Association between diet quality and BMI with side effects of Pfizer-BioNTech COVID-19 vaccine and SARS-CoV-2 immunoglobulin G titers

Abstract

Purpose The nutritional and anthropometric status can be essential in determining their immune response to vaccines. The purpose of this paper was to investigate the association between diet quality and anthropometric indices with the side effects of the Pfizer-BioNTech COVID-19 vaccine and the SARS-CoV-2 immunoglobulin G titer among Kurdish adults. Design/methodology/approach This cross-sectional survey-based study was conducted between December 2021 and February 2022. This paper included data on 115 adults, 20–89 years old, from the Kurdistan region. Dietary information was collected using a short food frequency questionnaire, and diet quality was assessed using a plant-based healthy diet score. A blood test was performed to measure the SARS-CoV-2 immunoglobin G (IgG) titer after the vaccination's first and second doses. Findings Overweight and obese subjects reported more local pain, myalgia, headache, local bruising and local reactions after receiving the first dose of the vaccine (p = 0.04). People on a less healthy diet reported more local pain, myalgia and headache (p = 0.04) and more local bruising and reactions (p = 0.01) after receiving the second dose of the vaccine. On the other hand, the authors observed that those with healthy dietary habits had more IgG titer after the first and second doses of vaccination than those with less healthy dietary habits (p = 0.001). Originality/value The results showed that participants with a healthy diet and normal weight status had fewer side effects of the Pfizer-BioNTech COVID-19 vaccine than obese people and those with a less healthy diet.

The Study on Side Effects Caused by Pfizer/BioNTech COVID-19 Vaccine: Focus on IgG Antibodies, and Serological Biomarkers

“…In addition, contrary to our ndings, the male gender had lower IgG levels after vaccination [38]. It has been reported that people with a healthy diet habits showed greater IgG titers following the rst and second doses of the COVID-19 vaccine than those with less healthy eating habits [39].…”

A study on the side effects caused by the Pfizer/BioNTech COVID-19 vaccine: Focus on IgG antibodies and serological biomarkers

“…In addition, contrary to our findings, the male gender had lower IgG levels after vaccination [ 37 ]. It has been reported that people with healthy dietary habits showed greater IgG titers following the first and second doses of the COVID-19 vaccine than those with less healthy eating habits [ 38 ].…”

Clinical outcomes and phylogenetic analysis in reflection with three predominant clades of SARS‐CoV‐2 variants

“…Monitoring SARS‐CoV‐2 mutations and their respective frequencies is an essential backup for the discovery of drug of choice and vaccines industry 27 . Presumably, world well‐known organizations somehow can gain benefit from the output of this kind of investigation.…”

“…26 Monitoring SARS-CoV-2 mutations and their respective frequencies is an essential backup for the discovery of drug of choice and vaccines industry. 27 Presumably, world well-known organizations somehow can gain benefit from the output of this kind of investigation. Consequently, prestigious and stepwise cooperation and collaboration with regard to genomics data of the epidemic is unavoidable to tackle this issue, which is facing humanity.…”