Association between Hyperhomocysteinemia and Hypertensive Retinopathy in a Chinese Han Population

Zhong, Zhigang; Liu, Jie

doi:10.1080/02713683.2021.1894581

Cited by 2 publications

(2 citation statements)

References 18 publications

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“…Ischemic cerebrovascular disease is characterized by concealed and diverse clinical manifestations, which not only cause stroke but also significantly affect the cognition, emotion, and daily living ability of patients. The incidence rate is on the rise [ 25 ]. In short, ischemic cerebrovascular disease is a common problem that affects the health of the elderly.…”

Section: Related Workmentioning

confidence: 99%

Diagnostic Value of Hcy Combined with Blood Pressure Variability Index in the Severity of Hypertension Complicated with CSVD and Its Correlation with Cognitive Function and CysC Expression

Liu¹,

Liu²,

Zhang³

et al. 2022

Journal of Healthcare Engineering

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This paper explores the diagnostic value of Hcy combined with the blood pressure variability index in the severity of hypertension complicated with CSVD and its correlation with cognitive function and CysC expression. 200 patients with ischemic small cerebral vessels are selected as the research object. According to the MRI findings, they are divided into 48 cases of white matter lesions (WML), 44 cases of lacunar infarction (LI), 44 cases of enlarged perivascular spaces (EPVs), and 46 cases in the mixed group (referring to two or more types of ischemic cerebrovascular disease on imaging). Different cognitive domains of different types of ischemic cerebrovascular diseases are analyzed. The risk factors of cognitive decline in patients with ischemic cerebrovascular disease are analyzed by univariate analysis and multivariate logistic regression analysis. There is an ancestral correlation between serum Hcy and CSVD, which is an independent risk factor for CSVD.

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Section: Related Workmentioning

confidence: 99%

Diagnostic Value of Hcy Combined with Blood Pressure Variability Index in the Severity of Hypertension Complicated with CSVD and Its Correlation with Cognitive Function and CysC Expression

Liu¹,

Liu²,

Zhang³

et al. 2022

Journal of Healthcare Engineering

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show abstract

“…Literatürde HR ile HH ilişkisinin araştırıldığı tek çalışmada, HH tanılı 128 hastada, sağlıklı kontrollere kıyasla anlamlı artmış HR riskinin mevcut olduğu ve serum total homosistein seviyesinde 1 µmol/L'lik bir artışın HR riskinde %9'luk bir artışla ilişkili olduğu bildirilmiştir. [49]…”

Section: Hiperhomosisteineminin Hipertansif Retinopati Gelişimi üZeri...unclassified

Hyperhomocysteinemia, Hyperlipidemia and Retina

2023

Güncel Retina (Current Retina)

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Hyperhomocysteinemia is a disease with an increase in the plasma level of homocysteine, an intermediate of methionine metabolism, and predisposes to thrombosis. It is a well-established risk factor for occlusive cardiovascular illnesses and has been linked to ocular pathologies such as retinal vascular disorders, age-related macular degeneration, and most notably ectopia lentis. Lipids compose approximately 20% of the dry weight of the retina. Apart from their structural significance, lipids also serve a critical function in providing the necessary energy for the metabolic needs of the retina. Hyperlipidemia is described as an abnormally high level of blood cholesterol and triglycerides and is a major risk factor for atherosclerosis. It may increase the risk of retinal vascular disorders secondary to atherosclerosis-like processes in the retina. Through the inflammatory process they generate, hyperhomocysteinemia and hyperlipidemia may also contribute to the progression of retinal vascular disorders such as diabetic and hypertensive retinopathy and retinopathy of prematurity.

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Association between Hyperhomocysteinemia and Hypertensive Retinopathy in a Chinese Han Population

Cited by 2 publications

References 18 publications

Diagnostic Value of Hcy Combined with Blood Pressure Variability Index in the Severity of Hypertension Complicated with CSVD and Its Correlation with Cognitive Function and CysC Expression

Diagnostic Value of Hcy Combined with Blood Pressure Variability Index in the Severity of Hypertension Complicated with CSVD and Its Correlation with Cognitive Function and CysC Expression

Hyperhomocysteinemia, Hyperlipidemia and Retina

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