Association between giant cell arteritis and thyroid dysfunction in a “real life” population

Yavne, Yarden; Tiosano, Shmuel; Watad, Abdulla; Comaneshter, Doron; Shoenfeld, Yehuda; Cohen, Arnon D; Amital, Howard

doi:10.1007/s12020-017-1347-9

Cited by 11 publications

(6 citation statements)

References 35 publications

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“…The main limitation is that the diagnoses of both GCA and pericarditis were not based on standardized diagnostic criteria, but rather on diagnostic labels drawn from CHS physician reports. However, previous studies have supported the high validity of the diagnoses in this database . In this study, past diagnosis of pericarditis represented either acute pericarditis or chronic pericarditis, or pleural effusion (or a combination), which may arise from different etiologies.…”

Section: Discussionmentioning

confidence: 50%

“…Although PMR is closely related to GCA, it was not included in this study due to the low documentation rate of this comorbidity alongside GCA in the CHS database. In a previous study we discussed this discrepancy, which is due to registration and documentation habits in real life, rather than lower‐than‐expected rates of PMR …”

Section: Discussionmentioning

confidence: 98%

“…However, previous studies have supported the high validity of the diagnoses in this database. 40 In this study, past diagnosis of pericarditis represented either acute pericarditis or chronic pericarditis, or pleural effusion (or a combination), which may arise from different etiologies. Another possible disadvantage of this study is that it was designed as a cross-sectional study, so it was impossible to determine whether pericarditis occurred before, during, or after the diagnosis of GCA.…”

Section: Study Limitationsmentioning

confidence: 95%

“…In a previous study we discussed this discrepancy, which is due to registration and documentation habits in real life, rather than lower-than-expected rates of PMR. 40…”

Section: Study Limitationsmentioning

confidence: 99%

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Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

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Background Giant cell arteritis (GCA) is an inflammatory disease of unknown etiology affecting adults age > 50 years. GCA (also known as temporal arteritis) is a vasculitis of large and medium‐size vessels that involves the extracranial branches of the carotid artery. Common manifestations include constitutional symptoms, headache, jaw claudication, scalp tenderness, and vision loss. Cardiac involvement in GCA is considered to be as low as 5%, and < 30 cases of pericarditis among GCA patients have been reported in the literature. The aim of this study was to evaluate the association between GCA and pericarditis by conducting a cross‐sectional study utilizing the database of the largest healthcare provider in Israel. Hypothesis GCA is associated with pericarditis. Methods The proportion of past documentation of pericarditis among patients diagnosed with GCA was compared with that of their age‐ and sex‐matched controls. Univariate analysis was performed using the χ2 and t tests; multivariate analysis was performed using logistic regression. Results The study included 4329 GCA patients and 21 611 controls. GCA patients had higher rates of cardiovascular risk factors. Pericarditis was observed in 53 GCA patients and 72 controls (1.22% vs 0.33%, respectively; P < 0.001), significantly higher among GCA patients in comparison with controls. A significant interaction was found between GCA, pericarditis, and young age (<70 years). Conclusions The study showed an independent association between GCA and pericarditis, especially among young patients. Proper screening should be applied whenever a suspicion arises as to the existence of comorbidity in patients with either disease.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 98%

Section: Study Limitationsmentioning

confidence: 95%

“…In a previous study we discussed this discrepancy, which is due to registration and documentation habits in real life, rather than lower-than-expected rates of PMR. 40…”

Section: Study Limitationsmentioning

confidence: 99%

See 2 more Smart Citations

Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

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“…En los pacientes con ACG, las masas solo se localizaron en mama u ovario 48 . Se han reportado asociaciones de ACG con tiroideopatía, con enfermedad coronaria (la cual es una de las causas de mortalidad en estos pacientes además de las infecciones), con enfermedad inflamatoria intestinal y con cáncer, entre otras [54][55][56][57][58][59][60] .…”

Section: Discussionunclassified

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2020

RFEM

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Pu bli ca ción tri mes tral. Re ser va dos to dos los de re chos. Nin gu na par te de es ta pu bli ca ción pue de ser re pro du ci da en for ma o me dio al gu no, elec tró ni co o me cá ni co, in clu yen do fo to co pias, gra ba cio nes y otros sis te mas de in for ma ción sin la au to ri za ción expresa por parte de los editores. La responsabilidad por los juicios, opiniones, pun tos de vista o traducciones expresados en los artículos publicados corresponde ex clusivamente a sus autores..

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