“…Aldajani and colleagues conducted a meta-analysis assessing the association between reflux diseases (laryngopharyngeal reflux [LPR] and gastroesophageal reflux [GERD]) and CRS. 6 The study revealed a significant association between GERD, LPR, and CRS compared to control groups, along with higher pH values and pepsin detection in CRS patients. Additionally, studies evaluating proton inhibitor therapy in CRS patients consistently reported positive outcomes.…”