Association between intracranial aneurysm and meningiomas: An integrative survival Analysis with identification of prognostic factors

Souza, Matheus Rodrigues de; Fagundes, Caroline Ferreira; Rabelo, Ní­collas Nunes; Teixeira, Manoel Jacobsen; Figueiredo, Eberval Gadelha

doi:10.1016/j.clineuro.2020.106128

Cited by 4 publications

(6 citation statements)

References 34 publications

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“…These findings suggest a complex relationship between tumors and aneurysms that warrants further research. [ 6 , 11 ] Herein, we present a rare case of a female patient harboring two giant lesions, located in different intracranial compartments.…”

Section: Introductionmentioning

confidence: 99%

“…ese findings suggest a complex relationship between tumors and aneurysms that warrants further research. [6,11] Herein, we present a rare case of a female patient harboring two giant lesions, located in different intracranial compartments. the left frontotemporal region and a right infratentorial solid extra axial mass, suggestive of a tentorial meningioma [Figures 1 and 2].…”

Section: Introductionmentioning

confidence: 99%

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A rare case of a right infratentorial meningioma and a left giant posterior communicating thrombosed aneurysm

Lara-Olivas,

Sangrador-Deitos,

Villalobos-Díaz

et al. 2023

Surgical Neurology International

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Background: Giant intracranial aneurysms cause symptoms due to mass effect and can mimic other lesions in imaging studies. The coexistence of tumors and aneurysms is relatively rare, with meningiomas being the predominant tumors found in such cases. The relationship between these two entities is complex and represent a neurosurgical challenge. Case Description: A 61-year-old woman presented with intermittent headache, vertigo, right peripheral facial palsy, hearing loss, and left hemiparesis. Magnetic resonance imaging revealed two lesions: a supratentorial paraclinoid lesion in the left frontotemporal region and a right infratentorial extra-axial mass, suggestive of a meningioma. The patient underwent a two-staged surgical intervention to address both lesions. Conclusion: In this particular case, the lesions were located on different sides and in different cranial compartments, making it even rarer.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A rare case of a right infratentorial meningioma and a left giant posterior communicating thrombosed aneurysm

Lara-Olivas,

Sangrador-Deitos,

Villalobos-Díaz

et al. 2023

Surgical Neurology International

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“…IA may rupture or leak, and the ruptured IA could lead to bleeding in brain tissues, causing hemorrhagic stroke. 3,4 It is estimated that more than 25% of IA patients will die after IA rupture, and IA complications cause deaths in another 25% of patients within 6 months after rupture. [4][5][6] The ruptured IA is usually treated with surgical clipping or less invasive endovascular coiling.…”

Section: Introductionmentioning

confidence: 99%

“…3,4 It is estimated that more than 25% of IA patients will die after IA rupture, and IA complications cause deaths in another 25% of patients within 6 months after rupture. [4][5][6] The ruptured IA is usually treated with surgical clipping or less invasive endovascular coiling. 7 However, these two treatments might reduce blood flow to the brain and bleeding in the brain.…”

Section: Introductionmentioning

confidence: 99%

LncRNA SAMMSON Overexpression Suppresses Vascular Smooth Muscle Cell Proliferation via Inhibiting miR-130a Maturation to Participate in Intracranial Aneurysm

Pan

Gao

Wan

et al. 2021

NDT

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Background MiR-130a is a recently identified critical player in vascular smooth muscle cell (VSMC) proliferation, which participates in intracranial aneurysm (IA). However, the involvement of miR-130a in IA and its upstream regulator are unknown. Our preliminary sequencing analysis revealed a close correlation between miR-130a and lncRNA SAMMSON across IA samples. Therefore, we further studied the crosstalk between SAMMSON and miR-130a in IA. Methods SAMMSON and miR-130a expression were measured using RT-qPCR. SAMMSON subcellular location was analyzed with nuclear fractionation assay. Their direct interaction was explored with RNA pull-down assay. The role of SAMMSON in miR-130a maturation was studied with overexpression analysis. VSMC cell proliferation was analyzed with BrdU assay. Results SAMMSON and premature miR-130a were deregulated in IA, while mature miR-130a was upregulated in IA. SAMMSON is localized in both the nucleus and cytoplasm, and direct interaction between SAMMSON and miR-130a was observed. SAMMSON overexpression suppressed miR-130a maturation in VSMCs and reduced the enhancing effects of miR-130a on VSMC cell proliferation. Conclusion SAMMSON is overexpressed in IA and suppresses VSMC proliferation via inhibiting miR-130a maturation.

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“…Despite recent advances in diagnostic technology, the coexistence of an intracranial tumor and a cerebral aneurysm is still uncommon, with estimated incidence rates ranging from 0.2% to 7.7%. [1][2][3] Previous research 1 suggests that the majority of aneurysms are located outside the tumor, and the relationship and pathogenesis of coexisting aneurysms with intracranial tumors are unknown. Hormonal influences from the tumor, 4 gene mutations or loss of gene expression, 2 and increased hemodynamic stresses on the feeding vessel to the tumor 5 are all possible pathogeneses of aneurysm development.…”

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confidence: 99%

Successful treatment with urgent revascularization and parent artery occlusion for a ruptured intratumoral aneurysm following prior meningioma surgery: illustrative case

Okuyama

Kurisu

Hokari

et al. 2023

Journal of Neurosurgery: Case Lessons

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BACKGROUND An intratumoral aneurysm encased within the associated intracranial tumor is rare, and hemorrhage caused by its rupture is even more rare. While urgent and adequate surgical treatment is important, the treatment can be difficult given the limited understanding of this rare condition. OBSERVATIONS A 69-year-old man who had undergone meningioma surgery 30 years prior presented with a disturbance in consciousness. Magnetic resonance imaging revealed massive intracerebral and subarachnoid hemorrhage. A round, partially calcified mass, which was diagnosed as recurrent meningioma, was also observed. Subsequent cerebral angiography revealed that the source of the hemorrhage was an intratumoral aneurysm in the dorsal internal carotid artery (ICA) encased within the recurrent meningioma. Urgent surgical ICA trapping and high-flow graft bypass were conducted. The postoperative course was uneventful, and he was referred to another hospital for rehabilitation. LESSONS This is the first case report of a ruptured intratumoral aneurysm being treated with urgent combined revascularization and parent artery trapping surgery. This surgical approach may be a feasible treatment option for such a challenging condition. Additionally, this case highlights the importance of diligent long-term follow-up after skull-base surgery, as minor intraoperative vascular wall injury may trigger the development and rupture of an intracerebral aneurysm.

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Association between intracranial aneurysm and meningiomas: An integrative survival Analysis with identification of prognostic factors

Cited by 4 publications

References 34 publications

A rare case of a right infratentorial meningioma and a left giant posterior communicating thrombosed aneurysm

A rare case of a right infratentorial meningioma and a left giant posterior communicating thrombosed aneurysm

LncRNA SAMMSON Overexpression Suppresses Vascular Smooth Muscle Cell Proliferation via Inhibiting miR-130a Maturation to Participate in Intracranial Aneurysm

Successful treatment with urgent revascularization and parent artery occlusion for a ruptured intratumoral aneurysm following prior meningioma surgery: illustrative case

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