Association between air pollution exposure and coronary heart disease hospitalization in a humid sub-tropical region of China: A time-series study

Abstract

ObjectiveEmerging evidence has highlighted the possible links of environmental pollution with several cardiovascular diseases (CVDs). The current study aimed to explore the impact of short-term air pollution exposure on CHD hospitalization in Hefei.MethodsData about the daily number of CHD admissions (from 2014 to 2021) were retrieved from the First Affiliated Hospital of Anhui Medical University. Air pollutants and meteorological data were obtained from the China Environmental Monitoring Station and the China Meteorological Data Service Center, respectively. The correlation between air pollution and CHD hospitalization was assessed using distributed lag non-linear model (DLNM) and Poisson generalized linear regression.ResultsIn the single-pollutant model, NO2, O3, and CO strongly correlated with CHD hospitalization rate. Specifically, exposure to NO2 (lag0, relative risk [RR]: 1.013, 95%CI: 1.002–1.024, per 10 μg/m3 increase) and CO (lag13, RR: 1.035, 95%CI: 1.001–1.071, per 1 μg/m3 increase) revealed a positive correlation with an increased rate of CHD hospitalization. Interestingly, O3 had a protective association with hospitalization of CHD (lag0, RR: 0.993, 95%CI: 0.988–0.999, per 10 μg/m3 increase). Similar results, to those of the single-pollutant model, were revealed following verification using two-pollutant models. Subgroup analyses indicated that young people, women, and people in hot seasons were more susceptible to NO2 exposure, while the elderly, women, and people in cold seasons were more susceptible to O3. Furthermore, the elderly were more susceptible to CO exposure.ConclusionOverall, exposure to NO2 and CO increases the rate of CHD hospitalization, but exposure to O3 shows a protective association with the rate of CHD hospitalization. Therefore, early preventive measures against air pollutants should be applied to protect vulnerable patients with CHD.

The Effect of Extreme Temperature and Air Pollutant on Cardiovascular Disease in Ondo-State Nigeria

“…In this study, Feng et al [18] examine the correlation between brief exposure to air pollution and the occurrence of hospitalisations due to coronary heart disease (CHD) in Hefei, China. Their examination of daily CHD admissions, in conjunction with air pollution and meteorological data, reveals noteworthy associations between CHD hospitalisation rates and pollutants such as NO2, O3, and CO.…”

“…Some research employs intricate models such as Bi-LSTM, but the modelling approaches differ, leading to incorrect outcomes. Enhancing the reliability and replicability of air pollution studies necessitates the establishment and verification of standardised models [6,18]. Another notable disparity exists in the translation of research findings into impactful legislation and communitylevel initiatives aimed at mitigating the health consequences of air pollution.…”

Associations between PM2.5 Components and Mortality of Ischemic Stroke, Chronic Obstructive Pulmonary Disease and Diabetes in Beijing, China

“…Increasing evidence has shown that major air pollutants, such as PM 2.5 , particulate matter less than 10 μm in aerodynamic diameter (PM 10 ), nitrogen dioxide (NO 2 ) and sulfur dioxide (SO 2 ), carbon monoxide (CO) and ozone (O 3 ), are closely associated with increased risk of morbidity and mortality [ 9 , 10 , 11 , 12 ]. Especially for PM 2.5 , there is growing and consistent evidence that it leads to a sustained increase in mortality from cardiovascular and respiratory diseases [ 13 , 14 ].…”