Association between AGTTGFB1ESR1, and VDR gene variants with idiopathic pulmonary fibrosis (IPF) and pulmonary sarcoidosis (PS) clinical features

Ulitina, Anna; Novikova, Lubov; Ilkovich, Julia; Baranova, Olga; Макарова, Т. С.; Volkova, Eugenia; Pchelina, Sofya; Ilkovich, Mikhail M.; Дубина, М. В.

doi:10.1183/1393003.congress-2017.oa2906

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Group 15: Diffuse Parenchymal Lung Disease1

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2018

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“…Targeted medicine in ILD demands better phenotyping and endotyping of patients, and therefore a better knowledge of different potential pathogenic mechanisms. Multiple genetic biomarkers, such as specific transforming growth factor-β, single-nucleotide polymorphisms and telomeres, have been associated with poor clinical outcomes in IPF [ 59 – 62 ], while certain microRNAs may be used to improve diagnostic accuracy and evaluation of treatment response. Non-primarily fibrotic pathogenic pathways, including the inflammasome, may also represent promising therapeutic targets [ 63 , 64 ].…”

Section: Group 15: Diffuse Parenchymal Lung Diseasementioning

confidence: 99%

European Respiratory Society International Congress 2017: highlights from the Clinical Assembly

Kahn

Mekov

Fregonese³

et al. 2018

ERJ Open Res

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This article contains highlights and a selection of the scientific advances from the European Respiratory Society's Clinical Assembly (Assembly 1 and its six respective groups) that were presented at the 2017 European Respiratory Society International Congress in Milan, Italy. The most relevant topics from each of the groups will be discussed, covering a wide range of areas including clinical problems, rehabilitation and chronic care, thoracic imaging, interventional pulmonology, diffuse and parenchymal lung diseases, and general practice and primary care. In this comprehensive review, the newest research and actual data as well as award-winning abstracts and highlight sessions will be discussed.

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Section: Group 15: Diffuse Parenchymal Lung Diseasementioning

confidence: 99%