Association between executive function and outcome measure of treatment in therapeutic community among cocaine dependent individuals

Vergara-Moragues, Esperanza; Verdejo-García, Antonio; Lozano, Óscar; Santiago‐Ramajo, Sandra; González‐Sáiz, Francisco; Espinosa, Patricia Betanzos; Garcı́a, Miguel Pérez

doi:10.1016/j.jsat.2017.04.014

Cited by 24 publications

(12 citation statements)

References 40 publications

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“…Moreover, uncontrolled for self‐reported impulsivity, response inhibition deficits seemed less severe in patients who had missed a research appointment. This seems to contrast studies that found cognitive‐motivational problems (in particular, response inhibition deficits measured with cognitive computer tasks) were related to poorer treatment completion in substance‐abusing and forensic patients (Fishbein et al, 2009; Vergara‐Moragues et al, 2017). The mixed results may be explained by the different treatment outcomes across studies.…”

Section: Discussioncontrasting

confidence: 61%

“…Results of these studies are mixed. In some studies, response inhibition deficits were increased in patients who dropped‐out of treatment, and negatively related to progress as indicated by clinical professionals (Fishbein et al, 2009; Vergara‐Moragues et al, 2017). Yet, in other studies no associations with treatment drop‐out were found (Smeijers et al, 2017; Stevens et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

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Cognitive‐motivational, interpersonal, and behavioral functioning in relationship to treatment and research engagement in forensic patients with ADHD

et al. 2020

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Objectives To provide more insight into treatment and research responsivity in offenders with attention‐deficit hyperactivity disorder (ADHD). Method Via self‐reports and patients' scores on cognitive computer tasks, it was examined whether poorer cognitive‐motivational, interpersonal, and behavioral functioning were related to treatment no‐shows, longer treatment time duration intervals, and no‐show at the research appointment in 52 forensic outpatients with ADHD (Mage = 35.3, SD = 9.38). Treatment adherence was tracked for 10 appointments after research participation. Results Regression analyses showed that higher self‐reported impulsivity was associated with research no‐show, and more alcohol use with longer treatment time intervals. Yet, self‐reported delay aversion was associated with fewer treatment no‐shows, and, uncontrolled for alcohol use, impulsivity was associated with shorter treatment time intervals in a subsample of patients. Conclusions These preliminary results indicate that externalizing behaviors increase the risk for nonadherence in forensic ADHD patients, but that cognitive‐motivational problems also motivate patients to be more engaged.

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Section: Discussioncontrasting

confidence: 61%

Section: Introductionmentioning

confidence: 99%

Cognitive‐motivational, interpersonal, and behavioral functioning in relationship to treatment and research engagement in forensic patients with ADHD

et al. 2020

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“…These findings could have important clinical implications for the understanding of differential behavioral patterns of SCD and IC and the consequent development of successful treatment strategies. Knowledge of the cognitive profile provides valuable information concerning cognitive strengths and weaknesses that are important in a clinical context 36,38,90 . In this way, improving our knowledge of the neuropsychological deficits associated with specific routes of administration could help identify better pharmacological and psychotherapeutic interventions 90,91 .…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, cognitive deficits have been associated with an early dropout of addiction treatments 35 . Specifically, cognitive flexibility and inhibitory control had been related as predictors of maintenance in treatments, as perseverative errors being a predictor for early dropout 36,37 . Therefore, knowledge of the cognitive functioning of patients on addiction treatment has been proposed as much as significant information to predict compliance and maintenance of treatment 38 and to adapt interventions 39 .…”

Section: Introductionmentioning

confidence: 99%

Structural and functional signatures of executive deficits after early use of cocaine depend upon route of administration

Fuente¹,

Vignaga²,

Prado³

et al. 2020

Preprint

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Background: There is growing evidence linking cocaine consumption with a broad spectrum of neurocognitive deficits. Despite of evidence suggesting that the route of administration should be taken into account to assess the short and long term effects of cocaine consumption, to our knowledge no study to date has characterized clinically relevant neuropsychological variables along with physiological variables separately in populations of individuals with histories of smoked cocaine dependence (SCD) and insufflated cocaine hydrochloride dependence (ICD). Methods: The present study examined a sample of (a) 25 participants who fulfilled criteria for SCD, (b) 22 participants who fulfilled criteria for ICD, and (c) 25 healthy controls matched by age, gender, education, and socioeconomic status. An exhaustive neuropsychological battery was used to assess different cognitive domains (attention, executive functions, fluid intelligence, memory, language and social cognition). We complemented this neuropsychological assessment with the acquisition and analysis of structural (MRI) and functional (fMRI) neuroimaging data. Results: Different routes of administration led to equally different profiles of neurocognitive impairment, with the SCD group being specifically associated with deficits in attention and executive functions. Consistent with risk models, executive function-attention deficit is better explained for age and age onset of consumption initiation. SCD also presented reduced grey matter density relative to ICD in the bilateral caudate, a key area for executive functions and attention. Connectivity between left caudate and inferior frontal regions mediates performance-structure association. Conclusions: Cocaine routes of administration are associated to a differential profile that may not be due direct effects of stimulant action but also driven by cognitive and biological differences in key executive functioning and attention areas. This point the critical importance of the routes of administration. This information could inform clinical management and should be taken into account in clinical research.

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“…Iowa Gambling Task (Bechara, Damasio, Damasio, & Anderson, 1994). Se administró la versión computarizada en castellano de la Iowa Gambling Task (IGT) y se utilizaron las instrucciones propuestas en el manual de uso de la prueba (Verdejo et al, 2004;Vergara-Moragues et al, 2017). La IGT es una prueba neuropsicológica para simular la toma de decisiones de la vida real, con componente emocional, que es ampliamente utilizada en la investigación de la cognición y la emoción.…”

Section: Instrumentos De Evaluaciónunclassified

Diferencias entre hombres y mujeres en los procesos de toma de decisiones en pacientes con trastornos relacionados con sustancias

Piñón-Blanco¹,

Vergara-Moragues

Torres-Rincón

et al. 2018

RLP

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Resumen Los trastornos relacionados con sustancias (TRS) pueden cursar con alteraciones neuropsicológicas que afectan las actividades de la vida diaria de una persona. El objetivo principal de este trabajo es estudiar el proceso de la toma de decisiones en pacientes con TRS y analizar si hay diferencias entre hombres y mujeres. Se administró una versión computarizada de la Iowa Gambling Task (IGT) a una muestra total de 101 pacientes con TRS que solicitaron tratamiento ambulatorio, 81 hombres (80,2%) y 20 mujeres (19,8%). Los resultados muestran una alteración en la toma de decisiones. Asimismo, se observó un peor rendimiento en el grupo de los hombres en la toma de decisiones en comparación con el grupo de las mujeres. Estos datos comprueban la importancia de tener en cuenta el sexo a la hora del diagnóstico e intervención en personas con TRS. Se precisan estudios futuros que profundicen en estas diferencias.

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Association between executive function and outcome measure of treatment in therapeutic community among cocaine dependent individuals

Cited by 24 publications

References 40 publications

Cognitive‐motivational, interpersonal, and behavioral functioning in relationship to treatment and research engagement in forensic patients with ADHD

Cognitive‐motivational, interpersonal, and behavioral functioning in relationship to treatment and research engagement in forensic patients with ADHD

Structural and functional signatures of executive deficits after early use of cocaine depend upon route of administration

Diferencias entre hombres y mujeres en los procesos de toma de decisiones en pacientes con trastornos relacionados con sustancias

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