“…For the subset of patients who present with tumor and liver-related features amenable to surgery, hepatic resection—in addition to transplantation—offers the best chance at curative-intent therapy. Resection can be associated, however, with risk of complications and perioperative death especially among individuals with concomitant portal hypertension, liver fibrosis, cirrhosis, and portal vein thrombosis ( 1 - 3 ). Post-resection liver failure is also a major concern and can be a devasting complication following hepatic resection ( 4 , 5 ).…”