Association between Cockroach-specific Immunoglobulin E and periodontitis in Korean male adults Based on Korean National Health and Nutrition Examination Survey

Abstract

Periodontitis is an inflammatory disease affecting the tooth supporting tissues (periodontium) and associated with chronic diseases such as cardiovascular disease and insulin resistance. However, there has been no nation-wide population based epidemiologic study regarding any association between periodontitis and serum IgE. Among the 8,958 participants in the 2010 Korean National Health and Nutrition Examination Survey (KNHANES V-1), 1,731 adults aged 19 to 64 who had measured serum IgE were included in the analysis. Dentists examined the periodontal status of the participants. Multiple logistic regression analyses were used to evaluate the odds ratio of periodontitis in association with total IgE and specific IgE to cockroach and house dust mite. In males, total IgE showed a positive correlation with the presence of periodontitis. The participants in the highest tertile of cockroach specific IgE (T3, >31.6 kU/L) had a significantly increased risk of periodontitis (OR = 2.108; 95% CI, 1.233–3.606). In females, the inverse association occurred between total IgE and periodontitis (OR = 0.409; 95% CI, 0.200–0.839). The present study firstly demonstrated the association between periodontitis and serum IgE, using the Korean nationwide, population-based, cross-sectional health examination and survey. This study suggested a positive correlation between periodontitis and cockroach-specific IgE in Korean male adults.

Clinical implication of fasting glucose and systolic/diastolic blood pressure on the prevalence of periodontitis in non‑diabetic and non‑hypertensive adults using nationally representative data

“…This study has great strength because the conclusion was derived from nationally representative data (29). The design of this study is based on a stratified, multistage, probability-cluster survey of the population of institutionalized civilians (30). Oral health was evaluated using periodontal index from index teeth using probing depth (31).…”

Plasma elaidic acid level is associated with periodontal health in American adults: A cross-sectional study

“…In order to know whether the plasma EA concentration of the participants included in the study is related to the severity of periodontitis, we divided the statistical analysis into three main steps. To begin, the plasma EA concentrations were separated into three groups based on the tertile level, and the baseline data distribution of participants in this study in various plasma EA concentrations (tertile and overall) was provided ( 45 ). The differences between the three tertile groups are demonstrated using the chi-square test (categorical variables), One-Way ANOVA (normal distribution), or Kruskal-Wallis test (skewed distribution).…”

House dust mite and Cockroach specific Immunoglobulin E sensitization is associated with diabetes mellitus in the adult Korean population

“…The survey was performed by the Korean Ministry of Health and Welfare and had three components: a health interview survey, a health examination survey, and a nutrition survey. Notably, the 2010 KNHANES gathered information on serum total and allergen-specific IgE levels from 2,342 participants randomly chosen from every age and sex group in each district; thus, the data were representative of the general Korean population 11 , 12 . Of the 2,342 participants, we excluded those younger than 30 years (n = 765); those who had not fasted sufficiently prior to blood sampling (<8 h) (n = 33); and those for whom data on at least one variable were missing (n = 16).…”