2016
DOI: 10.3892/etm.2016.3113
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Association between hypoxemia and anemia following arthroplasty: A pilot clinical study

Abstract: Hypoxia and anemia are common complications following joint arthroplasty. Whether hypoxia indicates that a patient is anemic and whether anemia causes a decline in arterial oxygen pressure accompanied by hypoxemia are not completely understood. The aim of the present study was to determine the association between hypoxemia and anemia following arthroplasty. A total of 135 patients who underwent arthroplasty at the China-Japan Friendship Hospital between January and May 2013 were retrospectively analyzed. The p… Show more

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Cited by 3 publications
(3 citation statements)
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“…Additionally, radiation‐induced hypoxia and inflammation may intensify one another, leading to a vicious cycle of hypoxia and inflammation. Low Hb levels have been linked to tissue hypoxia and increased expression of genes involved in hypoxia, profibrotic molecule synthesis (TGF‐β1, PDGFC, and PAI‐1), and the fibrosis process (LOX, P4HA1, and P4HB; Gao et al, 2016). As a result, it is fair to assume that the increased incidence of RIT in patients with low Hb (41.9% vs. 7.3%) and anemia (37.6% vs. 4.4%) in our study may be at least partially explained by the complicated interactions between hypoxia, intensified inflammation and hastened fibrosis processes (Garrido et al, 2015; Somay, Yilmaz, Topkan, Kucuk, Haksoyler, et al, 2022).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Additionally, radiation‐induced hypoxia and inflammation may intensify one another, leading to a vicious cycle of hypoxia and inflammation. Low Hb levels have been linked to tissue hypoxia and increased expression of genes involved in hypoxia, profibrotic molecule synthesis (TGF‐β1, PDGFC, and PAI‐1), and the fibrosis process (LOX, P4HA1, and P4HB; Gao et al, 2016). As a result, it is fair to assume that the increased incidence of RIT in patients with low Hb (41.9% vs. 7.3%) and anemia (37.6% vs. 4.4%) in our study may be at least partially explained by the complicated interactions between hypoxia, intensified inflammation and hastened fibrosis processes (Garrido et al, 2015; Somay, Yilmaz, Topkan, Kucuk, Haksoyler, et al, 2022).…”
Section: Discussionmentioning
confidence: 99%
“…Additionally, radiation-induced hypoxia and inflammation may intensify one another, leading to a vicious cycle of hypoxia and inflammation. Low Hb levels have been linked to tissue hypoxia and increased expression of genes involved in hypoxia, profibrotic molecule synthesis (TGF-β1, PDGFC, and PAI-1), and the fibrosis process (LOX, P4HA1, and P4HB; Gao et al, 2016). As a result, it is fair to assume that the increased incidence of RIT in patients with low Hb (41.9% vs.…”
Section: Ta B L Ementioning
confidence: 99%
“…Hypoxemia was defined as a desaturation nadir of SpO 2 <90%, and severe hypoxemia was defined as SpO 2 <70%. [13] Patients with acute stroke are at risk of respiratory compromise due to aspiration, upper airway obstruction, hypoventilation, and neurogenic pulmonary edema. The combination of poor perfusion and hypoxemia exacerbates and extends ischemic brain injury and has been associated with worse outcomes.…”
Section: Introductionmentioning
confidence: 99%