Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway

Zerah, Lorène; Cohen-Bittan, Judith; Raux, Mathieu; Mézière, Anthony; Tourette, Cendrine; Néri, Christian; Verny, Marc; Riou, Bruno; Khiami, F.; Boddaert, Jacques

doi:10.3233/jad-160655

Cited by 18 publications

(13 citation statements)

References 39 publications

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“…Third, the prevalence of dementia may have been underestimated, as diagnosis was based on clinical history. Yet, our results are consistent with previous data reported in this setting [45,46]. Fourth, cystatin C is known to be an inflammatory marker [47].…”

Section: Discussionsupporting

confidence: 93%

Renal function and delirium in older fracture patients: different information from different formulas?

Mossello

Rivasi

Tortù

et al. 2020

European Journal of Internal Medicine

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Section: Discussionsupporting

confidence: 93%

Renal function and delirium in older fracture patients: different information from different formulas?

Mossello

Rivasi

Tortù

et al. 2020

European Journal of Internal Medicine

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“…Nevertheless, all participants were informed of (and given the option to refuse) inclusion in the database, which was declared to the French national data privacy authority (Commission Nationale de l'Informatique et des Libertés, Paris, France). Some participants had been included in previous studies . The UPOG care pathway methodology has been described elsewhere …”

Section: Methodsmentioning

confidence: 99%

“…Some participants had been included in previous studies . The UPOG care pathway methodology has been described elsewhere …”

Section: Methodsmentioning

confidence: 99%

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Retrospective Evaluation of a Restrictive Transfusion Strategy in Older Adults with Hip Fracture

Zerah

Dourthe

Cohen-Bittan

et al. 2018

J American Geriatrics Society

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“…All seven studies were good quality studies based on the Newcastle Ottawa Scale. Zerah et al showed that POD was more frequent in patients with dementia with a demonstrated odds ratio of 3.12 (95% CI 1.97-4.96, P = 0.05) higher than patients without dementia, when controlled for potential confounders [10]. Culley et al found that 24% of patients screened positive for probable cognitive impairment using the Mini-Cog© test score cutoff of less than or equal to 2 [11].…”

Section: Association Of Cognitive Impairment With In-hospital Outcomesmentioning

confidence: 99%

Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: A systematic review

Viramontes

Erfe

et al. 2019

Journal of Clinical Anesthesia

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Total hip arthroplasty (THA) is a common surgical procedure in the elderly. Varying degrees of cognitive impairment (CI) are frequently seen in this patient population. To date, there has been no systematic review of the literature specifically examining the impact of CI on outcomes after elective THA. The aim of this systematic review was to identify studies that compare the postoperative outcomes of patients with and without CI after undergoing elective primary THA. Design: We conducted a systematic review of prospective and retrospective studies. A systematic literature review was conducted by searching MEDLINE, PubMed, and Embase from between January 1, 1997 and January 1, 2018. A total of 234 articles were reviewed and 22 studies were selected. Setting: Operating room and short-term and long-term postoperative recovery up to 2 years. Patients: Patients with CI who underwent an elective primary THA that required general anesthesia with a comparator group of patients who did not have dementia. Interventions: Patients who underwent elective primary total hip arthroplasty. Measurements: Outcomes included post-operative delirium (POD), mortality and other complications, discharge disposition, length of stay (LOS), mortality, short-term (30 days) and long-term (1 month-2 years) complications. Main results: 22 studies with 5,705,302 participants were included in the systematic review. Sample sizes varied greatly, ranging from 14 to 2,924,995 participants. There was an association between patients with CI and an increase in POD, in-hospital mortality, complications during hospitalization, non-routine disposition, LOS, mortality between 1 month to 2 years, and worse postoperative functional status. Conclusions: We demonstrate that there are strong associations between patients with pre-existing CI undergoing THA and increased POD, hospital mortality, hospital complications, and hospital LOS. We report good quality evidence linking complications after THA to preexisting CI. Screening for CI can improve care and better predict the risk of developing postoperative complications such as delirium. Further investigations can address perioperative factors that can help reduce complications and show the utility of more widespread assessment of preoperative cognitive impairment.

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Association between Cognitive Status before Surgery and Outcomes in Elderly Patients with Hip Fracture in a Dedicated Orthogeriatric Care Pathway

Cited by 18 publications

References 39 publications

Renal function and delirium in older fracture patients: different information from different formulas?

Renal function and delirium in older fracture patients: different information from different formulas?

Retrospective Evaluation of a Restrictive Transfusion Strategy in Older Adults with Hip Fracture

Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: A systematic review

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