Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer+

Campostrini, Franco; Remo, Andrea; Astati, Laura; Zorzi, Manuel; Capodaglio, Giulia; Buffoli, Alberto; Moretti, Gaia; Monica, B.; Zanella, Caterina; Verlato, Giuseppe

doi:10.1007/s00066-020-01590-3

Cited by 8 publications

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Indeed, adiponectin protects fibroblasts from radioinduced cell death, but not prostate cancer cells in mouse models. Campostrini et al (65) found that a substantial biopsy-proven gland and crypts loss in anterior rectal wall following irradiation could be considered strongly predictive of late proctitis. These authors recommended delivering a mean dose ≤48-52 Gy to the anterior rectal wall to minimize the depletion of both rectal mucosal gland and crypts.…”

Section: Increased Understanding Of Pathogenesis and Predictive Signatures Supporting Possible Therapeutic Implicationsmentioning

confidence: 99%

A Ten-year-long Update on Radiation Proctitis Among Prostate Cancer Patients Treated With Curative External Beam Radiotherapy

Ferini¹,

Pergolizzi

2021

In Vivo

View full text Add to dashboard Cite

This comprehensive synopsis summarizes the most relevant information obtained from a systematic analysis of studies of the last decade on radiation proctitis, one of the most feared radioinduced side effects among prostate cancer patients treated with curative external beam radiotherapy. The present review provides a useful support to radiation oncologists for limiting the onset or improving the treatment of radiation proctitis. This work shows that the past decade was a harbinger of significant new evidence in technological advances and technical tricks to avoid radiation proctitis, in addition to dosimetric perspectives and goals, understanding of pathogenesis, diagnostic work-up and treatment. We believe that a well-rounded knowledge of such an issue is fundamental for its appropriate management.

show abstract

Section: Increased Understanding Of Pathogenesis and Predictive Signatures Supporting Possible Therapeutic Implicationsmentioning

confidence: 99%

A Ten-year-long Update on Radiation Proctitis Among Prostate Cancer Patients Treated With Curative External Beam Radiotherapy

Ferini¹,

Pergolizzi

2021

In Vivo

View full text Add to dashboard Cite

show abstract

Proktitis (ohne chronisch-entzündliche Darmerkrankung)

Kronberger

2021

coloproctology

View full text Add to dashboard Cite

ZusammenfassungVermehrter Stuhldrang, Schleim‑/Blutabgänge sowie Läsionen an der Mukosa und ödematöse Veränderungen sind typische Beschwerden von Patienten mit Proktitis. Die Symptomatik und häufig auch die klinische Präsentation der Proktitiden sind nicht selten unspezifisch bzw. ähnlich und bedürfen aufgrund der drohenden Komplikationen mit Lebensqualitätseinschränkung einer guten Anamnese und des Wissens um die vielfältigen Ursachen. Man muss die Differenzialdiagnosen kennen, um sie auch erkennen zu können. Unser Fallbeispiel zeigt die Tücken einer vermeintlich leichten Diagnostik. Im vorliegenden Beitrag werden fast alle Proktitiden außer jener der chronisch-entzündlichen Darmerkrankungen beschrieben.

show abstract

Letter to the editor on: F. Campostrini et al. Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer

et al. 2020

View full text Add to dashboard Cite

Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer+

Cited by 8 publications

References 34 publications

A Ten-year-long Update on Radiation Proctitis Among Prostate Cancer Patients Treated With Curative External Beam Radiotherapy

A Ten-year-long Update on Radiation Proctitis Among Prostate Cancer Patients Treated With Curative External Beam Radiotherapy

Proktitis (ohne chronisch-entzündliche Darmerkrankung)

Letter to the editor on: F. Campostrini et al. Association between acute histopathological changes of rectal walls and late radiation proctitis following radiotherapy for prostate cancer

Contact Info

Product

Resources

About