Association between C-reactive protein, neutrophil to lymphocyte ratio and the burden of apical periodontitis: a case-control study

Şirin, Dursun Ali; Özçelik, Furkan; Uzun, Canan; Erşahan, Şeyda; Yeşilbaş, Soner

doi:10.1080/00016357.2018.1522447

Cited by 22 publications

(40 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6 Additionally, Sirin et al reported that the level of CRP increases with the severity of AP. 7 Many similarities in the pathogenesis of both AS and AP might suggest a relationship between them. However, there have been no studies evaluating the possible association between AS and AP.…”

Section: Introductionmentioning

confidence: 99%

Association of ankylosing spondylitis with radiographically and clinically diagnosed apical periodontitis: A cross-sectional study

2020

View full text Add to dashboard Cite

Background. There are no studies evaluating the possible association between ankylosing spondylitis (AS) and apical periodontitis (AP). Objectives. The aim of the present cross-sectional study was to investigate the possible association between AS and AP. Material and methods. Fifty patients diagnosed with AS, receiving treatment at the Rheumatology Clinic in Erzurum, Turkey, were included in the experimental group. Another 50 age-and gender-matched individuals without any history of systemic disease were included in the study as the control group. All patients were examined radiographically and clinically to diagnose the presence of AP. The following data was recorded for all patients: the smoking habit, the number of teeth present, the number of teeth with AP, the number of root canal-treated (RCT) teeth, and the number of RCT teeth with AP. Results. There were 1,283 teeth in the AS group and 1,305 in the control group. There was a significant association between teeth with AP and AS, as the prevalence of teeth with AP was significantly lower in the control group (1.3%) than in the AS group (2.9%) (OR (odds ratio) = 2.250; p = 0.005). There was no statistically significant difference between the groups in terms of the number of RCT teeth and RCT teeth with AP (p > 0.05). Conclusions. Ankylosing spondylitis is significantly associated with an increased prevalence of AP. It can be concluded that patients with AS can be more prone to develop AP. However, AS does not reduce the success rate of endodontic treatment, because there was no significant difference between the AS and control groups in terms of RCT teeth with AP.

show abstract

Section: Introductionmentioning

confidence: 99%

Association of ankylosing spondylitis with radiographically and clinically diagnosed apical periodontitis: A cross-sectional study

2020

View full text Add to dashboard Cite

show abstract

“…In recent years, RBL measurement on panoramic radiographs has been performed using methods that automatically detect bone loss such as CAD based on deep learning and the convolution neural network (CNN) [ 16 , 17 , 28 ]. We successfully used the APGS classification, which we created based on the PAI, in the evaluation of AP in our previous studies [ 7 , 8 ]. This classification was also compatible with the markers associated with inflammatory process (IL-6, hsCRP and PAPP-A).…”

Section: Discussionmentioning

confidence: 99%

“…The PAI scoring system numbers the teeth for AP from 1 to 5 according to radiolucency of the periapex on radiographs. The Apical Periodontitis Grading Scale (APGS), which was developed by Sirin et al based on PAI, is a new scale used to that classifies the AP according to the number of affected teeth and the severity of AP and has been used in several studies [ 7 , 8 ]. According to the APGS, patients with PAI score 1 and 2 are categorized as AP Grade 0, those with only one tooth included AP with a PAI score of 3 or 4 are considered AP Grade 1, those with more than one tooth included AP with a PAI score of 3 or 4 are classified as AP Grade 2, and those with at least one tooth included AP scored as a PAI 5 are described as AP Grade 3.…”

Section: Introductionmentioning

confidence: 99%

The relationship between COVID-19 and the dental damage stage determined by radiological examination

Şirin

Özçeli̇k

2021

Oral Radiol

View full text Add to dashboard Cite

“…Recent studies have also revealed that AP could trigger a systemic immune response and affect the general health of patients. Although AP is accepted as an inflammatory disease, the use of inflammatory markers is restricted in its assessment (Sirin, Ozcelik, Uzun, Ersahan, & Yesilbas, 2019). Oral diseases causing increased CRP levels are also associated with the increased risk of CVD (Cotti & Mercuro, 2005).…”

Section: Introductionmentioning

confidence: 99%

“…Oral diseases causing increased CRP levels are also associated with the increased risk of CVD (Cotti & Mercuro, 2005). CRP levels can be used to evaluate systemic inflammation in patients with AP (Sirin et al., 2019).…”

Section: Introductionmentioning

confidence: 99%

The effect of treated apical periodontitis before heart valve surgery on C‐reactive protein levels

2020

View full text Add to dashboard Cite

Objective Dental infections produce significant increases in systemic inflammatory responses manifested by cytokines and acute‐phase reactants. This study evaluated the postoperative C‐reactive protein (CRP) levels according to patients having teeth treated or not treated for apical periodontitis (AP) before heart valve surgery. Materials and Methods Preoperative, postoperative third‐ and fifth‐day CRP levels, and the previous dental data of 91 patients were investigated. Whether the patients had been treated for AP and whether they used antibiotic prophylaxis for this treatment were determined by examining the previous data. The analysis of covariance (ANCOVA) was used for statistical analysis. Results There were no statistically significant differences in the preoperative CRP levels and the third‐day CRP levels between all patients treated and those not treated for AP (p > .05). The mean fifth‐day CRP levels of the patients with teeth treated for AP were significantly lower than those of the patients with teeth not treated for AP (p < .05). Antibiotic prophylaxis had a significant effect on the fifth‐day CRP levels. Conclusion The decrease in CRP levels after AP treatment may contribute to alleviating heart valve disease and maintaining cardiac health.

show abstract

Association between C-reactive protein, neutrophil to lymphocyte ratio and the burden of apical periodontitis: a case-control study

Cited by 22 publications

References 41 publications

Association of ankylosing spondylitis with radiographically and clinically diagnosed apical periodontitis: A cross-sectional study

Association of ankylosing spondylitis with radiographically and clinically diagnosed apical periodontitis: A cross-sectional study

The relationship between COVID-19 and the dental damage stage determined by radiological examination

The effect of treated apical periodontitis before heart valve surgery on C‐reactive protein levels

Contact Info

Product

Resources

About