Association Among Lower Urinary Tract Symptoms, Erectile Function, and Sexual Satisfaction: Results from the Brazil LUTS Study

Gomes, Cristiano Mendes; Averbeck, Márcio Augusto; Koyama, Mitti Ayako Hara; Soler, Roberto

doi:10.1016/j.esxm.2019.09.003

Cited by 10 publications

(4 citation statements)

References 40 publications

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“…In conclusion, urinary complications of DM have been associated with general discomfort and decreased quality of life, unfavourable psychological effects and possibly depression and psychiatric symptoms 157 . Recent findings have revealed that among men with DM, those with LUTS have a higher prevalence of ED than those without LUTS 158,159 …”

Section: The ‘Complicated Role’ Of Complications and Cofactors In The...mentioning

confidence: 99%

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Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Defeudis

Mazzilli

Tenuta

et al. 2021

Diabetes Metabolism Res

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Diabetes mellitus (DM), a chronic metabolic disease characterised by elevated levels of blood glucose, is among the most common chronic diseases. The incidence and prevalence of DM have been increasing over the years. The complications of DM represent a serious health problem. The long-term complications include macroangiopathy, microangiopathy and neuropathy as well as sexual dysfunction (SD) in both men and women. Erectile dysfunction (ED) has been considered the most important SD in men with DM. The prevalence of ED is approximately 3.5-fold higher in men with DM than in those without DM. Common risk factors for the development of DM and its complications include sedentary lifestyle, overweight/ obesity and increased caloric consumption. Although lifestyle changes may help improve sexual function, specific treatments are often needed. This study aims to review the definition and prevalence of ED in DM, the impact of DM complications and DM treatment on ED and, finally, the current and emerging therapies for ED in patients with DM.

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Section: The ‘Complicated Role’ Of Complications and Cofactors In The...mentioning

confidence: 99%

“… 157 Recent findings have revealed that among men with DM, those with LUTS have a higher prevalence of ED than those without LUTS. 158 , 159 …”

Section: The ‘Complicated Role’ Of Complications and Cofactors In The...mentioning

confidence: 99%

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Defeudis

Mazzilli

Tenuta

et al. 2021

Diabetes Metabolism Res

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“…Treatment of LUTS can also improve sexual function and alleviate associated mental health issues. Studies have reported that treatment of BPH-related LUTS can improve erectile function, libido, and overall sexual satisfaction (Gomes et al, 2020; Roehrborn et al, 2018). In addition, improvements in LUTS can lead to reduced anxiety, depression, and social isolation, leading to an overall improvement in mental health (Hughes et al, 2020) and a significant impact on the quality of life of older men, including sexual function and mental health.…”

Section: Discussionmentioning

confidence: 99%

Mitigating Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: Ameliorating Sexual Function and Psychological Well-Being in Older Men

Chan,

Estivalet

et al. 2023

Am J Mens Health

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This study aimed to investigate the prevalence of lower urinary tract symptoms (LUTS) in older men ( N= 3056) with benign prostatic hyperplasia (BPH) and its effects on their sexual function and mental health. Descriptive, correlation, and regression analyses were used to explore the relationships between prostate and lower urinary tract health and psychological well-being. Better prostate and lower urinary tract health positively affected psychological well-being, and sexual function also had a positive influence. LUTS have an adverse impact on sexual function and mental health. Early intervention is crucial for mitigating the negative impact of LUTS on the quality of life in older men. Addressing prostate and lower urinary tract health issues through appropriate interventions may improve psychological well-being. Health care professionals must consider the adverse effects of BPH and LUTS on sexual function and mental health, and implement interventions to enhance the overall quality of life in older men.

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“…1 By reducing prostate volume by approximately 20% from baseline, 5ARIs are effective for patients with urinary symptoms. 1 Although LUTS itself is an independent risk factor for erectile dysfunction (ED), [2][3][4] Evaluation of sexual function after dutasteride treatment in patients with once-negative prostate biopsy and benign prostate hyperplasia 5ARIs also exhibit erectile functional side effects. As reviewed by Traish et al, 5 several studies have demonstrated an effect of 5ARIs on diminished libido and erectile and ejaculatory function.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of sexual function after dutasteride treatment in patients with once-negative prostate biopsy and benign prostate hyperplasia

et al. 2023

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Introduction: Patients with benign prostatic hyperplasia are usually treated with 5α-reduced inhibitors (5ARIs) such as finasteride and dutasteride. However, studies on the influence of 5ARIs on sexual function have been controversial. In this study, we evaluated the impact of dutasteride treatment for erectile function in patients with once-negative prostate biopsy and benign prostate hyperplasia. Patients and methods: 81 patients with benign prostate hyperplasia were enrolled in a one-armed prospective study. They were administrated 0.5 mg/day of dutasteride for 12 months. Patient characteristics and changes of International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF)-15 scores at baseline and 12 months after dutasteride administration were examined. Results: The mean ± standard deviation (SD) age of the patients was 69.4 ± 4.9 years and the prostate volume was 56.6 ± 21.3 mL, respectively. The mean ± SD prostate volume and PSA levels were decreased 25.0 and 50.9%, respectively, after 12 months of dutasteride administration. IPSS total, voiding subscore, storage subscore, and quality of life score significantly improved after 12 months of dutasteride administration. No statistically significant change in IIEF-total score from 16.3 ± 13.5 to 18.8 ± 16.0 ( p = 0.14), IIEF-EF score from 5.1 ± 6.9 to 6.4 ± 8.3 ( p = 0.13) were observed. There was no decrease in erectile function severity. Conclusion: Twelve months administration of dutasteride for patients with BPH improved urinary function and did not increase the risk of sexual dysfunction.

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Association Among Lower Urinary Tract Symptoms, Erectile Function, and Sexual Satisfaction: Results from the Brazil LUTS Study

Cited by 10 publications

References 40 publications

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

Mitigating Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: Ameliorating Sexual Function and Psychological Well-Being in Older Men

Evaluation of sexual function after dutasteride treatment in patients with once-negative prostate biopsy and benign prostate hyperplasia

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