Association Between Anti-Helicobacter pylori Antibody Seropositive and De Novo Gallstone Formation After Laparoscopic Sleeve Gastrectomy for Japanese Patients with Severe Obesity

Hashimoto, Kenkichi; Nagao, Yuhei; Nambara, Sho; Tsuda, Yasuo; Kudou, Kensuke; Kusumoto, Eiji; Sakaguchi, Yoshihisa; Kusumoto, Tetsuya; Izutsu, Koji

doi:10.1007/s11695-022-06253-z

Cited by 3 publications

(2 citation statements)

References 36 publications

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“…Nevertheless, H. pylori is associated with increased marginal ulceration rates in patients undergoing RYGB [45], and postoperative foregut symptoms are more common in H. pylori-infected patients [47,48]. Moreover, anti-H. pylori antibody seropositivity was found to be associated with de novo gallstone formation [49], a well-known complication of bariatric surgeries [50]. Regrettably, our study failed to find significant predictors of H. pylori infection.…”

Section: Discussioncontrasting

confidence: 59%

Endoscopic Assessment Prior to Bariatric Surgery in Saudi Arabia

Aljaroudi¹,

Makki²,

Almulaify³

et al. 2023

Cureus

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Background: There are marked local inconsistencies in the Arabian Peninsula about the role of preoperative esophagogastroduodenoscopy (EGD) in bariatric surgery. Thus, this study was conducted to determine the frequency of endoscopic and histological findings in the Saudi population presenting for pre-bariatric surgery evaluation.Material and Methods: This was a retrospective study that included all the patients who were evaluated by EGD at Dammam Medical Complex, Dammam, Saudi Arabia, between 2018 and 2021 as a part of their prebariatric-surgery evaluation.Results: A total of 684 patients were included. They consisted of 250 male and 434 female patients (36.5% and 63.5%, respectively). The mean ± standard deviation for the patients' age and body mass index (BMI) were 36.4±10.6 years and 44.6±5.1 kg/m 2 , respectively. Significant endoscopic or histopathological findings as defined by the presence of large (≥ 2 cm) hiatus hernia, esophagitis, gastroesophageal reflux disease (GERD), Barrett esophagus, gastric ulcer, duodenal ulcer, or intestinal metaplasia were found in 143 patients (20.9%); 364 patients (53.2%) were diagnosed to have Helicobacter pylori infection. Conclusion:The high number of significant endoscopic and histopathological findings in our study supports the routine use of preoperative EGD in all bariatric surgery patients. However, omitting EGD before Rouxen-Y gastric bypass (RYGB) in asymptomatic patients is still reasonable as the most frequently found significant findings, esophagitis, and hiatus hernia, are less likely to impact the operative plans in RYGB. Similarly, active surveillance and treatment of H. pylori infections in obese patients are important but it is not clear whether H. pylori eradication should be done before bariatric surgery.

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Section: Discussioncontrasting

confidence: 59%

Endoscopic Assessment Prior to Bariatric Surgery in Saudi Arabia

Aljaroudi¹,

Makki²,

Almulaify³

et al. 2023

Cureus

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“…Goday et al 11 evaluated if HP eradication treatment could influence the evolution of weight loss and metabolic markers after bariatric surgery and found that HP-treated patients had higher weight loss and higher reduction of triglycerides and glucose levels. Moreover, the impact of HP has been evaluated on the incidence of gallstone formation after SG and found anti-HP antibody seropositive to be associated with cholelithiasis 14,29 . Its relation to gastroesophageal reflux disease (GERD) has also been explored, but despite no association with the incidence of de novo GERD, improvement of symptoms was higher in those with HP-confirmed eradication than in those without HP infection.…”

Section: Discussionmentioning

confidence: 99%

Impact of Helicobacter Pylori on Early Postoperative Complications After Sleeve Gastrectomy: A Systematic Review and Meta-Analysis

DANTAS,

JAYME,

FILARDI

et al. 2023

ABCD, arq. bras. cir. dig.

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The impact of Helicobacter pylori (HP) on postoperative outcomes after sleeve gastrectomy (SG) is still controversial. A systematic review and meta-analysis were performed to compare the incidence of early complications after SG between HP-positive and HP-negative patients. Eight retrospective comparative studies were included, comprising 4,877 individuals. The prevalence of HP infection in gastric resected specimens ranged from 7.77 to 43.20%. There were no statistically significant differences between groups for overall complications (OR 1.46; 95%CI 0.95–2.23; p=0.08), bleeding (OR 1.35; 95%CI 0.70–2.60; p=0.38), and leak (OR 1.74; 95%CI 0.80–3.81; p=0.17) rates. The need for routine screening and treatment of HP infection before SG remains ambiguous.

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