“…Furthermore, certain mutations within the upstream region (UR) of embA are associated with EMB resistance (Cui et al, 2014;Brossier et al, 2015;Zhao et al, 2015). However, the presence of these mutations in embAB was also observed in EMBsusceptible isolates (Shi et al, 2011;Zhao et al, 2015;Li et al, 2016;Sun et al, 2018). Besides, there are no mutations within the particular genes responsible for EMB resistance in some EMB-resistant isolates, implying the involvement of other resistance mechanisms (Sharma and Bisht, 2017;Sharma et al, 2018).…”