Association between Dietary Glycaemic Index and Glycaemic Load and Adiposity Indices in Polycystic Ovary Syndrome

Melekoğlu, Ebru; Göksülük, Dinçer; Yıldız, Emine

doi:10.1080/07315724.2019.1705200

Cited by 8 publications

(6 citation statements)

References 43 publications

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“…This finding may be connected to the disorder. Furthermore, some previous studies have found that women with PCOS consume more calories than women without the illness, while other studies have not found any significant variations in dietary consumption or physical activity levels between PCOS-Ps and control groups [1,30,31]. On the other hand, we observed that PCOS-Ps consumed significantly less dietary fiber.…”

Section: Discussioncontrasting

confidence: 75%

A Comparative Study of Food Intake and Adipose Tissue Distribution in Saudi Women with Polycystic Ovarian Syndrome

Hurayb,

Alshammari,

Al-Khalifa

et al. 2024

Healthcare

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Polycystic ovary syndrome (PCOS) is a frequent disorder that affects reproductive-aged women and has reproductive, metabolic, and psychosocial effects. This research was intended to investigate the comparison between food intake and adipose tissue distribution in Saudi women suffering from PCOS and a control group. To determine the sociodemographic variables, a case–control study was performed with patients from King Fahad Medical City’s Reproductive Endocrine and Infertility Medicine Department (REIMD). The case–control study comprised 42 PCOS patients (PCOS-Ps) and 63 as a control group, all aged 20–45 years. Three-day records were collected from participants to estimate the nutrient intake of cases and controls. A body composition analyzer was used to measure body mass index (BMI), body fat (BF), and visceral fat (VF). Biochemical measurements were taken to determine the lipid profile, total testosterone, and serum vitamin D-25-OH. The women’s frequency distribution based on sociodemographic characteristics revealed significant differences within and between the groups. The variations in dietary intake between the PCOS-P and control groups were primarily in terms of total calories, carbohydrates, niacin, and folate, all of which were significantly higher in the PCOS-P group. Dietary fiber, unsaturated fat, vitamin A, vitamin B12, calcium, phosphorus, and selenium, on the other hand, were significantly higher in the control group. A majority of both groups had significantly higher BMI (overweight or obese) and higher BF, but normal VF. According to the findings, testosterone levels in PCOS-Ps were significantly higher than in the control group, but vitamin D-25-OH and high-density-lipoprotein cholesterol (HDL-C) were significantly lower. Age, monthly income, cholesterol, low-density-lipoprotein cholesterol (LDL-C), and testosterone were the fundamental causes impacting women’s anthropometric indices. In conclusion, although both groups were overweight or obese, and differences in calorie and nutrient intake, HDL-C, testosterone, and vitamin D-25-OH levels were observed. The study advises such population groups to limit their consumption of foods high in calories.

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Section: Discussioncontrasting

confidence: 75%

A Comparative Study of Food Intake and Adipose Tissue Distribution in Saudi Women with Polycystic Ovarian Syndrome

Hurayb,

Alshammari,

Al-Khalifa

et al. 2024

Healthcare

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“…Sam (2007) showed that exposure to high androgen levels in post-menopausal women causes an increase in visceral adipose tissue. The weight gain occurring in PCOS has been ascribed to insulin and glucose metabolism (Melekoglu et al 2019;Zeng et al 2019). No increase in weight between the beginning and end of the experiment in the PCOS + AMI group in this study, suggesting that AMI may have a positive effect on weight gain in patients with PCOS.…”

Section: Discussionmentioning

confidence: 55%

An investigation of the potential effects of amitriptyline on polycystic ovary syndrome induced by estradiol valerate

Alkan

Kaplan

2023

Histochem Cell Biol

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Polycystic ovarian syndrome (PCOS) is frequently observed in adolescent women and usually progresses with depression. The aim of this study was to examine the effects of amitriptyline (AMI), a drug used in the treatment of depression, in individuals with PCOS. Forty 12-week-old female Wistar albino rats were randomly divided into ve groups; control, sham, PCOS, AMI, PCOS+AMI. In order to induce the syndrome in the PCOS groups, a single dose of 4mg/kg estradiol valerate was administered by intraperitoneal injection, 10mg/kg AMI was administered by intraperitoneal injection for 30days in the AMI groups. After 30days, all the animals were sacri ced and blood, ovary, brain tissues were collected, subjected to routine tissue processing. Stereological, histopathological analyses were performed on the ovarian sections, while LH, FSH, CAT, and SOD levels were investigated in blood samples. The volume of the corpus luteum and preantral follicles increased in the PCOS group, while a decrease was determined in the number of antral follicles using stereological methods. Biochemical analysis revealed that FSH levels increased and CAT enzyme levels decreased in the PCOS group. Signi cant morphological changes were observed in ovaries from the PCOS group. The volume of the corpus luteum in the PCOS+AMI group decreased compared to the PCOS group. Serum FSH levels decreased in the PCOS+AMI group, while CAT enzyme levels increased compared to the PCOS group. Degenerative areas were also seen in the PCOS+AMI group ovaries. AMI administration was unable to su ciently ameliorate the morphological and biochemical changes caused in the ovarian tissues by PCOS.

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“…Regarding the GI and GL indexes, healthy but also PCOS women consuming high-GI or high-GL diets were found to have a higher BMI and waist circumference [38,39]. A significant inverse association between dietary GL and waist-to-hip ratio in women with PCOS was also reported [86].…”

Section: Effects Of Dietary Gi and Gl Indexes On Weight Statusmentioning

confidence: 85%

Glycemic Index and Glycemic Load Estimates in the Dietary Approach of Polycystic Ovary Syndrome

Manta,

Paschou,

Isari

et al. 2023

Nutrients

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Polycystic ovary syndrome is a common endocrine disorder characterized by hormonal imbalances and various metabolic abnormalities linked to insulin resistance via a vicious cycle. Genetic and environmental factors underlie its pathogenesis and evolution. Nutrition, in terms of nutrient composition, dietary patterns, endocrine-disrupting chemicals, and food processing and preparation, has gained significant attention in the pathogenesis and the therapeutic approach of polycystic ovary syndrome. Carbohydrate intake seems to be a critical point in the diet assignment. Glycemic index and glycemic load constitute indexes of the impacts of dietary carbohydrates on postprandial glucose levels. Numerous studies have indicated that a high glycemic index and glycemic load diet may exacerbate insulin resistance, a key feature of the syndrome, and offer a risk for its development and its complications. Conversely, low-glycemic index and low-glycemic load diets seem to improve insulin sensitivity, regulate menstrual cycles, and mitigate the risk of comorbidities associated with polycystic ovary syndrome, such as obesity, alterations in body composition, type 2 diabetes, cardiovascular disease, and quality of life. This comprehensive review aims to explore the relevance of nutrition and more specifically, the association of glycemic index and glycemic load with the various aspects of polycystic ovary syndrome, as well as to assess the potential benefits of manipulating those indexes in the dietary approach for the syndrome.

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Association between Dietary Glycaemic Index and Glycaemic Load and Adiposity Indices in Polycystic Ovary Syndrome

Cited by 8 publications

References 43 publications

A Comparative Study of Food Intake and Adipose Tissue Distribution in Saudi Women with Polycystic Ovarian Syndrome

A Comparative Study of Food Intake and Adipose Tissue Distribution in Saudi Women with Polycystic Ovarian Syndrome

An investigation of the potential effects of amitriptyline on polycystic ovary syndrome induced by estradiol valerate

Glycemic Index and Glycemic Load Estimates in the Dietary Approach of Polycystic Ovary Syndrome

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