Association between arthritis and depression risk: a prospective study and meta-analysis

Xue, Qingping; Pan, An; Gong, Jessica; Wen, Ying; Peng, Xiaoyan; Ju, Ke; Pan, Xiong‐Fei

doi:10.1016/j.jad.2020.04.038

Cited by 13 publications

(15 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Second, measurement errors may perhaps not be entirely excluded and would be another source of bias. Although CESD-10 used to evaluate depression has been validated and shown fair reliability among Chinese community-dwelling adults [ 29 ], misclassification of depressive symptoms would also exist due to the unavailability of a clinical diagnostic tool for depression in CHARLS. Knee pain was measured via single self-report through binary options, i.e., yes or no.…”

Section: Discussionmentioning

confidence: 99%

“…In the questionnaires, knee pain was assessed by asking whether the participants had experienced knee pain in the past month. Following previous studies [ 29 , 30 ], participants were classified into two subgroups: persistent and incident knee pain. Participants with persistent knee pain refer to those reporting knee pain during two or more consecutive follow-up waves.…”

Section: Methodsmentioning

confidence: 99%

“…Ten items’ summation score may range from 0 to 30, with higher values indicating more severe depressive symptoms. A total CESD-10 score of 10 or greater was commonly used to indicate clinically significant depression for Chinese adults [ 29 ].…”

Section: Methodsmentioning

confidence: 99%

“…Consistent with previous studies [ 17 , 29 , 33 ], the following covariables were included. The interviewer-administered questionnaire obtained all the covariates at the baseline survey.…”

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Association of depressive symptoms and risk of knee pain: the moderating effect of sex

Liu

et al. 2021

BMC Musculoskelet Disord

Self Cite

View full text Add to dashboard Cite

Background Depression has been shown in some studies to be associated with knee pain. Females were widely recognized as more vulnerable to depression and knee pain than males. However, the role of sex in this correlation was under-researched. This study aimed to investigate the association between depressive symptoms and subsequent knee pain, as well as whether and how sex would moderate this association based on a four-wave (Wave 1 in 2010–2011, Wave 2 in 2013, Wave 3 in 2015, and Wave 4 in 2018) longitudinal study among middle-aged and elderly Chinese adults. Methods Seventeen thousand seven hundred eight participants were recruited and followed in the China Health and Retirement Longitudinal Study (CHARLS). Ten thousand four hundred fifty-one entered the final analysis based on the inclusion and exclusion criteria. Knee pain was assessed by self-report. Depressive symptoms were evaluated using the validated 10-item Center for Epidemiological Studies-Depression Scale (CESD-10). Cox proportional hazards models were used to calculate hazard ratios with 95% confidence intervals (CIs) after controlling potential confounders to examine the association between depressive symptoms and subsequent incident and persistent knee pain. Non-linear association of depressive symptoms score (CESD-10) and risk of knee pain was also investigated via applying 3-knotted restricted cubic spline regression. An interaction term of depressive symptoms status and sex was added to investigate the moderating effect of sex on the relationship between depressive symptoms status and the risk of knee pain. Results The median follow-up time was seven years for all the outcomes. Participants with depressive symptoms were 1.45 times (95% CI: 1.34–1.56) and 2.16 times (95% CI: 1.85–2.52) more likely to develop the incident and persistent knee pain after multivariable were adjusted, compared with those without depressive symptoms. There was a non-linear association between CESD-10 score and risk of knee pain. Compared with females, males had an enhanced correlation between depressive symptoms status and knee pain (multivariable-adjusted HR: 1.22, 95% CI: 1.05–1.42 and HR: 1.57, 95% CI: 1.14–2.17 for the incident and persistent knee pain, respectively). Conclusion Depressive symptoms are independently associated with an excess risk of knee pain, with a stronger correlation for males than females among middle-aged and elderly Chinese adults.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…Consistent with previous studies [ 17 , 29 , 33 ], the following covariables were included. The interviewer-administered questionnaire obtained all the covariates at the baseline survey.…”

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

Association of depressive symptoms and risk of knee pain: the moderating effect of sex

Liu

et al. 2021

BMC Musculoskelet Disord

Self Cite

View full text Add to dashboard Cite

show abstract

“…In our study, comparing the three groups (‘no disease’, ‘arthritis’, and ‘metabolic’), the arthritis group presents the lowest values for the variables grip strength and depressive symptoms. Other studies analysed the positive relationship between arthritis and depression [ 35 , 36 ], and arthritis and low grip strength [ 37 ]. Another important fact, that must be analysed in this study, is that the significant association between grip strength and depressive symptoms ceased to exist for individuals with arthritis diseases when the model was adjusted for the self-perceived health variable (in addition to gender, age, country, education, living place and BMI).…”

Section: Discussionmentioning

confidence: 99%

The Association of Grip Strength with Depressive Symptoms among Middle-Aged and Older Adults with Different Chronic Diseases

Marconcin

Peralta

Ferrari

et al. 2020

IJERPH

View full text Add to dashboard Cite

Low grip strength has been associated with an increase in depressive symptoms, independent of age group or gender, although the literature has not investigated this association among different chronic diseases. The present study aims to investigate the association of grip strength and depressive symptoms among middle-aged and older adults with different chronic diseases. A cross-section of data from the Survey of Health, Ageing, and Retirement in Europe wave 6 (collected in 2015) was analysed. Grip strength was measured by a handgrip dynamometer, and the European Depression Symptoms 12-item scale (EURO-D) was used to assess depressive symptoms. Multivariable logistic regression analysis was conducted. Those in the high strength tertile had 42% (95% confidence interval: 0.50, 0.71; p < 0.005) and 41% (95% confidence interval: 0.50, 0.70; p < 0.001) lower odds of depressive symptoms in the ‘no disease’ and in the ‘metabolic diseases’ groups of participants, respectively, compared with those in the lower strength tertile. No statistically significant relationship between grip strength and depression was observed in the ‘arthritis diseases’ group of participants. The association of grip strength with depressive symptoms must consider, besides gender and age group, the chronic conditions that an individual could have.

show abstract

High‐sensitivity C‐reactive protein and risk of type 2 diabetes: A nationwide cohort study and updated meta‐analysis

Yang

Tao

Peng

et al. 2021

Diabetes Metabolism Res

Self Cite

View full text Add to dashboard Cite

Objective To prospectively examine the association of high sensitivity C‐reactive protein (hs‐CRP) with incident type 2 diabetes mellitus (T2DM) among middle‐aged and elderly Chinese, and validate the association in an updated meta‐analysis of prospective studies. Methods We used data from the China Health and Retirement Longitudinal Study, started in 2011–2012 with follow ups in 2013–2014 and 2015–2016. Multivariable Cox proportional hazard regressions were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between hs‐CRP level and incident T2DM. An updated meta‐analysis was conducted to combine our estimates with those in previous prospective studies. Results Included in the analyses were 7985 participants (mean age: 59.38 years; men: 46.73%). Higher hs‐CRP was associated with increased risk of T2DM (multivariable‐adjusted HR, 1.30; 95% CI: 1.03, 1.64 for comparing extreme quartiles). The association was stronger in participants with body mass index (BMI) of 24.0 kg/m2 or higher than those with a BMI lower than 24.0 kg/m2 (p for interaction = 0.038). In a meta‐analysis of 28 cohorts, 2 case‐cohort, and 6 nested case‐control studies among 125,356 participants with 10,759 cases, the pooled relative risk for T2DM was 1.77 (95% CI: 1.60, 1.96) for the highest versus lowest level of hs‐CRP. Conclusions Hs‐CRP was associated with higher risk of T2DM in middle‐aged and elderly Chinese, and this association was confirmed by an updated meta‐analysis of prospective studies. Our findings highlight the role of elevated hs‐CRP in the development of T2DM.

show abstract

Association between arthritis and depression risk: a prospective study and meta-analysis

Cited by 13 publications

References 34 publications

Association of depressive symptoms and risk of knee pain: the moderating effect of sex

Association of depressive symptoms and risk of knee pain: the moderating effect of sex

The Association of Grip Strength with Depressive Symptoms among Middle-Aged and Older Adults with Different Chronic Diseases

High‐sensitivity C‐reactive protein and risk of type 2 diabetes: A nationwide cohort study and updated meta‐analysis

Contact Info

Product

Resources

About