredia

et al. 2023

Front. Nutr.

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IntroductionMultiple colonic polyps do not have a genetic origin in most patients, and the cause of this phenotype remains elusive. Environmental factors, such as diet, could be related to this phenotype. Our aim was to investigate the relationship between the adherence to Mediterranean diet and multiple colonic polyps of unknown origin.MethodsA case-control pilot study was carried out with a sample of 38 individuals, including 23 cases with more than 10 adenomatous or serrated polyps from the national multicenter project EPIPOLIP and 15 healthy controls with normal colonoscopy. A validated Spanish version of the MEDAS questionnaire was administered to cases and controls.ResultsAdherence to Mediterranean diet was higher in controls than in patients with multiple colonic polyps (MEDAS score: 8.6 ± 1.4 vs. 7.0 ± 1.6; p = 0.01). Optimal overall adherence to the Mediterranean diet pattern was significantly higher among the controls than among cases (MEDAS score >9: 46% vs. 13%; OR 0.17; 95% CI 0.03–0.83). Non-optimal adherence to the Mediterranean diet acts as a risk factor for developing colorectal cancer derived from colorectal polyps.ConclusionOur results suggest that environmental factors play a role in the pathogenesis of this phenotype.

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Section: Discussionsupporting

confidence: 92%

Adherence to Mediterranean diet and its association with multiple colonic polyps of unknown origin: a case-control study

Bujanda-Miguel,

Martínez-Roca,

García-Heredia

et al. 2023

Front. Nutr.

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“…Our research evidenced the higher consumption of fruits as a protective factor in the development of CRC, which is consistent with a series that recently demonstrated the importance of fruit and vegetable intake as protective factors for this type of cancer [21]. Similarly, a diet poor in fruits and the presence of high-risk adenoma polyps were significantly associated with increasing the probability to develop CRC [22]. Since both vegetables and fruits are considered good sources of fiber, folic acid, B vitamins, minerals, and antioxidants, their protective properties could lie in the decreased gastrointestinal transit time, which leads to reduced concentrations of carcinogenic compounds [23].…”

Section: Discussionsupporting

confidence: 92%

Association of Family History and Life Habits in the Development of Colorectal Cancer: A Matched Case-Control Study in Mexico

Díaz¹,

Álvarez-Bañuelos

Robaina-Castellanos

et al. 2021

IJERPH

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Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and, as such, is important for public health. The increased incidence of this neoplasm is attributed to non-modifiable controls such as family history and modifiable variable behavioral risk factors involved in lifestyle like diets in Mexico. The presence of these factors is unknown. Therefore, the aim of this study was to evaluate family history and lifestyle factors associated with developing colorectal cancer in a Mexican population. Descriptive statistics and multivariate logistic regression were used to estimate the adjusted odds ratios (OR), as well as the 95% confidence intervals (CI). In this paper, significant differences were demonstrated between cases and controls. A family history of cancer (FHC) increased the probability of CRC [OR = 3.19 (95% CI: 1.81–5.60)]. The area of urban residence was found to be a protective factor compared to the rural area. This was also the case for frequent consumption of fruits [OR = 0.49 (95% CI: 0.28–0.88)], the frequent consumption of beef [OR = 2.95 (95% CI: 1.05–8.26)], pork [OR = 3.26 (95% CI: 1.34–7.90)], and region-typical fried food [OR = 2.79 (95% CI (1.32–5.89)]. These results provide additional evidence supporting the association of some CRC risk factors with family history of cancer, low fruit consumption, high consumption of red meat, and fried foods typical of the region of México. It is important to establish intervention methods, as well as genetic counseling to relatives of patients with CRC.

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“…The results of this study also revealed that the increase in the consumption of vegetables and fruits significantly reduced the likelihood of developing colorectal polyps. The association between dietary fiber and colon cancer has been under investigation for three decades; however, no definite association has been recognized [ 36 , 37 ]. Aune et al reported that a higher proportion of fiber in everyday dietary regimens can reduce the recurrence rate of colorectal adenomas [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

The frequency of colorectal lesions in the first-degree relatives of patients with colorectal lesions among PERSIAN Guilan Cohort Study population (PGCS)

Matin,

Joukar,

Maroufizadeh

et al. 2024

BMC Gastroenterol

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Background This study aimed to investigate the frequency of colorectal lesions in the first-degree relatives of patients with colorectal lesions among the Prospective Epidemiological Research Studies in Iran (PERSIAN )Guilan Cohort Study (PGCS) population. Methods In this cross-sectional study, 162 first-degree relatives with a history of colorectal lesions were randomly selected from 52 participants in PGCS. All subjects underwent total colonoscopy by a gastroenterologist, and a pathologist evaluated colorectal biopsies. Also, individuals’ demographic information, clinical data, and dietary habits were recorded. Results The mean age of the participants was 56.55 ± 7.04. Of 86 colon polyps, 52 neoplastic and 34 non-neoplastic polyps were observed in 56 patients (34.6%). Individuals with age > 60 years had 3.29-fold increased odds of developing colorectal polyps (OR = 3.29, 95% CI: 1.13–9.56, P = 0.029). The smokers were 2.73 times more susceptible to developing colorectal polyps than non-smokers (OR = 2.73, 95% CI: 1.24–6.02, P = 0.013). Moreover, consumption of vegetables more than three times per day was associated with decreased OR of colorectal polyp development (OR = 0.43, CI: 0.19–0.98, P = 0.045). Conclusions Considering the high prevalence of neoplastic colorectal polyps among the first-degree relatives of patients with colorectal lesions, early screening is recommended for individuals with a family history of colorectal lesions.

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Association between Low Fruit and Vegetable Consumption and Colorectal Polyps in Thailand

Cited by 6 publications

References 22 publications

Adherence to Mediterranean diet and its association with multiple colonic polyps of unknown origin: a case-control study

Adherence to Mediterranean diet and its association with multiple colonic polyps of unknown origin: a case-control study

Association of Family History and Life Habits in the Development of Colorectal Cancer: A Matched Case-Control Study in Mexico

The frequency of colorectal lesions in the first-degree relatives of patients with colorectal lesions among PERSIAN Guilan Cohort Study population (PGCS)

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