Association between anatomical variations of the posterior communicating artery and the presence of aneurysms

Hu, Teng; Wang, Dongdong

doi:10.1080/01616412.2016.1238662

Cited by 11 publications

(7 citation statements)

References 30 publications

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“…Hemodynamic stress is critical in the formation of aneurysms, leading to progressive degradation and inflammatory changes of arterial walls 13. Ultimately, anatomic variations in the PcoA may encourage the formation and rupture of PcoA aneurysms 11 14–16…”

Section: Discussionmentioning

confidence: 99%

Impact of fetal-type posterior cerebral artery on recanalization of posterior communicating artery aneurysms after coil embolization: matched-pair case–control study

Choi

Cho

Yoo

et al. 2020

J NeuroIntervent Surg

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BackgroundIt is well known that hemodynamic stress may impact the recanalization of coiled aneurysms. One of the most common sites for aneurysms to develop is the posterior communicating artery (PcoA), the variants of which are defined by diameter ratios (PcoA/P1 segment).ObjectiveThis study was undertaken to investigate the impact of a fetal-type posterior cerebral artery (PCA) on recanalization of PcoA aneurysms after coil embolization based on matched-pair (fetal vs non-fetal PCA) analysis.MethodsA total of 480 consecutive PcoA aneurysms (PCA: fetal, n=156; non-fetal, n=324) subjected to coil embolization between January 2007 and June 2017 were selected for study. All lesions were followed for ≥6 months via radiologic imaging, grouped by adjacent PCAs as fetal (PcoA/P1 >1) or non-fetal (PcoA/P1 ≤1) type. Paired subjects were matched (1:1) for several relevant variables.ResultsOf the 480 coiled aneurysms, 159 (33.1%) showed recanalization (minor, 76; major, 83) in the course of follow-up (mean 33.8±21.9 months), developing significantly more often in fetal (37.8%) than in non-fetal (26.9%; p=0.020) PCA types. Once matched, however, 6-month and cumulative recanalization rates did not differ significantly by group (p=0.531 and p=0.568, respectively). Complications (hemorrhage, p=0.97; thromboembolism, p=0.94) during endovascular coil embolization also showed similar rates in these groups.ConclusionsThe chances of recanalization after coil embolization seem to be greater in PcoA aneurysms than in intracranial aneurysms overall, thus calling for careful follow-up monitoring. Surprisingly, PcoA type appeared unrelated in this regard.

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Section: Discussionmentioning

confidence: 99%

Impact of fetal-type posterior cerebral artery on recanalization of posterior communicating artery aneurysms after coil embolization: matched-pair case–control study

Choi

Cho

Yoo

et al. 2020

J NeuroIntervent Surg

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“…The ICA and the caudal part of the anastomosed branch of the nerve artery form the PCA ( 4 ). In the stage of 40 mm (8 weeks), the PCA appears as an extension of the posterior communicating artery (PComA) ( 5 ). The vertebra-basilar system is then formed and contributes to the blood supply of the PCA through the P1 segment.…”

Section: Introductionmentioning

confidence: 99%

“…During development, the diameter of the PCA-P1 segment gradually increases, while that of the PComA gradually decreases. At the time of birth, the PCA-P1 segment diameter is greater than that of the PComA, which represents the most common type known as the adult PCA ( 5 ). Stagnation in the process of embryonic development results in the following two cases.…”

Section: Introductionmentioning

confidence: 99%

Is fetal‑type posterior cerebral artery a risk factor for intracranial aneurysm as analyzed by multislice CT angiography?

Wan

2017

Exp Ther Med

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Fetal-type posterior cerebral artery (FTP) is a common anatomic variation that is closely associated with intracranial aneurysm. In the present study, multislice computed tomography angiography (CTA) was performed to assess whether FTP is a risk factor for intracranial aneurysm. CTA data of 364 consecutive cases of patients who were suspected with cerebrovascular disease or intracranial aneurysm of intracranial artery from 2013 to 2016 were reviewed and the incidence rates of FTP, other variations of the circle of Willis, intracranial aneurysm and FTP with intracranial aneurysm were evaluated. The χ2 test was used to assess the influence of FTP and gender on the incidence rates of other variations of the circle of Willis, intracranial aneurysm and internal carotid artery-posterior communicating artery (ICA-PComA) aneurysm. Binary logistic regression analysis was performed to assess the associations of FTP and gender with intracranial aneurysm and ICA-PComA aneurysm. Compared with non-FTP patients, FTP cases exhibited significantly higher rates of other variations of the circle of Willis (χ2=80.173, P<0.001) and ICA-PComA aneurysm (χ2=4.437, P=0.035). Among patients with FTP and bilateral FTP, more female than male patients with intracranial aneurysm were identified. However, among all patients with intracranial aneurysm, no statistically significant differences in the prevalence of FTP (χ2=2.577, P=0.108) and bilateral FTP (χ2=2.199, P=0.159) between males and females were identified. Binary logistic regression analysis revealed that FTP and gender were risk factors for intracranial aneurysm and ICA-PComA aneurysm. A moderate association between FTP and ICA-PComA aneurysm (OR=2.762) were identified, although there was a weak association between FTP and intracranial aneurysm [odds ratio (OR)=1.365]. Furthermore, a strong association was identified between gender and intracranial aneurysm (OR=0.328), and a moderate association existed between gender and ICA-PComA aneurysm (OR=0.357). In conclusion, female gender is an independent risk factor for intracranial aneurysm, and FTP and female gender are independent risk factors for ICA-PComA aneurysm.

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“…Non-aneurysmal ICAs were more curved in women than men, which could explain the increased predisposition to aneurysm formation in women. Similarly, Hu et al ( 24 ) reported that the correlation between the angles at C7 and C6, the ICA, and the presence of symptomatic PcoA; with smaller angles being significantly associated with increased frequency of PcoA. Finally, Rosato et al ( 25 ) showed that ICA angulation at the PcoA origin is significantly higher in vessels harboring PcoA aneurysms when compared with non-aneurysmal ICAs.…”

Section: Discussionmentioning

confidence: 92%

“…Previous studies have investigated a possible correlation between adjacent vessels and the presence of aneurysms at the internal carotid artery ( 10 , 24 , 25 ). Adel et al ( 10 ) evaluated the mean and peak curvatures of the intracranial ICA and showed that the presence of sidewall aneurysms was highly correlated with curvature in all the genders.…”

Section: Discussionmentioning

confidence: 99%

Increased Carotid Siphon Tortuosity Is a Risk Factor for Paraclinoid Aneurysms

Liu

Wang

et al. 2022

Front. Neurol.

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BackgroundGeometrical factors associated with the surrounding vasculature can affect the risk of aneurysm formation. The aim of this study was to determine the association between carotid siphon curvature and the formation and development of paraclinoid aneurysms of the internal carotid artery.MethodsDigital subtraction angiography (DSA) data from 42 patients with paraclinoid aneurysms (31 with non-aneurysmal contralateral sides) and 42 age- and gender-matched healthy controls were analyzed, retrospectively. Morphological characteristics of the carotid siphon [the posterior angle (α), anterior angle (β), and Clinoid@Ophthalmic angle (γ)] were explored via three-dimensional rotational angiography (3D RA) multiplanar reconstruction. The association between carotid siphon morphology and the formation of paraclinoid aneurysms was assessed through univariate analysis. After this, logistic regression analysis was performed to identify independent risk factors for aneurysms.ResultsSignificantly smaller α, β, and γ angles were reported in the aneurysmal carotid siphon group when compared with the non-aneurysmal contralateral healthy controls. The β angle was best for discriminating between aneurysmal and non-aneurysmal carotid siphons, with an optimal threshold of 18.25°. By adjusting for hypertension, smoking habit, hyperlipidemia, and diabetes mellitus, logistic regression analysis demonstrated an independent association between the carotid siphons angles α [odds ratio (OR) 0.953; P < 0.05], β (OR 0.690; P < 0.001), and γ (OR 0.958; P < 0.01) with the risk of paraclinoid aneurysms.ConclusionsThe present findings provide evidence for the importance of morphological carotid siphon variations and the likelihood of paraclinoid aneurysms. These practical morphological parameters specific to paraclinoid aneurysms are easy to assess and may aid in risk assessment in these patients.

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Association between anatomical variations of the posterior communicating artery and the presence of aneurysms

Cited by 11 publications

References 30 publications

Impact of fetal-type posterior cerebral artery on recanalization of posterior communicating artery aneurysms after coil embolization: matched-pair case–control study

Impact of fetal-type posterior cerebral artery on recanalization of posterior communicating artery aneurysms after coil embolization: matched-pair case–control study

Is fetal‑type posterior cerebral artery a risk factor for intracranial aneurysm as analyzed by multislice CT angiography?

Increased Carotid Siphon Tortuosity Is a Risk Factor for Paraclinoid Aneurysms

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