Association between histo-blood group antigens and Pseudomonas aeruginosa-associated diarrheal diseases

Chuang, Chih-Hsien; Wang, Yi-Hsin; Chang, Hsin-Ju; Chen, Chyi‐Liang; Chiu, Cheng-Hsun

doi:10.1016/j.jmii.2022.12.008

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…The study also found that patients with blood group A were susceptible to Pseudomonas aeruginosa, consistent with literature reports [15]. Meanwhile, patients https://doi.org/10.1017/S0950268823000432 Published online by Cambridge University Press with the A&AB blood group are also susceptible to Pseudomonas aeruginosa, as blood groups A and AB do not contain antibody A, so it is speculated that the biological principle may be related to the natural bacteriocidal effect of antibody A on Pseudomonas aeruginosa.…”

Section: Discussionsupporting

confidence: 92%

“…Glycoconjugate structures on RBCs serve various functions [ 7 ], including serving as receptors for bacteria and parasites [ 8 , 9 ], foreign ligands, viruses, transporters, channels, structural proteins, adhesion molecules, enzymes, and structural proteins. ABO blood groups are statistically or physiologically associated with a variety of non-infectious diseases – such as acute kidney injury (AKI) [ 10 ], acute respiratory distress syndrome (ARDS) [ 11 ], myocardial disease [ 12 ], pancreatic cancer [ 13 ], embolism [ 14 ] – and infectious diseases [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

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ABO blood groups and nosocomial infection

Zhong¹,

Wang²,

Xiao³

et al. 2023

Epidemiol. Infect.

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Nosocomial infection (NI) harms patients' health. Timely identifying the high-risk groups of NIs plays a vital role in preventing and control of NIs. Therefore, it is crucial to investigate whether the ABO blood group is a risk factor for NI to identify and protect high-risk populations. In this study, the patients of NI and non-infection from January 2016 to July 2022 were matched by the propensity score matching (PSM) method and analysed stratified by NI pathogens and NI sites. Finally, a logistic regression model was used to analyse the matched datasets. The study found that: Patients with the B&AB blood group were susceptible to Escherichia coli (OR=1.783, P=0.039), patients with the A blood group were susceptible to Staphylococcus aureus (OR=2.539, P=0.019), and Pseudomonas aeruginosa (OR=5.724, P=0.003). Patients with the A&AB blood group were susceptible to Pseudomonas aeruginosa (OR=4.061, P=0.008). Patients with the AB blood group were vulnerable to urinary tract infection (OR=13.672, P=0.019), patients with the B blood group were susceptible to skin and soft tissue infection (OR=2.418, P=0.016), and patients with the B&AB blood group were vulnerable to deep incision infection (OR=4.243, P=0.043). Summarily, The patient's blood group is a susceptibility factor for common NI pathogens and NI sites, which is vital for identifying high-risk groups for NIs and developing targeted prevention and control measures for NIs.

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

ABO blood groups and nosocomial infection

Zhong¹,

Wang²,

Xiao³

et al. 2023

Epidemiol. Infect.

View full text Add to dashboard Cite

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“…Nosocomial infections, one of the most challenging and common infections to treat due to their restricted susceptibility to antimicrobial agents, are predominantly caused by Pseudomonas aeruginosa ( P. aeruginosa ) [ 1 , 2 ]. P. aeruginosa is a prevalent pathogen responsible for infections among patients undergoing post-operative care [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

A Label-Free Fluorescent Amplification Strategy for High-Sensitive Detection of Pseudomonas aeruginosa based on Protective-EXPAR (p-EXPAR) and Catalytic Hairpin Assembly

Huang,

Zhang,

Liu

et al. 2024

J. Microbiol. Biotechnol.

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This study presents a fluorescent mechanism for two-step amplification by combining two widely used techniques, exponential amplification reaction (EXPAR) and catalytic hairpin assembly (CHA). Pseudomonas aeruginosa ( P. aeruginosa ) engaged in competition with the complementary DNA in order to attach to the aptamer that had been fixed on the magnetic beads. The unbound complementary strand in the liquid above was utilized as a trigger sequence to initiate the protective-EXPAR (p-EXPAR) process, resulting in the generation of a substantial quantity of short single-stranded DNA (ssDNA). The amplified ssDNA can initiate the second CHA amplification process, resulting in the generation of many double-stranded DNA (dsDNA) products. The CHA reaction was initiated by the target/trigger DNA, resulting in the release of G-quadruplex sequences. These sequences have the ability to bond with the fluorescent amyloid dye thioflavin T (ThT), generating fluorescence signals. The method employed in this study demonstrated a detection limit of 16 CFU/ml and exhibited a strong linear correlation within the concentration range of 50 CFU/ml to 10 5 CFU/ml. This method of signal amplification has been effectively utilized to create a fluorescent sensing platform without the need for labels, enabling the detection of P. aeruginosa with high sensitivity.

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