Association between G316A growth hormone polymorphism and economic traits in pigs

Abstract

The association between G316A growth hormone polymorphism and quantitative traits was investigated in an F2 population of pigs. Association analyses were performed using a statistical model that included genotype, sex, batch and sex by genotype interaction as fixed effects and sire as random effect. The polymorphism was associated with the number of right teats (p = 0.03), heart weight (p = 0.04), lung weight (p = 0.05), carcass length determined by the Brazilian carcass classification method (p = 0.04), picnic shoulder weight (p = 0.07), jowl weight (p = 0.01), pH 24 h after slaughtering (p = 0.03) and drip loss (p = 0.01). Interaction between genotype and sex was observed for six performance traits. The additive effect was significant (p < 0.10) for heart weight, jowl weight and pH 24 h after slaughtering. The effect of dominance was significant (p < 0.05) for number of right teats, heart weight, carcass length, picnic shoulder weight and pH 24 h after slaughtering. This study shows that the growth hormone gene is a potential candidate for investigating the phenotypic variation of quantitative traits in pigs, and suggests its possible application in breeding programs.

Mapeamento de QTL nos cromossomos 1, 2, 3, 12, 14, 15 e X em suínos: características de carcaça e qualidade de carne

“…Faria et al (2006), na mesma população utilizada no presente estudo, encontraram um polimorfismo no gene GH (G316A) associado com o número de tetas direitas (p=0,03), peso do coração (p=0,04), peso do pulmão (p=0,05), comprimento de carcaça (p=0,04), peso total da paleta (p=0,07), peso da papada (p=0,01), pH medido 24 horas postmortem (p=0,03) e perda por gotejamento (p=0,01). No presente estudo, encontrou-se QTL para algumas dessas carcaterísticas associadas ao gene GH em diferentes cromossomos.…”

“…Para construção do mapa de ligação dos seis cromossomos autossômicos e o sexual X, utilizou-se o software CRIMAP versão 2.4 (Green et al, 1990). Os dados de genótipo, fenótipo e o mapa de ligação gerados foram submetidos ao software GridQTL (Seaton et al, 2006) para detecção de QTL.…”

Association between insulin-like growth factor I (IGF-I) microsatellite polymorphisms and important economic traits in pigs

“…The experimental F2 population, the phenotypes, and the DNA extraction procedures were fully described by Band et al (2005a,b), Faria et al (2006), and Peixoto et al (2006).…”

Quantitative trait loci for carcass, internal organ and meat quality traits on porcine chromosomes 16, 17 and 18

“…Details of the experimental F2, the phenotypes and the DNA extraction procedures used have been described by Band et al (2005a,b) and Faria et al (2006). Eleven primer pairs for microsatellite markers distributed on SSC16 (S0006, SW977, SW2517, SW1897), SSC17 (SW24, SW2142, S0359, SW2427) and SSC18 (SW1984, S0120, S0177) were used.…”