Association Between Baseline Angle Width and Induced Angle Opening Following Prophylactic Laser Peripheral Iridotomy

Lee, Roland; Kasuga, Toshimitsu; Cui, Qi N.; Huang, Guofu; He, Mingguang; Lin, Shan

doi:10.1167/iovs.13-11597

Cited by 33 publications

(27 citation statements)

References 38 publications

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“…See et al [29] found an increase of ACA width but no change of ACD in 17 eyes of 17 patients with suspected primary angle closure, primary angle closure, or primary angle closure glaucoma using AS-OCT. Using the AS-OCT in a group of 84 eyes of 52 angle closure suspects, it could be found that prophylactic LPI causes ACA to increase significantly and that narrower angles at baseline before LPI are associated with a more pronounced increase of ACA than wider angles [30]. Lee et al [31] could show that anterior chamber area and ACA increase after LPI in 32 eyes of 32 primary angle closure suspects but decreases again thereafter so that 18 months after LPI, a group of ACA indices are not statistically different from their pre-LPI values anymore.…”

Section: Discussionmentioning

confidence: 99%

Changes of anterior chamber architecture induced by laser peripheral iridotomy in acute angle closure crisis

2014

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In acute angle closure crisis (AAC), a laser peripheral iridotomy (LPI) is performed to balance the pressure gradient between anterior and posterior chamber. The hereby induced changes in anterior chamber architecture were analyzed using Scheimpflug photography (SP). SP was performed in eyes with AAC and in fellow eyes (FE) before and after LPI. Intraocular pressure (IOP), anterior chamber volume (ACV), anterior chamber depth (ACD), anterior chamber angle width (ACA), and central corneal thickness (CCT) were analyzed. The group consisted of 18 patients (14♀, 4♂; 69 ± 11 years) with unilateral AAC. Mean IOP in AAC eyes decreased from 49.3 ± 2.8 mmHg at presentation to 13.7 ± 1.6 mmHg after LPI (p = 0.001). Mean ACV increased from 48.2 ± 3.6 to 60.6 ± 2.4 mm(3) in AAC eyes (p < 0.001) and from 60.4 ± 4.6 to 74.1 ± 3.7 mm(3) in the FE (p < 0.001). Mean ACD increased from 1.27 ± 0.08 to 1.44 ± 0.06 mm (p = 0.01) in AAC eyes and decreased in FE from 1.72 ± 0.08 to 1.59 ± 0.04 mm (p = 0.5). Mean ACA increased from 16.8 ± 1.6 to 20.5 ± 1.5° in AAC eyes (p = 0.01) and from 18.5 ± 1.4 to 22.6 ± 1.5° in the FE (p = 0.01). Mean CCT did not change significantly in both groups after LPI (AAC p = 0.09; FE p = 0.9) but a statistically significant difference between the two groups was detectable before LPI (p = 0.04) which disappeared thereafter (p = 0.14). Using Scheimpflug photography, a significant difference of ACV, ACD, and ACA can be detected after LPI in eyes suffering from acute angle closure crisis which demonstrates the effectiveness of LPI.

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Section: Discussionmentioning

confidence: 99%

Changes of anterior chamber architecture induced by laser peripheral iridotomy in acute angle closure crisis

2014

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“…This procedure has previously been used in our other studies. 11–14 The following parameters were derived from the Zhongshan Angle Assessment Program: trabecular-iris space area at 750 μm from the scleral spur, angle opening distance at 750 μm from the scleral spur, anterior chamber area, anterior chamber volume, anterior chamber width, lens vault, iris thickness measured at 750 μm from the scleral spur, iris area, and pupil diameter.…”

Section: Methodsmentioning

confidence: 99%

Association of Ocular Conditions With Narrow Angles in Different Ethnicities

Lee

Chon

Lin

et al. 2015

American Journal of Ophthalmology

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Purpose To quantify the predictive strength of anterior chamber area (ACA), anterior chamber volume (ACV), anterior chamber width (ACW), lens vault (LV), iris thickness (IT), and iris area (IArea) for two angle width parameters, trabecular-iris space area (TISA750) and angle opening distance (AOD750) at 750 μm from the scleral spur, in different ethnicities. Design Prospective, cross-sectional study. Methods Anterior segment optical coherence tomography images for 166 white, 90 African, 75 Hispanic, and 132 Chinese subjects were analyzed. First, ACA, ACV, ACW, LV, IT, and IArea were compared among ethnic groups. Second, associations of TISA750 and AOD750 with ACA, ACV, ACW, LV, IT and IArea were investigated within each ethnic group using multivariable linear regression models, standardized regression coefficients (β), and coefficients of determination (R2). Results Significant ethnic differences were observed in ACA, ACV, ACW, LV, IT, and IArea (all P<0.05). ACA, ACV, and LV were significant predictors of TISA750 and AOD750 in all ethnic groups (all P<0.001). ACW and IT were significant predictors of AOD750 in whites and Africans (all P<0.05). ACW and IT were significant predictors of TISA750 in whites (all P<0.05). IArea was a significant predictor of AOD750 in Chinese (P<0.05). ACA, ACV, and LV had the highest predictive strength for both TISA750 and AOD750 in all ethnic groups based on β and R2. Conclusions Despite ethnic differences in ACA, ACV, ACW, LV, IT, and IArea, the same three anterior segment parameters (ACA, ACV, and LV) were the strongest predictors of angle width (TISA750 and AOD750) in all four ethnic groups.

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“…The above-listed ASOCT parameters were defined previously in our other studies 16 17. AOD500 was defined as the length of the line extending from the anterior iris to the corneal endothelium, perpendicular to the line drawn along the trabecular meshwork at 500 μm anterior to the scleral spur.…”

Section: Methodsmentioning

confidence: 99%

Association between light-to-dark changes in angle width and iris parameters in light, dark and changes from light-to-dark conditions

et al. 2016

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Association Between Baseline Angle Width and Induced Angle Opening Following Prophylactic Laser Peripheral Iridotomy

Cited by 33 publications

References 38 publications

Changes of anterior chamber architecture induced by laser peripheral iridotomy in acute angle closure crisis

Changes of anterior chamber architecture induced by laser peripheral iridotomy in acute angle closure crisis

Association of Ocular Conditions With Narrow Angles in Different Ethnicities

Association between light-to-dark changes in angle width and iris parameters in light, dark and changes from light-to-dark conditions

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