Association analysis of the surfactant protein-C gene to childhood asthma

A systematic review of the role of surfactants in bronchial asthma: Implications for pathogenesis and treatment of the disease

“…The complexity of BA pathogenesis and the instability of response to treatment further emphasize the need for continued research to clarify the pathogenesis and search for new therapeutic targets in this disease. A promising direction in the study of BA pathogenesis is analyzing the role of surfactants, changes in the state of which are considered an aspect of the pathogenesis and diagnosis of the disease, as well as a potential therapeutic target (17)(18)(19). To date, the positive effect of surfactants has been established in several diseases and pathological conditions of the respiratory system, which is believed to be due to their protective properties (20,21).…”