Association between atopic dermatitis and thyroid disease among U.S. adults in the 2001-2006 National Health and Nutrition Examination Survey

Smith, Brandon; Collier, M. R.; Devjani, Shivali; Han, George; Wu, Jashin J.

doi:10.1016/j.jaad.2022.10.017

Cited by 6 publications

(1 citation statement)

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“…between AD and thyroid dysfunction in adults is limited, a study by Smith et al reported a significant association between the two, particularly in younger males, after accounting for potential confounders. 70 This connection may be due to shared immune dysregulation and cytokine pathways, and is further supported by overlapping genetic susceptibility loci. 71…”

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confidence: 99%

Association Between Atopic Dermatitis and Aging: Clinical Observations and Underlying Mechanisms

Chen,

Shen,

Cai

et al. 2024

JIR

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As one of the most prevalent chronic inflammatory skin diseases, atopic dermatitis (AD) increasingly affects the aging population. Amid the ongoing global aging trend, it's essential to recognize the intricate relationship between AD and aging. This paper reviews existing knowledge, summarizing clinical observations of associations between AD and aging-related diseases in various systems, including endocrine, cardiovascular, and neurological. Additionally, it discusses major theories explaining the correlation, encompassing skin-mucosal barriers, systemic inflammation and stress, genes, signal transduction, and environmental and behavioral factors. The association between AD and aging holds significant importance, both in population and basic perspectives. While further research is warranted, this paper aims to inspire deeper exploration of inflammation/allergy-aging dynamics and the timely management of elderly patients with AD.

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confidence: 99%