Association between dietary selenium intake and severe abdominal aortic calcification in the United States: a cross-sectional study

Dong, Weiwei; Liu, Xiaobai; Ma, Lu; Yang, Zhiyong; Ma, Chunyan

doi:10.1039/d3fo02631k

Cited by 2 publications

(2 citation statements)

References 36 publications

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“…Selenium works as an antioxidant in the body by preventing vascular cell damage. In a recent study, a higher dietary selenium intake was negatively associated with severe abdominal aorta calcification incidence in CKD patients [ 117 ]. The selenium content of foods can vary considerably depending on the geographic area; nuts, oats, seeds, mushrooms, beans, and eggs can be good sources.…”

Section: Bioactive and Senolytic Food And Vascular Calcification In Ckdmentioning

confidence: 99%

Food to Prevent Vascular Calcification in Chronic Kidney Disease

Moldovan,

Rusu,

Potra

et al. 2024

Nutrients

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Vascular calcification (VC) is a consequence of chronic kidney disease (CKD) which is of paramount importance regarding the survival of CKD patients. VC is far from being controlled with actual medication; as a result, in recent years, diet modulation has become more compelling. The concept of medical nutritional therapy points out the idea that food may prevent or treat diseases. The aim of this review was to evaluate the influence of food habits and nutritional intervention in the occurrence and progression of VC in CKD. Evidence reports the harmfulness of ultra-processed food, food additives, and animal-based proteins due to the increased intake of high absorbable phosphorus, the scarcity of fibers, and the increased production of uremic toxins. Available data are more supportive of a plant-dominant diet, especially for the impact on gut microbiota composition, which varies significantly depending on VC presence. Magnesium has been shown to prevent VC but only in experimental and small clinical studies. Vitamin K has drawn considerable attention due to its activation of VC inhibitors. There are positive studies; unfortunately, recent trials failed to prove its efficacy in preventing VC. Future research is needed and should aim to transform food into a medical intervention to eliminate VC danger in CKD.

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Section: Bioactive and Senolytic Food And Vascular Calcification In Ckdmentioning

confidence: 99%

Food to Prevent Vascular Calcification in Chronic Kidney Disease

Moldovan,

Rusu,

Potra

et al. 2024

Nutrients

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“…It plays a vital role in maintaining physical well-being [ 3 ], particularly in terms of its antioxidant [ 4 ], anticancer [ 5 ], cardiovascular disease prevention [ 6 ], immune improvement [ 7 ], and other good auxiliary effects. The recommended daily intake of Se for humans is 55 µg (MCGs) [ 8 ]. As a trace element, Se is crucial for numerous biological activities, such as thyroid hormone metabolism, antioxidant defense, immune system strengthening, and prevention of certain types of cancer [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

High Concentrations of Se Inhibited the Growth of Rice Seedlings

Liu,

Ma,

et al. 2024

Plants

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Selenium (Se) is crucial for both plants and humans, with plants acting as the main source for human Se intake. In plants, moderate Se enhances growth and increases stress resistance, whereas excessive Se leads to toxicity. The physiological mechanisms by which Se influences rice seedlings’ growth are poorly understood and require additional research. In order to study the effects of selenium stress on rice seedlings, plant phenotype analysis, root scanning, metal ion content determination, physiological response index determination, hormone level determination, quantitative PCR (qPCR), and other methods were used. Our findings indicated that sodium selenite had dual effects on rice seedling growth under hydroponic conditions. At low concentrations, Se treatment promotes rice seedling growth by enhancing biomass, root length, and antioxidant capacity. Conversely, high concentrations of sodium selenite impair and damage rice, as evidenced by leaf yellowing, reduced chlorophyll content, decreased biomass, and stunted growth. Elevated Se levels also significantly affect antioxidase activities and the levels of proline, malondialdehyde, metal ions, and various phytohormones and selenium metabolism, ion transport, and antioxidant genes in rice. The adverse effects of high Se concentrations may directly disrupt protein synthesis or indirectly induce oxidative stress by altering the absorption and synthesis of other compounds. This study aims to elucidate the physiological responses of rice to Se toxicity stress and lay the groundwork for the development of Se-enriched rice varieties.

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Association between dietary selenium intake and severe abdominal aortic calcification in the United States: a cross-sectional study

Abstract: Abdominal aortic calcification (AAC) is an important predictor of cardiovascular disease. The purpose of the current study was to detect the association between dietary selenium intake and severe AAC....

Cited by 2 publications

References 36 publications

Food to Prevent Vascular Calcification in Chronic Kidney Disease

Food to Prevent Vascular Calcification in Chronic Kidney Disease

High Concentrations of Se Inhibited the Growth of Rice Seedlings

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